아시아티코사이드

Npc29838

HCID 108062

기본 정보

CAS
16830-15-2
표준 SMILES
CC1CCC2(C(=O)OC3OC(COC4OC(CO)C(OC5OC(C)C(O)C(O)C5O)C(O)C4O)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC43C)C2C1C
InChIKey
WYQVAPGDARQUBT-UHFFFAOYSA-N
분자식
C48H78O19
평균 분자량
959.1 g/mol
단동위원소 질량
958.51373025

개요

Asiaticoside has been reported in Centella erecta with data available.

이름 및 식별자

우선 이름
Npc29838
IUPAC
[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
현지명
아시아티코사이드
영어명
Asiaticoside
분자식
C48H78O19
분자량
959.12

이름 및 동의어

RefChem:1093047Npc29838DermatologicoBlastoestimulinaBa 2742Asiaticoside CRSMadecassol (TN)[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-tetrahydropyran-2-yl]oxymethyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl] 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylateBlastostimulinaMarticassolUrs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester, (2alpha,3beta,4alpha)-SCHEMBL664796
이름 더 보기
아시아티코사이드AsiaticosidesasiaticosidMADECASSOLBa-2742CENTELASEMADECASOLMeal snow
2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopyWYQVAPGDARQUBT-UHFFFAOYSA-NHMS5081H10NSC166062s3616AKOS015960549AC-6028FK 1080

데이터베이스 식별자

CAS
16830-15-2
PubChem CID
108062

물성

구조 계산 물성

XLogP
0.1
극성 표면적
315 Ų
수소 결합 공여자 수
12
수소 결합 수용자 수
19
회전 가능 결합 수
10
무거운 원자 수
67

실험 및 물리화학적 성질

Endocrine DisruptorsPotential endocrine disrupting compound
Melting Point235 - 238 °C
Physical DescriptionSolid

물리화학적 성질

녹는점
235 · 235-238°C
끓는 점
1017.5 · 1017.5±65.0 °C(Predicted)
밀도
1.44 · 1.44±0.1 g/cm3(Predicted)
증기압
0.001 Pa · 0.001Pa at 160℃
저장 조건
2 · under inert gas (nitrogen or Argon) at 2-8°C
용해도
DMSO(약간 용해됨), 에탄올(약간 용해됨, 가열, 초음파 처리), 메탄올(약간 용해됨)

화학적 성질

White powder

안전 및 규제

안전 데이터

wgk
3
rtecs
YU9625000
ridadr
UN 2811 6.1 / PGIII
HS 번호
29389090
safety_code
24/25
F 고인화성물질
1-10

화학 및 산업

약리 정보

Cellular LocationsCytoplasm
응용 분야 · 2건

개요Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.

용도Asiatic Acid is a terpenoid saponin component isolated from Centella asiatica with antioxidant and anti-inflammatory activities. Asiaticoside has been shown to possess strong wound-healing properties and reduces scar formation.

상·하류 제품 정보

상류 원료

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
成都普瑞法科技开发有限公司+86-028-82633397 18982077548 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
Shaanxi Huike Botanical Development Co., Ltd+86-29-62663046 · [email protected]

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