기본 정보
- CAS
77727-17-4- 표준 SMILES
NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O- InChIKey
UEJYSALTSUZXFV-SRVKXCTJSA-N- 분자식
- C18H32N8O6
- 평균 분자량
- 456.5 g/mol
- 단동위원소 질량
- 456.24448077
개요
Rigin is an oligopeptide.
이름 및 식별자
- 우선 이름
- Rigin
- IUPAC
- (2S)-2-[[(2S)-1-[(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
- 현지명
- 테트라펩타이드-7
- 영어명
- Rigin
- 분자식
- C18H32N8O6
- 분자량
- 456.5
이름 및 동의어
Rigin77727-17-4Tetrapeptide-7Gly-gln-pro-argGQPRGly-Gln-Pro-Arg-OHGlycyl-L-glutaminyl-L-prolyl-L-arginineX519T00027DTXSID70228350L-Arginine, N2-(1-(N2-glycyl-L-glutaminyl)-L-prolyl)-(2S)-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid(2S)-2-(((2S)-1-((2S)-2-(2-aminoacetamido)-4-carbamoylbutanoyl)pyrrolidin-2-yl)formamido)-5-carbamimidamidopentanoic acid
이름 더 보기
테트라펩타이드-7DermaPep A410Rigin H-Gly-Gln-Pro-Arg-OHPalmitoyl Tetrapeptide-7, DermaPep A410, RegestrilPalmitoyl Tetrapeptide-3, Palmitoyl Tetrapeptide-7(2S)-2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-4-carbamoyl-butanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
RefChem:179448DTXCID90150841L-Arginine,glycyl-L-glutaminyl-L-prolyl-(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acidUNII-X519T00027SCHEMBL3829879SCHEMBL29089635CHEBI:171682
데이터베이스 식별자
- CAS
77727-17-4- PubChem CID
- 127555
- DTXSID
DTXSID70228350- ChEBI
CHEBI:171682- UNII
- X519T00027
- Nikkaji
- J557.453F
물성
구조 계산 물성
- XLogP
- -7.7
- 극성 표면적
- 249 Ų
- 수소 결합 공여자 수
- 7
- 수소 결합 수용자 수
- 8
- 회전 가능 결합 수
- 13
- 무거운 원자 수
- 32
- 형식 전하
- 0
- 복잡도
- 739
실험 및 물리화학적 성질
Physical DescriptionSolid
물리화학적 성질
- 밀도
- 1.57 · 1.57±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 3.6 · 3.60±0.21(Predicted)
- InChIKey
- UEJYSALTSUZXFV-SRVKXCTJSA-N
- SMILES
- C(O)(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)CN
화학 및 산업
응용 분야
개요Rigin is a tuftsin-like tetrapeptide with the sequence G-Q-P-R that is derived from IgG. Rigin exhibits immunomodulatory activity, stimulating phagocytosis, activating polymorphonuclear lymphocytes and macrophages, and protecting against stress-induced damage.
용도Rigin is a synthetic peptide that is a fragment of immunoglobulin G. It binds to palmitic acid, making it more lipophilic and thus enhancing its affinity for human skin. Rigin is the active ingredient in the drug MELAO MATRIXYL 3000 SERUM, which promotes the production of facial collagen. It is also used as a pharmaceutical intermediate for the preparation of biologically active drugs.
공급사41 곳
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd+86-13119157289 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Chengdu Youngshe Chemical Co., Ltd.+86-18108235634 · [email protected]
河北茹麒科技有限公司176-03256889 17603256889 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
LEON (NANJING) BIOTECHNOLOGY CO., LTD.15051830413 · [email protected]
石家庄赛鑫科技有限公司+86-16632312509 +86-16632315022 · [email protected]
康明永瑞生物科技（苏州）有限公司17751201929; 17751201929 · [email protected]
杭州专肽生物技术有限公司17342063383 · [email protected]
四川爱元生物医药科技有限公司0838-6510595 13402890778 15102836436 · [email protected]
陕西缔都医药化工有限公司+86-29-87569262 +86-15003564040 · [email protected]
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD+8613676922317 · [email protected]
杭州贝普泰生物医药有限公司0571-85350119 13305819357 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
杭州固拓生物科技有限公司0571-88211921 17357109671 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
南京肽谷生物科技有限公司18115476705 · [email protected]
南京莱昂生物科技有限公司025-84523390 -127; 17705183659 · [email protected]
成都云希化工有限公司+86-17380623303 · [email protected]
南京肽业生物科技有限公司025-58361106-805 15951641583 · [email protected]
江西辐氨生物技术有限公司15002819872 · [email protected]
career henan chemical co+86-0371-86658258 · [email protected]
河南阿尔法化工有限公司0371-55051623 18137891487 · [email protected]
浙江杰坤生物科技有限公司15397062932 · [email protected]
广州鑫研泽生物科技有限公司18120340188 · [email protected]
南京源肽生物科技有限公司13357818155 · [email protected]
江西研肽生物医药科技有限公司13758194781; 13758194781 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
ANHUI BYERSEN BIOTECH CO. LTD+8617355064950 · [email protected]
南京肽研生物科技有限公司19961912513 19941518170 · [email protected]
杭州拜格医药科技有限公司0571-85350119 15888826472 · [email protected]
广东翁江化学试剂有限公司0751-2815983 13927872582 · [email protected]
南昌探真生物技术有限公司13758194781 13173652190 · [email protected]
Nanjing TGpeptide+86-13347807150 · [email protected]
深圳利斯康医药科技有限公司+86-0755-89396905 +86-18025329037 · [email protected]
DONBOO AMINO ACID COMPANY13063595538 · [email protected]
广州奥司汀生物技术有限公司15918640830 13268843209 · [email protected]
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