2,2- 디플루오로에탄 -1- 아민

2,2-디플루오로에탄-1-아민 · 2,2-difluoroethanaMine · uoroethyL · CF2HCH2NH2 · AKOS B028561 · 2,2-Difluoroamine · Difluoroethylamine · ART-CHEM-BB B028561

https://huagongshe.com/ko/chemical/136274

식별자 및 물리적 특성

CAS No.	430-67-1
분자식	C2H5F2N
평균 분자량	81.06 g/mol
단동위원소 질량	81.0390056 g/mol
SMILES	NCC(F)F
InChIKey	OVRWUZYZECPJOB-UHFFFAOYSA-N
PubChem CID	136274
ChEMBL	CHEMBL1162281
EC No.	671-709-6
DTXSID	DTXSID40195621
현지명	2,2- 디플루오로에탄 -1- 아민

화학 및 물리적 성질

XLogP	0.1
극성 표면적	26
수소 결합 공여자 수	1
수소 결합 수용자 수	3
회전 가능 결합 수	1
무거운 원자 수	5
형식 전하	0
복잡도	21.6
SpringerMaterials Properties	Coriolis coupling
Dissociation Constants	7.3
끓는 점	67.5-68.5
밀도	1,15 g/cm3
증기압	14-56kPa at 20-50℃
굴절률	1.3410-1.3450
pKa(산도 계수)	7.09±0.30(Predicted)
물리적 상태	투명한 액체
색상	무색~황색
InChI	InChI=1S/C2H5F2N/c3-2(4)1-5/h2H,1,5H2
InChIKey	OVRWUZYZECPJOB-UHFFFAOYSA-N
SMILES	C(N)C(F)F

화학적 성질

Liquid

안전 및 규제

GHS 분류	DangerH290 (52.6%): May be corrosive to metals [Warning Corrosive to Metals]P234, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P337+P317, P363, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 76 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보	Status: Active Update: 08-12-2014 https://echa.europa.eu/registration-dossier/-/registered-dossier/5753
Hazard Classes and Categories	Met. Corr. 1 (52.6%)
수질 위해 등급(WGK)	WGK 3
운송 번호(UN)	2735
관세 코드	29211990
위험 문구(R)	34-36/37
위험 표시	C,Xi
안전 문구(S)	26-36/37/39-24/25
포장분류	II
위험 등급	IRRITANTEye Irrit. 2Met. Corr. 1STOT SE 3
저장 분류	8A - Combustible corrosive hazardous materials

용도

2,2-Difluoroethylamine (DFEA) is an ESI-compatible buffering reagent whose conjugate acid has a pKa of 7.2, providing buffering capacity at physiological pH[1]. 2,2-Difluoroethylamine serves as a nucleophile in Ni-catalyzed C–N cross-couplings with aryl electrophiles, including N-arylation of fluoroalkylamines and competition studies against other heteroatom-containing nucleophiles[2].