Galanthamine N-Oxide

HCID 11748698

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 199014-26-1
표준 SMILES: COc1ccc2c3c1O[C@H]1C[C@@H](O)C=C[C@@]31CC[N+](C)([O-])C2
InChIKey: LROQBKNDGTWXET-FVWDGWMTSA-N
분자식: C17H21NO4
평균 분자량: 303.35 g/mol
단동위원소 질량: 303.14705815

이름 및 식별자

우선 이름: Galanthamine N-Oxide
IUPAC: (1S,12S,14R)-9-methoxy-4-methyl-4-oxido-11-oxa-4-azoniatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
영어명: LROQBKNDGTWXET-FVWDGWMTSA-N
분자식: C17H21NO4
분자량: 303.35

이름 및 동의어

Galanthamine N-OxideGalantamine N-OxideUNII-S6AF61T5WOS6AF61T5WO(1S,12S,14R)-9-methoxy-4-methyl-4-oxido-11-oxa-4-azoniatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-olDTXSID40173681GALANTAMINE METABOLITE M10GALANTHAMINE (RS)-N-OXIDE(4AS-(4A.ALPHA.,6.BETA.,8AR*))-4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, N-OXIDE6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-, 11-OXIDE, (4AS,6R,8AS)-6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-, 11-OXIDE, (4AS-(4A.ALPHA.,6.BETA.,8AR*))-(1S,12S,14R)-9-methoxy-4-methyl-4-oxido-11-oxa-4-azoniatetracyclo(8.6.1.01,12.06,17)heptadeca-6(17),7,9,15-tetraen-14-ol

이름 더 보기

Galantamine Impurity 2Galantamine Impurity 5Galantamine EP impurityLROQBKNDGTWXET-FVWDGWMTSA-NPhenylgalantamine impurity 31Impurity H of galanthamine hydrobromide(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-oxide6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 11-oxide, (4aS,6R,8aS)-(4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepine 11-oxide

RefChem:142153DTXCID2096172GALANTAMINE HYDROBROMIDE IMPURITY, 6.BETA.-HEXAHYDROGALANTAMINE-[USP IMPURITY]GALANTAMINE HYDROBROMIDE IMPURITY, 6BETA-HEXAHYDROGALANTAMINE-(USP IMPURITY)(4AS-(4AALPHA,6BETA,8AR*))-4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, N-OXIDE6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-, 11-OXIDE, (4AS-(4AALPHA,6BETA,8AR*))-199014-26-1Nivalin-oxide

데이터베이스 식별자

CAS: 199014-26-1
PubChem CID: 11748698
DTXSID: DTXSID40173681
UNII: S6AF61T5WO
Nikkaji: J391.066K

물성

구조 계산 물성

XLogP: 1.3
극성 표면적: 56.8 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 4
회전 가능 결합 수: 1
무거운 원자 수: 22
형식 전하: 0
복잡도: 483

물리화학적 성질

산도 계수 (pKa): 13.84 · 13.84±0.20(Predicted)
주요 응용: 소분자 약용

화학 및 산업

약리 정보

Metabolism/MetabolitesGalantamine N-oxide is a known human metabolite of galantamine.

응용 분야

용도(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-oxide is studied for its potential use as neuroprotective compounds from the bulbs of Lycoris radiata.

공급사31 곳

广州佳途科技股份有限公司81960175 18933936954 · [email protected]

湖北瑞玛标物科技有限公司15787879035 15787875101 · [email protected]

深圳鼎邦化学品有限公司15616500668 · [email protected]

仙桃市丽昭医药科技有限公司18571672902 · [email protected]

南京望知星医药科技有限公司18569809817 · [email protected]

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