홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /화합물

트리페닐라르신

Triphenylarsine

HCID 11773
새 노트새 반응견적 요청하기
인쇄 미리보기
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
603-32-7
표준 SMILES
c1ccc([As](c2ccccc2)c2ccccc2)cc1
InChIKey
BPLUKJNHPBNVQL-UHFFFAOYSA-N
분자식
C18H15As
평균 분자량
306.2 g/mol
단동위원소 질량
306.03897

개요

Triphenylarsine is an organoarsenic compound. It is used as a ligand and a reagent in coordination chemistry and organic synthesis. Arsenic is a chemical element that has the symbol As and atomic number 33. It is a poisonous metalloid that has many allotropic forms: yellow (molecular non-metallic) and several black and grey forms (metalloids) are a few that are seen. Three metalloidal forms of arsenic with different crystal structures are found free in nature (the minerals arsenopyrite and the much rarer arsenolamprite and pararsenolamprite), but it is more commonly found as a compound with other elements. (T3, L398)

이름 및 식별자

우선 이름
Triphenylarsine
IUPAC
triphenylarsane
현지명
트리페닐라르신
영어명
Triphenylarsine
분자식
C18H15As
분자량
306.23

이름 및 동의어

TRIPHENYLARSINE603-32-7TriphenylarsaneArsine, triphenyl-TriphenylarseneTriphenyl arsenicMN8EZ3FL74NSC-478DTXSID4060529RefChem:191898DTXCID6042787210-032-9
이름 더 보기
트리페닐라르신Triphenyl-arsaneNSC 478triphenyl-arsinTriphenylarsine,97%Triphenylarsine,98%
ArsinetriphenylMFCD00002994TriphenylarsenicArsenic triphenylC18H15Astriphenyl arsinetriphenyl-arsineNSC478

데이터베이스 식별자

CAS
603-32-7
PubChem CID
11773
DTXSID
DTXSID4060529
UNII
MN8EZ3FL74
EC Number
210-032-9
Nikkaji
J44.111B

물성

구조 계산 물성

극성 표면적
0 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
0
회전 가능 결합 수
3
무거운 원자 수
19
형식 전하
0
복잡도
202

실험 및 물리화학적 성질

Chemical ClassesMetals -> Arsenic Compounds, Organic
Vapor Pressure0.0000496 [mmHg]
Physical DescriptionWhite powder; [Alfa Aesar MSDS] Fine colorless crystals; [Aldrich MSDS]

물리화학적 성질

녹는점
58 · 58-61 °C (lit.)
끓는 점
360 °C · 360 °C
밀도
1 · 1,225 g/cm3
굴절률
1.6888 · 1.6888
인화점
265 °C · 265 °C
저장 조건
30 °C · Store below +30°C.
물리적 상태
가루
Specific Gravity
1.2225 · 1.2225
색상
하얀색
수용성
메탄올에 용해됩니다. 물에 불용성.
BRN
1842037 · 1842037
InChI
1S/C18H15As/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChIKey
BPLUKJNHPBNVQL-UHFFFAOYSA-N
SMILES
c1ccc(cc1)[As](c2ccccc2)c3ccccc3

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 4건

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P264, P270, P271, P273, P301+P316, P304+P340, P316, P321, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Restricted substance: Triphenylarsine

Triphenylarsine: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

An irritant; Toxic by ingestion and inhalation; [Alfa Aesar MSDS] Almost nothing is known regarding health effects of organic arsenic compounds in humans. Studies in animals show that some simple organic arsenic compounds are less toxic than inorganic forms. Ingestion of methyl and dimethyl compounds can cause diarrhea and damage to the kidneys. [ATSDR ToxProfiles] See Dimethylarsenic acid.

Hazard Classes and CategoriesAcute Tox. 3 (100%)

안전 및 보호

Minimum Risk LevelAcute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)
Permissible Exposure Limit (PEL)0.5 [mg/m3], as As

독성 정보

Treatment

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)

용도 및 제조

UsesTriphenylarsine is used as a ligand and a reagent in coordination chemistry and organic synthesis. (L398)
General Manufacturing InformationArsine, triphenyl-: ACTIVE

응용 분야

용도Triphenylarsine is used in certain metal-catalyzed coupling reactions. It is a precursor to tetraphenylarsonium chloride a popular precipitating agent.

상·하류 제품 정보

하류 제품

텅스텐,펜타카르보닐(트리페닐아르신)-(OC-6-22)-

관련 반응

190건
반응 기록 만들기
HRID 14608 반응식
HRID 14608반응물로uspto-grants-2010_06
HRID 33001 반응식
HRID 33001반응물로uspto-grants-2008_09
HRID 33662 반응식
HRID 33662반응물로uspto-grants-2008_09
HRID 53280 반응식
HRID 53280촉매로uspto-grants-1997_04
HRID 70769 반응식
HRID 70769반응물로uspto-grants-2014_09
HRID 72786 반응식
HRID 72786반응물로uspto-grants-2014_09
HRID 86008 반응식
HRID 86008반응물로Training data from https://doi.org/10.1039/C8SC04228D (2/10)
HRID 91724 반응식
HRID 91724반응물로Training data from https://doi.org/10.1039/C8SC04228D (2/10)
1 / 24 페이지

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
더보기
새 노트새 반응견적 요청하기
EPA
Arsine, triphenyl- (603-32-7)

화학적 성질

COLOURLESS TO SLIGHTLY YELLOW CRYSTALLINE SOLID

· 1건

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Exposure RoutesOral (L2) ; inhalation (L2) ; dermal (L2)
Toxicity Summary · 1건

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and SymptomsExposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of
Carcinogen Classification3, not classifiable as to its carcinogenicity to humans. (L135)

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
CH8942500
ridadr
UN 3465 6.1/PG 2
HS 번호
2931 90 00
risk_code
23/25-50/53
hazard_code
T,N
safety_code
20/21-28-45-60-61
포장분류
II
위험 등급
6.1
Hazard Classifications
Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1
스토리지 클래스
6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials