기본 정보
- CAS
84588-89-6- 표준 SMILES
NCCCC[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCC(=O)N1)C(=O)O- InChIKey
WMMKLGOAKIPZJN-YTFOTSKYSA-N- 분자식
- C23H36N6O11S
- 평균 분자량
- 604.6 g/mol
- 단동위원소 질량
- 604.21627716
개요
synthetic analog of granulocyte chalone; initially identified in extracts of rodent bone marrow and human leukocytes; monomer inhibits both formation of GM-CFC colonies and cytotoxic drug induced recruitment of murine CRU-S cells into active cell cycle; dimer has stimulatory activity
이름 및 식별자
- 우선 이름
- Hemoregulatory peptide 5b
- IUPAC
- (2S)-6-amino-2-[[(2R)-2-[[(2S)-3-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]butanoyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoic acid
- 현지명
- 혈액조절펩타이드5b
- 영어명
- hemoregulatory peptide 5b
- 분자식
- C23H36N6O11S
- 분자량
- 604.63
이름 및 동의어
hemoregulatory peptide 5bPeedckGlp-glu-asp-cys-lys-OHSP1 Pentapeptide84588-89-6Pglu-glu-asp-cys-lys-OHhp 5BPyroglutamyl-glutamyl-aspartyl-cysteinyl-lysineL-Lysine, N2-(N-(N-(N-(5-oxo-L-prolyl)-L-alpha-glutamyl)-L-alpha-aspartyl)-L-cysteinyl)-RefChem:145553pGlu-Glu-Asp-Cys-LyspyroGlu-Glu-Asp-Cys-Lys
이름 더 보기
혈액조절펩타이드5bpGlu-EDCKL-Lysine, 5-oxo-L-prolyl-L-α-glutamyl-L-α-aspartyl-L-cysteinyl-
(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]butanoyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoic acidorb1983752SCHEMBL10341273DTXSID701004874TP2340((S)-5-oxopyrrolidine-2-carbonyl)-L-glutamyl-L-aspartyl-L-cysteinyl-L-lysine(2S)-6-AMINO-2-[(2R)-2-[(2S)-3-CARBOXY-2-[(2S)-4-CARBOXY-2-{[(2S)-5-OXOPYRROLIDIN-2-YL]FORMAMIDO}BUTANAMIDO]PROPANAMIDO]-3-SULFANYLPROPANAMIDO]HEXANOIC ACIDN~2~-[(2R)-2-{[(2S)-3-Carboxy-2-{[(2S)-4-carboxy-1-hydroxy-2-({hydroxy[(2S)-5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl]methylidene}amino)butylidene]amino}-1-hydroxypropylidene]amino}-1-hydroxy-3-sulfanylpropylidene]-L-lysine
데이터베이스 식별자
물성
구조 계산 물성
- XLogP
- -5.8
- 극성 표면적
- 284 Ų
- 수소 결합 공여자 수
- 10
- 수소 결합 수용자 수
- 13
- 회전 가능 결합 수
- 19
- 무거운 원자 수
- 41
- 형식 전하
- 0
- 복잡도
- 1,010
화학 및 산업
약리 정보
MeSH Pharmacological ClassificationEndogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= PLANT GROWTH REGULATORS).
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