7-Methylquinoline

HCID 11927CAS 612-60-2

기본 정보

표준 SMILES
Cc1ccc2cccnc2c1
InChIKey
KDYVCOSVYOSHOL-UHFFFAOYSA-N
분자식
C10H9N
평균 분자량
143.18 g/mol
단동위원소 질량
143.07349929

개요

7-methylquinoline appears as clear yellow liquid or oil. (NTP, 1992)

이름 및 식별자

우선 이름
7-Methylquinoline
IUPAC
7-methylquinoline
영어명
7-Methylquinoline
분자식
C10H9N
분자량
143.19

이름 및 동의어

7-METHYLQUINOLINE612-60-2m-ToluquinolineQuinoline, 7-methyl-CCRIS 2895DTXSID5025657EINECS 210-316-2UNII-EOW995K43CNSC 65665BRN 0110317EOW995K43CAI3-00850
이름 더 보기
7-methyquinoline7-Methylchinolin7-methyl-quinolin7-Methylquinolinol7-MethylquiuolineQuinolinol,7-methyl-7-Methylquinoline>
NSC-65665METHYLQUINOLINE, 7-DTXCID0056575-20-07-00402 (Beilstein Handbook Reference)mToluquinolineQuinoline, 7methylRefChem:106391210-316-2

데이터베이스 식별자

CAS
612-60-2
PubChem CID
11927
DTXSID
DTXSID5025657
ChEMBL
CHEMBL1322524
UNII
EOW995K43C
EC Number
210-316-2
Nikkaji
J842G

물성

구조 계산 물성

XLogP
2.5
극성 표면적
12.9 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
1
회전 가능 결합 수
0
무거운 원자 수
11

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Quinolines
SpringerMaterials PropertiesBoiling point
LogP2.47
Density1.0609 at 68 °F (NTP, 1992) - Denser than water; will sink
Solubilityless than 1 mg/mL at 68 °F (NTP, 1992)
Flash Point230 °F (NTP, 1992)

물리화학적 성질

녹는점
35 · 35-37 °C(lit.)
끓는 점
258 °C · 258 °C(lit.)
밀도
1.061 · 1.061
굴절률
1.607 to · 1.6070 to 1.6210
인화점
230 °F · >230 °F
저장 조건
Room Temperature

화학적 성질

white to light yellow crystal powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

DOT LabelCorrosive
Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsSYMPTOMS: This compound may be absorbed through the skin and it causes skin irritation. The vapor or mist is irritating to the eyes, mucous membranes and upper respiratory tract.
Hazards SummaryA skin irritant; Vapor or mist causes eye, mucous membranes, and upper respiratory tract irritation; May be absorbed through skin; [NTP] An irritant; Risk of irreversible adverse health effects; [Alfa Aesar MSDS] See Quinoline.
Reactive GroupAmides and Imides
Reactivity Profile · 1건

7-METHYLQUINOLINE may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
VC0560000
HS 번호
29334900
risk_code
37/38-41
hazard_code
Xi

화학 및 산업

용도 및 제조

General Manufacturing InformationQuinoline, 7-methyl-: ACTIVE
응용 분야 · 2건

용도7-methylquinoline has been bioassayed as tumor initiator on the skin of Sencar mice.

일반 설명7-Methylquinoline is a reagent used in the preparation of diarylmethylpiperazines as potent opioid receptor agonists with improved side effects. Also used in the preparation of novel pyrazine compounds derived from 2-phenylquinolin-7-yl which act as potent insulin-like growth factor-I receptor inhibitors.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
阿诺西(上海)生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海策嵘生物科技有限公司[email protected]

관련 반응

23건

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