기본 정보
- CAS
533-22-2- 표준 SMILES
N=C(N)c1ccc(C=Cc2ccc(C(=N)N)cc2O)cc1.O=S(=O)(O)CCO.O=S(=O)(O)CCO- InChIKey
XVTQTNAKZYLTNZ-UHFFFAOYSA-N- 분자식
- C20H28N4O9S2
- 평균 분자량
- 532.6 g/mol
- 단동위원소 질량
- 532.12977083
개요
Hydroxystilbamidine Isethionate is the isethionate salt form of hydroxystilbamidine, a cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating manner, and is a powerful inhibitor of ribonucleases, thereby impeding cellular processes in protozoa. This agent was also shown to bind to lysosomes and induced a large number of lysosome-like bodies and secretion granules in trypanosome.
이름 및 식별자
- 우선 이름
- Hydroxystilbamidine Isethionate
- IUPAC
- 4-[2-(4-carbamimidoylphenyl)ethenyl]-3-hydroxybenzenecarboximidamide;bis(2-hydroxyethanesulfonic acid)
- 영어명
- 2-hydroxyethanesulphonic acid, compound with 4-[2-(4-amidinophenyl)vinyl]-3-hydroxybenzenecarboxamidine (2:1)
- 분자식
- C18H22N4O5S
- 분자량
- 406.46
이름 및 동의어
533-22-20163PVD2QZ2-Hydroxy-4,4'-stilbenedicarboxamidine bis(2-hydroxyethanesulfonate) (salt)Benzenecarboximidamide, 4-(2-(4-(aminoiminomethyl)phenyl)ethenyl)-3-hydroxy-, bis(2-hydroxyethanesulfonate) (salt)2-hydroxy-4,4'-stilbenedicarboxamidine bis(2-hydroxyethanesulphonate) (salt)NSC-259242BENZENECARBOXIMIDAMIDE, 4-(2-(4-(AMINOIMINOMETHYL)PHENYL)ETHENYL)-3-HYDROXY-, BIS(2-HYDROXYETHANESULPHONATE) (SALT)HYDROXYSTILBAMIDINE ISETIONATE (MART.)HYDROXYSTILBAMIDINE ISETIONATE [MART.]RefChem:57469208-557-3Hydroxystilbamidine Isethionate
이름 더 보기
Einecs 208-557-3HYDROXYSTIBAMIDIENISETHIONATE2-Hydroxy-4,4'-stilbenedicarboxamidine diisethionate2-Hydroxy-4,4'-diamidinostilbene di(beta-hydroxyethanesulfonate)Ethanesulfonic acid, 2-hydroxy-, compd. with 2-hydroxy-4,4'-stilbenedicarboxamidine (2:1) (8ci)2-Hydroxyethanesulphonic acid, compound with 4-(2-(4-amidinophenyl)vinyl)-3-hydroxybenzenecarboxamidine (2:1)
물성
구조 계산 물성
- 극성 표면적
- 286 Ų
- 수소 결합 공여자 수
- 9
- 수소 결합 수용자 수
- 11
- 회전 가능 결합 수
- 8
- 무거운 원자 수
- 35
- 형식 전하
- 0
- 복잡도
- 530
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
물리화학적 성질
- 녹는점
- 286 ° · 286° (dec)
화학 및 산업
응용 분야
용도2-Hydroxystilbamidine Diisethionate is a transmembrane domain 5 self-association disruptor. 2-Hydroxystilbamidine Diisethionate inhibits full-length LMP-1 signaling in Epstein-Barr virus infected cells.
상·하류 제품 정보
상류 원료
공급사2 곳
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…