기본 정보
- CAS
120786-18-7- 표준 SMILES
CC=C1C2C=C(C)CC1(N)c1ccc(=O)[nH]c1C2- InChIKey
ZRJBHWIHUMBLCN-UHFFFAOYSA-N- 분자식
- C15H18N2O
- 평균 분자량
- 242.32 g/mol
- 단동위원소 질량
- 242.1419132
개요
LSM-1581 has been reported in Huperzia serrata with data available.
이름 및 식별자
- 우선 이름
- Acanthus ilicifolius Linn
- IUPAC
- 1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
- 영어명
- Huperzine A
- 분자식
- C15H18N2O
- 분자량
- 242.32
이름 및 동의어
Acanthus ilicifolius LinnRefChem:1075165(+/-)-Huperzine A120786-18-7Selagine1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-oneHupA(1R,9S,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one(-)-Huperzine A (HupA)103735-86-0HB0001(+/-)Huperzine A
이름 더 보기
HUPERAZINE AHUPERZINE A[+/-]-SELAGINE(+/-)-SELAGINE(±)-Huperzine A(+/-)-HuperzineA(+/-)-HUPERAZINE A(±)-Huperzine A, >98%
CBiol_001885BSPBio_001143KBioGR_000483KBioSS_000483SCHEMBL1047469CHEMBL3184073BDBM10441KBio2_000483
데이터베이스 식별자
- CAS
120786-18-7- PubChem CID
- 1253
- ChEMBL
CHEMBL3184073
물성
구조 계산 물성
- XLogP
- 0
- 극성 표면적
- 55.1 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 18
- 형식 전하
- 0
- 복잡도
- 551
물리화학적 성질
- 끓는 점
- 505 · 505.0±50.0 °C(Predicted)
- 밀도
- 1.2 · 1.20±0.1 g/cm3(Predicted)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 50 mg/mL · DMSO : ≥ 50 mg/mL (206.34 mM)
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 12.25 · 12.25±0.60(Predicted)
- 색상
- 흰색 또는 황백색
- InChI
- InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
- InChIKey
- ZRJBHWIHUMBLCN-QDEBKDIKSA-N
- SMILES
- C12CC3/C(=C\C)/C(N)(C=1C=CC(=O)N2)CC(C)=C3
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 3 (100%)
안전 데이터
- wgk
- 3
- rtecs
- PB9185700
- ridadr
- UN 1544 6.1/PG 2
- risk_code
- 23/24/25-36/37/38
- hazard_code
- T
- safety_code
- 26-36/37/39-45
화학 및 산업
응용 분야
개요Huperzine A is an alkaloid extract derived from the Chinese club moss Huperzia serrata. It is an acetylcholinesterase inhibitor. This means it helps promote higher levels of acetylcholine in the brain. Higher levels of acetylcholine support ones ability to perform cognitive tasks such as learning new things, memorizing information, and focusing at the task at hand. Huperzine A is considered to be a nootropic supplement because it supports cognitive function. It is considered a focus and memory nootropic similar to alpha gpc, bacopa, phosphatidylcholine, cdp choline, sulbutiamine, and uridine. It is also considered a brain booster as it is used for brain health and support.Huperzine A for many years has been widely used in traditional Chinese medicine to enhance memory and to treat fever and inflammation. In the United States it is commercially available as a food supplement, but has not been approved by the FDA as a treatment for AD or other cognition disorders.
출처Huperzine A is a synthetic.
용도Huperzine A is used for dementia in Alzheimer’s disease and for muscle weakness in myasthenia gravis.
상·하류 제품 정보
상류 원료
공급사100 곳
北京华美互利生物化工
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