2-Ethyl butylamine

HCID 12049CAS 617-79-8

기본 정보

표준 SMILES
CCC(CC)CN
InChIKey
MGWAGIQQTULHGU-UHFFFAOYSA-N
분자식
C6H15N
평균 분자량
101.19 g/mol
단동위원소 질량
101.12044948

이름 및 식별자

우선 이름
2-Ethyl butylamine
IUPAC
2-ethylbutan-1-amine
영어명
2-Ethylbutylamine
분자식
C6H15N
분자량
101.19

이름 및 동의어

2-Ethylbutylamine617-79-81-Butanamine, 2-ethyl-Butylamine, 2-ethyl-1-Amino-2-ethylbutane2-ETHYL BUTYLAMINEHSDB 2749EINECS 210-530-64MFV23BJBABRN 17312962-Ethyl-1-butanamineDTXSID00210703
이름 더 보기
2-ethyl-butylamin2-ethyl-1-butanamin2-ETHYL-N-BUTYLAMINE2-Ethylbutylamine,97%3-(aMinoMethyl)pentane2-Ethyl-N-butylamine ,98%2-Ethyl-1-butylamine, 97%
3-04-00-00366 (Beilstein Handbook Reference)(2-ETHYL-N-BUTYL)AMINE2-ETHYL BUTYLAMINE [HSDB]2ethylbutylamine1Amino2ethylbutaneButylamine, 2ethyl1Butanamine, 2ethylRefChem:471697

데이터베이스 식별자

CAS
617-79-8
PubChem CID
12049
DTXSID
DTXSID00210703
UNII
4MFV23BJBA
EC Number
210-530-6
Nikkaji
J35.116D

물성

구조 계산 물성

XLogP
1.3
극성 표면적
26 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
1
회전 가능 결합 수
3
무거운 원자 수
7

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
OdorAmine odor
Density0.776 @ 20 °C/20 °C
Color/FormWater-white liquid
SolubilitySoluble in methyl and ethyl alcohols, ethyl ether, ethyl acetate, acetone, aromatic and aliphatic hydrocarbons, fixed oils, mineral oil, oleic and stearic acids.
Boiling Point125 °C

물리화학적 성질

녹는점
20 °C · 20°C
끓는 점
125 · 125
밀도
0.776 · 0.776
굴절률
1.41 · 1.4100
인화점
14 °C · 14 °C
저장 조건
Flammables area

화학적 성질

clear colorless to light yellow liquid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H225 (66.7%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P321, P330, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Fire PotentialA very dangerous fire hazard when exposed to heat or flame ...
Hazards Summary · 1건

Flammable liquid; [Hawley] A skin and severe eye irritant; [SAX] External application to rabbit eyes scored 9 on a scale of 1-10 (10 being most severe) for degree of injury after 24 hours; Emergency treatment: Irritants; [HSDB] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; May be absorbed through skin; Inhalation may result in chemical pneumonitis; [MSDSonline]

Hazard Classes and CategoriesAcute Tox. 4 (100%)
Skin, Eye, and Respiratory IrritationsA skin and severe eye irritant.
Hazardous Reactivities and Incompatibilities... Can react with oxidizing materials.

안전 및 보호

Fire Fighting ProceduresTo fight fire, use dry chemical, carbon dioxide, foam.
Disposal Methods · 1건

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Preventive Measures · 2건

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Keep away from heat and open flame.

독성 정보

Adverse EffectsDermatotoxin - Skin burns.
Non-Human Toxicity Excerpts · 3건

2-ETHYLBUTYLAMINE RATED 9 ON RABBIT EYES /ON SCALE OF 1-10 WITH ATTENTION TO DEGREE OF CORNEAL INJURY 24 HR AFTER EXTERNAL APPLICATION./

INHALATION TOXICITY: RATS EXPOSED TO 2200 PPM FOR 4 HR RESULTED IN MORTALITY RATE OF 0/6. /FROM TABLE/

SKIN IRRITATION TO RABBITS GRADED 6. 6= MORE NECROSIS FROM UNDILUTED, LESS THAN EDEMA FROM 10%. /FROM TABLE/

Antidote and Emergency Treatment · 2건

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush the eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Organic Bases/Amines and Related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV of D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Monitor for signs of hypoglycemia (decreased LOC, tachycardia, pallor, dilated pupils, diaphoresis, and/or dextrose stick or glucometer readings below 50 mg/dL) and administer 50% dextrose if necessary. Draw blood sample before administration ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic Bases/Amines and Related compounds/

Toxicity DataLC50 (rat) = 500 ppm/4h
Non-Human Toxicity Values · 5건

LD50 Rat oral 310 mg/kg

LC50 Rat ihl 500 ppm/ 4 hr

LD50 Rabbit skin 2000 mg/kg

LD50 Rat oral 0.39 g/kg

LD50 Rabbit skin 2.00 ml/kg

안전 데이터

wgk
WGK 3
ridadr
2733
HS 번호
2921199990
risk_code
34-20/21/22-11-36-22
hazard_code
C-F,F,C,Xn
safety_code
45-36/37/39-26-16

화학 및 산업

용도 및 제조

UsesUsed as an intermediate; [Hawley]

응용 분야

용도2-Ethylbutylamine is used in preparation of Amide-substituted Heterocyclic compounds for the treatment of conditions related to the modulation of IL-12, IL-23 and/or IFN-alpha.

공급사43 곳

苏州道澜生物医药科技有限公司15952404857 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
西安华瑞致远生物科技有限公司18014474522 · [email protected]
Aladdin Scientific[email protected]
石家庄衍晟生物科技有限公司18332018567; 18332018567 · [email protected]

관련 반응

35건

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