P-톨루이딘 수화염화물

Benzenamine, 4-methyl-, hydrochloride (1:1)

HCID 10891

기본 정보

CAS
540-23-8
표준 SMILES
Cc1ccc(N)cc1.Cl
InChIKey
JQKBUTDZZRGQDR-UHFFFAOYSA-N
분자식
C7H10ClN
평균 분자량
143.61 g/mol
단동위원소 질량
143.050177

이름 및 식별자

우선 이름
Benzenamine, 4-methyl-, hydrochloride (1:1)
IUPAC
4-methylaniline;hydrochloride
현지명
P-톨루이딘 수화염화물
영어명
4-Methylaniline hydrochloride
분자식
C7H10ClN
분자량
143.61

이름 및 동의어

p-Toluidine hydrochloride540-23-84-Aminotoluene hydrochloride4-Methylanilinium chloridep-Methylanilinium chloride4-Methylbenzenamine hydrochloridep-Toluidine, hydrochloridePT5II901IFBenzenamine, 4-methyl-, hydrochloride (1:1)P-METHYLANILINE HYDROCHLORIDE4-METHYLPHENYLAMMONIUM CHLORIDE4-toluidine hydrochloride
이름 더 보기
P-톨루이딘수화염화물P-톨루이딘수화염화물(P-TOLUIDINEHYDROCHLORIDE)톨루이디늄클로라이드4-methylaniline HCLToluidinium chloridep-Toluidine hydrochloriρ-Toluidine hydrochliride4-methylaniliniumchloridep-methylaniliniumchloride
RefChem:169393208-740-84-Methylaniline hydrochloridep-Toluidine.HClBenzenamine, 4-methyl-, hydrochloridep-TOLUIDINE HClP-TOLUIDINIUM CHLORIDEDTXSID2021365

데이터베이스 식별자

CAS
540-23-8
PubChem CID
10891
DTXSID
DTXSID2021365
ChEMBL
CHEMBL3183830
UNII
PT5II901IF
EC Number
208-740-8

물성

구조 계산 물성

극성 표면적
26 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
1
회전 가능 결합 수
0
무거운 원자 수
9

실험 및 물리화학적 성질

Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Boiling Point495.5 °F at 760 mmHg (NTP, 1992)
Melting Point469 °F (NTP, 1992)
Physical Description · 2건

P-toluidine hydrochloride appears as off-white to grayish-white crystals. (NTP, 1992)

Off-white to grayish-white solid; [CAMEO] Off-white powder; [Anachemia MSDS]

물리화학적 성질

녹는점
243 · 243-245 °C(lit.)
밀도
1.193 g/cm3 · 1.193 g/cm3
저장 조건
30 °C · Store below +30°C.
수용성
물에 용해됨
용해도
DMSO(적게), 메탄올(약간)에 용해됨
물리적 상태
powder to crystal

화학적 성질

white to light beige crystalline powder, crystals

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral];H311: Toxic in contact with skin [Danger Acute toxicity, dermal];H317: May cause an allergic skin reaction [Warning Sensitization, Skin];H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation];H331: Toxic if inhaled [Danger Acute toxicity, inhalation];H351: Suspected of causing cancer [Warning Carcinogenicity];H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P203, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P321, P330, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Danger

유해성 정보

Regulatory Information · 2건

Chemical: Benzenamine, 4-methyl-, hydrochloride

4-Toluidine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - p-Toluidine and its salts: Human health tier II assessment
Fire HazardsFlash point data for this chemical are not available, but it is probably combustible. (NTP, 1992)
Health Hazards · 1건

SYMPTOMS: Symptoms of exposure to this compound are cyanosis, air hunger, nausea, vomiting, low blood pressure and convulsions. Chronic exposure results in weight loss, weakness and anemia.;ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits very toxic fumes. (NTP, 1992)

Hazards Summary · 1건

A skin and severe eye irritant; May cause skin sensitization; May induce methemoglobinemia; Highly toxic by ingestion, inhalation, and skin absorption; Targets the blood, liver, kidney, and lung; Possible mutagen and carcinogen; [Anachemia MSDS] See p-Toluidine.

Reactive GroupSalts, Acidic

안전 및 보호

Fire FightingFires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.;SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.;INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.;INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.;STORAGE PRECAUTIONS: You should store this chemical under refrigerated temperatures, protect from moisture and keep it away from oxidizing materials. (NTP, 1992)

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

독성 정보

Adverse EffectsMethemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect;Skin Sensitizer - An agent that can induce an allergic reaction in the skin.

규제 정보

Regulatory Information · 2건

Chemical: Benzenamine, 4-methyl-, hydrochloride

4-Toluidine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
XU7525000
ridadr
UN 2811 6.1/PG 1
HS 번호
29214300
risk_code
23/24/25-36-40-43-50

화학 및 산업

용도 및 제조

UsesUsed as an intermediate for dyes and for glucose detection in blood; [NTP]
General Manufacturing InformationBenzenamine, 4-methyl-, hydrochloride (1:1): INACTIVE

응용 분야

일반 설명Off-white to grayish-white crystals.

공급사54 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
阿诺西(上海)生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]

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