(+-)-탐수로신

5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

HCID 121829
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기본 정보

CAS
94666-07-6
표준 SMILES
CCOc1ccccc1OCCNC(C)Cc1ccc(OC)c(S(N)(=O)=O)c1
InChIKey
DRHKJLXJIQTDTD-UHFFFAOYSA-N
분자식
C20H28N2O5S
평균 분자량
408.5 g/mol
단동위원소 질량
408.17189317

이름 및 식별자

우선 이름
5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
IUPAC
5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
현지명
(+-)-탐수로신
영어명
(+-)-Tamsulosin
분자식
C20H28N2O5S
분자량
408.51

이름 및 동의어

94666-07-6CHEBI:1425465-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamideRefChem:529183926-076-3Racemic Tamsulosin(+-)-TamsulosinBenzenesulfonamide, 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-Amsulosin5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
이름 더 보기
(+-)-탐수로신Zavegepant Impurity 11Tamsulosin Impurity 12 Monomer(Tamsulosin Monomer Racemate)Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-5-[2-[2-(2-ethoxyphenoxy)-ethylamino]-2-methylethyl]-2-methoxybenzenesulfonamideBenzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy- (9CI)
YM 12617YM-12617Harnal-D5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]]-2-methoxybenzenesulfonamidebenzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, hydrochlorideTamsolusinSpectrum4_000788SCHEMBL53998

데이터베이스 식별자

CAS
94666-07-6
PubChem CID
121829
ChEBI
CHEBI:142546
EC Number
926-076-3
Nikkaji
J330.327F

물성

구조 계산 물성

XLogP
2.7
극성 표면적
108 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
7
회전 가능 결합 수
11
무거운 원자 수
28

물리화학적 성질

끓는 점
595.5 · 595.5±60.0 °C(Predicted)
밀도
1.191 · 1.191±0.06 g/cm3(Predicted)
산도 계수 (pKa)
10.08 · 10.08±0.60(Predicted)

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory InformationStatus: Active Update: 30-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/26184
Hazard Classes and CategoriesAcute Tox. 4 (100%)

규제 정보

Regulatory InformationStatus: Active Update: 30-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/26184

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.

Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS.

공급사3 곳

TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
湖北扬信医药科技有限公司15374522761 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]

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