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기본 정보
- CAS
100488-87-7- 표준 SMILES
CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CC)C(C)=O)OC.[Cl-]- InChIKey
APUCCVGQZPNXIO-UHFFFAOYSA-N- 분자식
- C34H60ClN3O6
이름 및 식별자
- 우선 이름
- CV-6209
- 영어명
- CV-6209
- 분자식
- C34H60ClN3O6
- 분자량
- 0
이름 및 동의어
Cv 6209 chlorideCV-6209 (CV 62092-(N-Acetyl-N-(2-methoxy-3-octadecylcarbamoyloxypropoxycarbonyl)aminomethyl)-1-ethylpyridinium2-(2-Acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl- pyridinium ChloridePyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloridePyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride (1:1)
데이터베이스 식별자
- CAS
100488-87-7- PubChem CID
- 107756
- ChEMBL
CHEMBL274420
물성
물리화학적 성질
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 10 mg/ml · Water: 10 mg/ml
- 물리적 상태
- 결정성 고체
- 색상
- Off-white to light yellow
- 안정성
- -200 C에 · -200C에 보관하세요.
화학적 성질
Pale-Yelow Solid
화학 및 산업
응용 분야
개요CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid , histamine, bradykinin , or isoproterenol . CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.
용도Competitive PAF receptor antagonist. Inhibits PAF induced human platelet aggregation. Inhibits PAF induced hypotension and lethality.
공급사22 곳
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Aladdin Scientific[email protected]
湖北魏氏化学试剂股份有限公司027-59102966 18717199209 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
上海陶素生化科技有限公司021-33632979 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
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