Ethyl Thioglycolate (HCID 12185)

개요

Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.

이름 및 식별자

우선 이름: Ethyl Thioglycolate
IUPAC: ethyl 2-sulfanylacetate
현지명: 에틸티오글라이콜레이트
영어명: Ethyl Thioglycolate
분자식: C4H8O2S
분자량: 120.17

이름 및 동의어

Ethyl thioglycolate623-51-8Ethyl 2-mercaptoacetateEthyl mercaptoacetateUSAF EK-2070Thioglykolsaeure-aethylesterNSC 8834Ethyl .alpha.-mercaptoacetateAcetic acid, 2-mercapto-, ethyl ester2-mercaptoacetic acid ethyl esterUNII-Z5SD8DD6CPZ5SD8DD6CP

이름 더 보기

에틸티오글라이콜레이트THIOGLYCOLIC ACID ETHYL ESTERusafek-2070EthylthioglykolatEthyl thioglycolatEthylsulfanylacetatThioglycolate ethyl

EINECS 210-800-3Thioglykolsaeure-aethylester [German]BRN 0605581AI3-23030NSC-8834Ethyl alpha-mercaptoacetateETHOXYCARBONYLMETHANETHIOL4-03-00-00616 (Beilstein Handbook Reference)

데이터베이스 식별자

CAS: 623-51-8
PubChem CID: 12185
DTXSID: DTXSID8049337
ChEMBL: CHEMBL3181965
UNII: Z5SD8DD6CP
EC Number: 210-800-3
Nikkaji: J49.275B

물성

구조 계산 물성

XLogP: 0.8
극성 표면적: 27.3 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 3
무거운 원자 수: 7
형식 전하: 0
복잡도: 62.7

실험 및 물리화학적 성질

Chemical ClassesOther Classes -> Esters, Other

Cosmetics · 2건

Cosmetic ingredients (Ethyl Thioglycolate) -> CIR (Cosmetic Ingredient Review)

Hair waving or straightening; Reducing; Depilatory

SpringerMaterials PropertiesOptical coefficient

Physical DescriptionColorless liquid with a stench; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: -80 °C · -80 °C
끓는 점: 54 °C/12 · 54 °C/12 mmHg (lit.)
밀도: 1.096 g/mL · 1.096 g/mL at 25 °C (lit.)
굴절률: 20 · n20/D 1.457(lit.)
인화점: 118 °F · 118 °F
저장 조건: 2 · Keep in dark place,Inert atmosphere,2-8°C
물리적 상태: 액체
산도 계수 (pKa): 1 · pK1:7.95(SH) (25°C)
색상: 무색의
수용성: 물에 섞이거나 혼합하기 어렵지 않습니다.
BRN: 605581 · 605581
안정성: 안정적인. 가연성. 강한 산화제, 강한 염기와 호환되지 않습니다.
화장품 원료 기능: 피부의 산화 스트레스를 줄이세요제모제헤어 웨이브 또는 스트레이트
InChI: 1S/C4H8O2S/c1-2-6-4(5)3-7/h7H,2-3H2,1H3
InChIKey: PVBRSNZAOAJRKO-UHFFFAOYSA-N
SMILES: CCOC(=O)CS
LogP: 1.134 · 1.134 (est)
EPA: Acetic acid, mercapto-, ethyl ester (623-51-8)

화학적 성질

colourless liquid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H226 (98.1%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P264, P264+P265, P270, P280, P301+P316, P302+P352, P303+P361+P353, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 03-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/34481

Ethyl thioglycolate: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryA mild eye irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Thioglycolic acid.

Hazard Classes and CategoriesFlam. Liq. 3 (98.1%)

독성 정보

Toxicity Summary · 2건

Based on the available data, the CIR Expert Panel concluded that ... Ethyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure.

Safe for use in cosmetics, with qualifications

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: AI6650000
ridadr: UN 1992 3/PG 3
HS 번호: 29309090
risk_code: 10-25-36/38
hazard_code: T
safety_code: 26-36/37/39-45
포장분류: III
위험 등급: 3
기존화학 물질: KE-13895
Hazard Classifications: Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1STOT SE 3
스토리지 클래스: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

화학 및 산업

용도 및 제조

UsesCIR ingredient: Ethyl Thioglycolate

Use ClassificationCosmetics -> Hair waving or straightening; Reducing; Depilatory

General Manufacturing InformationAcetic acid, 2-mercapto-, ethyl ester: ACTIVE

응용 분야 · 1건

용도It finds its application in the reaction of the dilithio-derivative with an aldehyde, followed by conversion to the episulfide by reaction with ethyl chloroformate, and desulfurization with triethyl phosphite, leads to the (E)-2-alkenoic acid with high stereoselectivity. It is used as depilatories, hair straightening agent, hair waving agent, and reducing agent in cosmetic industry.

상·하류 제품 정보

상류 원료

티오글리콜산

하류 제품

Flomoxef ETHYL 6-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLATE RUFLOXACIN THIENO[3,2-D]PYRIMIDIN-4(3H)-ONE 6-클로로-1-벤조티오펜-2-카복실산 에틸6-브로모-1-벤조티오펜-2-카르복실레이트 아세트산 에틸3-아미노티오펜-2-카르복실레이트 로다닌-3-아세트산 4-Chlorothieno[3,2-d]pyrimidine Acetic acid, 2-(chlorosulfinyl)-, ethyl ester Methyl 4-[(2-ethoxy-2-oxoethyl)-thio]-3-nitrobenzoate

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

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上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

河北创海生物科技有限公司+86-86-13131129325 · [email protected]

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

연결된 노트

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에틸티오글라이콜레이트

기본 정보

개요