Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-나이트로-o-톨루이딘
6-나이트로-o-톨루이딘 · 2-AMINO-3-NITROTOLUENE · 6-NITRO-O-TOLUIDINE · 3-NITRO-2-AMINOTOLUENE · 2-Amino-3-nitro toulene · NSC 286 · NSC 52218 · -6-nitroaniL
식별자 및 물리적 특성
| CAS No. | 570-24-1 |
|---|---|
| 분자식 | C7H8N2O2 |
| 평균 분자량 | 152.15 g/mol |
| 단동위원소 질량 | 152.0585775 g/mol |
| SMILES | Cc1cccc([N+](=O)[O-])c1N |
| InChIKey | FCMRHMPITHLLLA-UHFFFAOYSA-N |
| PubChem CID | 11298 |
| EC No. | 209-329-6 |
| DTXSID | DTXSID7025631 |
| 현지명 | 6-나이트로-o-톨루이딘 |
화학 및 물리적 성질
| XLogP | 2 |
|---|---|
| 극성 표면적 | 71.8 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 3 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 11 |
| 형식 전하 | 0 |
| 복잡도 | 155 |
| 물질 분류 | Nitrogen Compounds -> Nitroanilines |
| 화장품 | Hair dyeing |
| SpringerMaterials Properties | Surface tension |
| 밀도 | 1.19 at 212 °F (NTP, 1992) - Denser than waterwill sink1.19 g/cm3 |
| 용해도 | less than 1 mg/mL at 73 °F (NTP, 1992)<1mg/L |
| 녹는점 | 199 to 205 °F (NTP, 1992)93-96 °C (lit.) |
| Physical Description | 2-methyl-6-nitroaniline appears as orange-yellow prisms or brown granular powder. (NTP, 1992)Orange-yellow or brown solid[CAMEO] Dark red solid[EC: SCCNFP] Dark red crystalline solid[Sigma-Aldrich MSDS] |
| 끓는 점 | 124 °C / 1mmHg |
| 굴절률 | 1.6276 (estimate) |
| 인화점 | 110 °C |
| 저장 조건 | Keep in dark place,Inert atmosphere,Room temperature |
| pKa(산도 계수) | -0.44±0.25(Predicted) |
| 물리적 상태 | 결정성 분말 |
| 색상 | 갈색을 띠는 |
| 용해도 | 23&C에서 <0.1g/100mL |
| BRN | 1868029 |
| 헨리 상수 | 4.6×101 mol/(m3Pa) at 25℃, Abraham and Jr. (2019) |
| 화장품 원료 기능 | 머리 염색 |
| InChI | 1S/C7H8N2O2/c1-5-3-2-4-6(7(5)8)9(10)11/h2-4H,8H2,1H3 |
| InChIKey | FCMRHMPITHLLLA-UHFFFAOYSA-N |
| SMILES | Cc1cccc(c1N)[N+]([O-])=O |
| NIST | 2-Methyl-6-nitroaniline(570-24-1) |
| EPA | 2-Methyl-6-nitroaniline (570-24-1) |
화학적 성질
Redish-Brown Solid
안전 및 규제
| GHS 분류 | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P260, P261, P262, P264, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P316, P319, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H311: Toxic in contact with skin [Danger Acute toxicity, dermal] |
|---|---|
| 규제 정보 | Chemical: Benzenamine, 2-methyl-6-nitro-Status: No longer Valid Update: 25-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/245956-Nitro-o-toluidine: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Benzenamine, 2-methyl-6-nitro-: Human health tier II assessment |
| 운송 라벨(DOT) | Poison |
| 화재 위험 | Flash point data for this compound are not available, but it is probably combustible. (NTP, 1992) |
| 건강 유해성 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| 유해성 요약 | A mild skin and eye irritant in rabbits at 3% concentration in 1,2-propanediolNo evidence of skin sensitization in guinea pigsHepatotoxicity observed in 28-day oral studies of ratsNo evidence of embryotoxicity or teratogenicity in rats[EC: SCCNFP] May cause irritationMay induce methemoglobinemiaToxic by ingestion, inhalation, and skin absorptionTargets the blood[Sigma-Aldrich MSDS] See 2-Nitroaniline. |
| 반응성 그룹 | Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic |
| Reactivity Profile | 2-METHYL-6-NITROANILINE is incompatible with acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizers. (NTP, 1992) |
| Air and Water Reactions | This chemical is sensitive to prolonged exposure to air. Insoluble in water. |
| Hazard Classes and Categories | Acute Tox. 3 (100%)Acute toxicity - category 3 |
| 소화 | Fires involving this material can be controlled using a carbon dioxide, dry chemical or Halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 비화재 누출 대응 | SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Isolation and Evacuation | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| 유해 작용 | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
| 수질 위해 등급(WGK) | 3 |
| 운송 번호(UN) | UN 2660 6.1/PG 3 |
| 관세 코드 | 29214300 |
| 위험 문구(R) | 23/24/25-33-51/53 |
| 위험 표시 | T,N,Xi |
| 안전 문구(S) | 28-36/37-45-61-28A |
| 포장분류 | Ⅲ |
| 위험 등급 | IRRITANTAcute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 2STOT RE 2 |
| F 고인화성물질 | 10 |
| 위험 참고 사항 | Toxic |
| 저장 분류 | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
용도
일반 설명
Orange-yellow prisms or brown granular powder.