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디브롬프로파미딘

Dibrompropamidine

HCID 11974
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
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기본 정보

CAS
496-00-4
표준 SMILES
N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2Br)c(Br)c1
InChIKey
GMJFVGRUYJHMCO-UHFFFAOYSA-N
분자식
C17H18Br2N4O2
평균 분자량
470.2 g/mol
단동위원소 질량
467.97965

개요

Dibrompropamidine is an aromatic ether.

이름 및 식별자

우선 이름
Dibrompropamidine
IUPAC
3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
현지명
디브롬프로파미딘
영어명
Dibrompropamidine
분자식
C17H18Br2N4O2
분자량
470.16

이름 및 동의어

DibrompropamidineDibromopropamidine496-00-4DibromopropamidinaDibrompropamidinumdibrompropamidina269M3QL74SDTXSID901979184,4'-(Trimethylenedioxy)bis(3-bromobenzamidine)3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzene-1-carboximidamide3-bromo-4-(3-(2-bromo-4-carbamimidoylphenoxy)propoxy)benzene-1-carboximidamideRefChem:132915
이름 더 보기
디브롬프로파미딘4,4'-(Trimethylenebisoxy)bis(3-bromobenzamidine)4,4'-[1,3-Propanediylbisoxy]bis(3-bromobenzamidine)4,4'-[1,3-Propanediylbis(oxy)]bis(3-bromobenzamidine)Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis[3-bromo-
D08AC01DTXCID50120409S01AX14Dibrompropamidine [INN]3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzenecarboximidamideCHEMBL30044Dibrompropamidine (INN)NCGC00189076-01

데이터베이스 식별자

CAS

물성

구조 계산 물성

XLogP
3.2
극성 표면적
118 Ų
수소 결합 공여자 수
4
수소 결합 수용자 수
4
회전 가능 결합 수
8
무거운 원자 수
25
형식 전하
0
복잡도
426

실험 및 물리화학적 성질

Chemical ClassesOther Uses -> Biocides/Disinfectants

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

독성 정보

Treatment · 1건

EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.

Health Effects · 1건

Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627)

Exposure RoutesOral (L626) ; inhalation (L626) ; dermal (L626)
Toxicity Summary · 1건

Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543)

Signs and Symptoms · 1건

Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways, coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. This is called bromism. (L626, L627)

화학 및 산업

약리 정보

ATC Code · 4건

S - Sensory organs

D - Dermatologicals

QD - Dermatologicals

QS - Sensory organs

Metabolism/Metabolites · 1건

Bromine is mainly absorbed via inhalation, but may also enter the body through dermal contact. Bromine salts can be ingested. Due to its reactivity, bromine quickly forms bromide and may be deposited in the tissues, displacing other halogens. (L626)

MeSH Pharmacological ClassificationSubstances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.

용도 및 제조

Uses · 3건

Dibromopropamidine isethionate is used as an antiseptic, antiamebic, and cosmetic preservative; [Merck Index]

Using Disinfectants or Biocides [Category: Clean]

As dibrompropamidine isethionate, it is also used in eyedrops and ointment for the treatment of infections. Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock.

상·하류 제품 정보

상류 원료

암모니아(가스)염산

공급사2 곳

杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
湖北清北云研医药科技有限责任公司18162595016; 18162595016 · [email protected]

관련 반응

2건
반응 기록 만들기
HRID 551575 반응식
HRID 551575반응물로uspto-grants-2011_05
HRID 1671367 반응식
HRID 1671367반응물로uspto-grants-2011_08

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
496-00-4
PubChem CID
11974
DTXSID
DTXSID90197918
ChEMBL
CHEMBL30044
ChEBI
CHEBI:135760
UNII
269M3QL74S
Nikkaji
J238.537F
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).