기본 정보
- CAS
101141-95-1- 표준 SMILES
N[C@@H](Cc1ccc(OP(=O)(O)O)c(O)c1)C(=O)O- InChIKey
YNDMEEULGSTYJT-LURJTMIESA-N- 분자식
- C9H12NO7P
- 평균 분자량
- 277.17 g/mol
- 단동위원소 질량
- 277.03513835
개요
Foslevodopa is an L-tyrosine derivative that is L-dopa in which the hydroxy group at position 4' is replaced by a phosphonooxy group. It is a water-soluble prodrug of levodopa which is used for the treatment of Parkinson's disease. It has a role as an antiparkinson drug and a prodrug. It is an O-phosphoamino acid, a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid. It is functionally related to a L-dopa.
이름 및 식별자
- 우선 이름
- Foslevodopa
- IUPAC
- (2S)-2-amino-3-(3-hydroxy-4-phosphonooxyphenyl)propanoic acid
- 현지명
- DOPA4-인산염
- 영어명
- DOPA 4-phosphate
- 분자식
- C9H12NO7P
- 분자량
- 277.167841
이름 및 동의어
Foslevodopa97321-87-4Levodopa-4'-monophosphate3-hydroxy-O-phosphono-L-tyrosineFoslevodopa [USAN](2S)-2-amino-3-(3-hydroxy-4-phosphonooxyphenyl)propanoic acid37NQZ0J76IFOSLEVODOPA [INN]FOSLEVODOPA [JAN]ABBV-951 COMPONENT FOSLEVODOPAL-TYROSINE, 3-HYDROXY-O-PHOSPHONO-L-TYROSINE, 3-HYDROXY-, 4-(DIHYDROGEN PHOSPHATE)
이름 더 보기
DOPA4-인산염DOPA 4-PHOSPHONATE
foslevodopumRefChem:600352Dopa 4-phosphateABBV-951101141-95-1UNII-37NQZ0J76IWHO 11006(S)-2-amino-3-(3-hydroxy-4-(phosphonooxy)phenyl)propanoic acid
데이터베이스 식별자
- CAS
101141-95-1、97321-87-4- PubChem CID
- 127766
- DTXSID
DTXSID70905957- ChEMBL
CHEMBL4594379- ChEBI
CHEBI:192509- UNII
- 37NQZ0J76I
- Nikkaji
- J3.795.603A
물성
구조 계산 물성
- XLogP
- -4
- 극성 표면적
- 150 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 8
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 18
- 형식 전하
- 0
- 복잡도
- 344
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
화학 및 산업
공급사12 곳
上海沛灵生物科技有限公司13127581762 13127581762 · [email protected]
Hefei TianRui Pharmaceutical Chemical Co., Ltd.+86-0551-68665055 +86-+86-18616906106 · [email protected]
合肥天瑞药物化学有限公司0551-68933033 13956024211
Chongqing jooe co., ltd+86-15223382610 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
成都同创源医药科技有限公司028-83379370 13880556291 · [email protected]
上海康满林生物医药有限公司68080707 15021879576 · [email protected]
济南尚博医药股份有限公司0531-61320525 15866703830 · [email protected]
上海智乾生物科技有限公司[email protected]
济南尚博生物科技有限公司+8615866703830 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
南京沃格尼化工有限公司15996452985 · [email protected]
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