기본 정보
- 표준 SMILES
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[K+].[K+].[K+]- InChIKey
QEEAPRPFLLJWCF-UHFFFAOYSA-K- 분자식
- C6H5K3O7
- 평균 분자량
- 306.39 g/mol
- 단동위원소 질량
- 305.8946469
이름 및 식별자
- 우선 이름
- Tripotassium citrate
- IUPAC
- tripotassium;2-hydroxypropane-1,2,3-tricarboxylate
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
7778-49-6、866-84-2- PubChem CID
- 13344
- DTXSID
DTXSID8027325- ChEMBL
CHEMBL1200458- ChEBI
CHEBI:64733- UNII
- 86R1NVR0HW
- EC Number
- 212-755-5、231-905-0
- Nikkaji
- J7.148J
물성
구조 계산 물성
- 극성 표면적
- 141 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 2
- 무거운 원자 수
- 16
- 형식 전하
- 0
- 복잡도
- 211
실험 및 물리화학적 성질
pH
Between 7,5 and 9,0 (5 % aqueous solution)
THE AQ SOLN IS ALKALINE TO LITMUS; PH ABOUT 8.5
Color/Form
WHITE CRYSTALS, GRANULES, OR POWDER
TRANSPARENT CRYSTALS
Solubility
1 G DISSOLVES IN 0.65 ML WATER
1 G DISSOLVES VERY SLOWLY IN 2.5 ML GLYCEROL
ALMOST INSOL IN ALCOHOL
Physical Description
Liquid
Liquid; Large Crystals; Dry Powder
White, hygroscopic, granular powder or transparent crystals
Monohydrate: White odorless solid; [Merck Index] White odorless crystalline granules; [MSDSonline]
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 96.3% (572 of 594) of all reports.
Not Classified;Reported as not meeting GHS hazard criteria by 572 of 594 companies (only 3.7% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 594 reports by companies from 4 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 572 of 594 reports by companies.;There are 2 notifications provided by 22 of 594 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
This chemical does not meet GHS hazard criteria for 100% (14 of 14) of all reports.
Not Classified;Reported as not meeting GHS hazard criteria by 14 of 14 companies. For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 14 reports by companies from 2 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 14 of 14 reports by companies.;There are 0 notifications provided by 0 of 14 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
유해성 정보
Regulatory Information
Chemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:?) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:?) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 19-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14309
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Not Classified
Not Classified
안전 및 보호
Protective Action Criteria (PAC)
2.1 [mg/m3]
23 [mg/m3]
140 [mg/m3]
독성 정보
규제 정보
Regulatory Information
Chemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:?) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:?) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 19-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14309
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt: Does not have an individual approval but may be used under an appropriate group standard
화학 및 산업
약리 정보
FDA Pharmacological Classification
86R1NVR0HW
POTASSIUM CITRATE ANHYDROUS
Mechanisms of Action [MoA] - Alkalinizing Activity
Established Pharmacologic Class [EPC] - Metabolic Alkalinizer
Potassium citrate anhydrous is a Metabolic Alkalinizer. The mechanism of action of potassium citrate anhydrous is as an Alkalinizing Activity.
MeSH Pharmacological Classification
Agents that promote the excretion of urine through their effects on kidney function.
Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.
용도 및 제조
Uses
Used as a food additive (sequestrant, stabilizer, and buffer), a preservative for cut flowers, and a medication (potassium supplement, diuretic, expectorant, and alkalizer); [HSDB] Used as chemical intermediate; [MSDSonline]
MEDICATION
MEDICATION (VET)
SEQUESTRANT FOOD ADDITIVE
STABILIZER, BUFFER IN FOODS
IN PRESERVATION OF CUT FLOWERS
U.S. Production
2023: 75,000 - <100,000 lb;2022: 75,000 - <100,000 lb;2021: 75,000 - <100,000 lb;2020: 50,000 - <250,000 lb
2023: 1,000,000 - <2,500,000 lb;2022: 2,500,000 - <4,000,000 lb;2021: 2,500,000 - <4,000,000 lb;2020: 1,000,000 - <2,500,000 lb
Formulations/Preparations
POTASSIUM CITRATE, NF. POWDER, NF. TABLETS, 2.3 MEQ OF K+ AND 0.8 MEQ OF C6H5O7(3-) (250 MG), 2.8 MEQ OF K+ AND 0.9 MEQ OF C6H5O7(3-) (300 MG), AND 5.6 MEQ OF K+ AND 1.8 MEQ OF C6H5O7(3-) (600 MG).
IT IS AT LEAST 99% PURE.
GRADES: TECHNICAL; CP; NF; FCC.
Use Classification
EPA Safer Chemical Functional Use Classes -> Chelating Agents;Processing Aids and Additives
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Food additives
Fragrance Ingredients
Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; STABILIZER -> JECFA Functional Classes
Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT; STABILIZER -> JECFA Functional Classes
General Manufacturing Information
Other (requires additional information);Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing;Soap, Cleaning Compound, and Toilet Preparation Manufacturing
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3): ACTIVE
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:?): ACTIVE
INCOMPATIBILITIES: AQUEOUS SOLUTIONS...WILL REACT WITH ACIDIC SUBSTANCES. ALKALOIDAL SALTS MAY BE PPT FROM...AQ OR HYDROALCOHOLIC SOLN. ACIDIFICATION OR ADDITION OF ALCOHOL WILL RESTORE SOLN. CALCIUM & STRONTIUM SALTS CAUSE PRECIPITATION OF CORRESPONDING CITRATES.
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