오메토산

Biological Exposure Indices (BEI) [ACGIH] - Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, carbon dioxide or dry chemical. /Organophosphorus pesticides, liquid, NOS/

If material on fire or involved in fire: Use water in flooding quantities as fog. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use "alcohol" foam, carbon dioxide or dry chemical. /Organophosphorus pesticides, solid, NOS/

Rooms used for storage only should be soundly constructed & fitted with secure locks. Floors should be kept clear & pesticides clearly identified. If repacking is carried out in storage rooms, adequate light should be available; floors should be impervious & sound ... . /Pesticides/

Pesticides containers must be provided with labels indicating the degree of toxicity of the product they contain. The labels must not only give a short description of how to use the prepn, but also state basic precautions to be taken when applying it. /Organophosphorus pesticides/

Pesticides of any degree of toxicity should be transported in containers which are clearly labelled, leak-proof, and not easily damaged. They should never be transported /or stored/ beside, or above any type of food, and all spillages should be immediately reported. /Pesticides/

Environmental considerations- land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. /Organophosphorus pesticides, liquid and solid, NOS/

Environmental considerations- water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses. /Organophosphorus pesticides, liquid and solid, NOS/

Environmental considerations- air spill: Apply water spray or mist to knock down vapors. /Organophosphorus pesticides, liquid and solid, NOS/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

All organic pesticides, whether of botanical or synthetic origin, can be destroyed by incineration. /Organic pesticides/

Manufacturers or formulators of very large amounts of pesticides may find it advantageous to build incinerators adequate to destroy all organic pesticides and equipped with scrubbers to remove acid wastes. /Organic pesticides/

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

In some situations where personnel may become accidently contaminated ... it is necessary to provide shower bath in addition to the usual washing facilities. Special arrangements for cleaning clothing & overalls may be necessary ... /Pesticides/

Special aircraft should preferably be used for spraying or dusting toxic organophosphorus pesticides. ... aerial spraying or dusting gives rise to clouds which spread over larger surfaces than clouds produced by ground application. Aerial spraying should therefore be carried out on windless days only. Residential areas, water supply sources, etc must be avoided. ... When aircraft approaches, signalmen /guiding the aircraft/ should leave the windward side. ... The local population should be informed about the site & time of aerial pesticide treatment. Access of unauthorized persons & especially children to the area to be treated must be ... forbidden. Warning signs should be placed at the limits of the area. Ground spraying must be carried out with compressed-air spraying equipment towed by tractors with closed cabs. /Organophosphorus pesticides/

Small packages of pesticides are preferable for individual application in order to limit the quantities to be weighed & metered. A special vessel with long stirring rod for dilution & suspension of the poison must be available in order to reduce manual handling to a minimum. The strict observance of hygiene rules--no smoking & no food intake during work. Thorough washing with soap after work, changing protective clothing before going home--is of utmost importance. /Organophosphorus pesticides/

For more Preventive Measures (Complete) data for OMETHOATE (14 total), please visit the HSDB record page.

Tolerances are established for total residues of the insecticide dimethoate (O,O-dimethyl S-(N-methylcarbamoylmethyl) phosphorodithioate) including its oxygen analog (O,O-dimethyl S-(N-methylcarbamoylmethyl) phosphorothioate) in or on the following raw agricultural commodities: [Table#6213]

Tolerances with regional registration, as defined in 180.1(n), are established for total residues of dimethoate including its oxygen analog in or on the following food commodities: asparagus 0.15 ppm; Brussels sprouts 5 ppm; and cherries 2 ppm.

Respiratory protection (supplied-air respirator with full facepiece or self-contained breathing apparatus) should be available where these compounds are manufactured or used and should be worn in case of emergency and overexposure. /Phosphorus compounds/

Workers handling and applying organophosphate pesticides (opp) must ... Be given personal protective equipment comprising overalls made of a tight fabric or polyvinyl chloride, gloves, and rubber boots. They must wear a respirator with an activated-carbon gas filter cartridge affording protection for a determined number of working hours. The eyes should be protected by goggles. The signalmen for aerial dusting operations should be equipped with a hat and cape made of polyvinyl chloride or a fabric impregnated with a water repellent. /Pesticides, organophosphorus/

Personnel protection ... Wear appropriate chemical protective gloves, boots and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. /Organophosphorus pesticides, liquid, flammable, toxic/

Personnel protection: ... Wear positive pressure self-contained breathing apparatus. ... Wear appropriate chemical protective clothing. /Organophosphorus pesticides, liquid and solid, NOS/

Anticholinesterase (organophosphorus) insecticides antagonize polarizing muscle relaxants. Phenothiazines /and thioxanthenes/: ... May enhance toxic effects of organophosphorus insecticides. /Insecticides, organophosphorus/

In long term therapy, adrenocorticoids antagonize the antiglaucoma effects of anticholinesterases (incr ocular pressure). ... Anticholinergics antagonize the miotic (antiglaucoma) & other muscarinic effects of anticholinesterases on the autonomic & central nervous systems. Tricyclic antidepressants (anticholinergic effects) antagonize the antiglaucoma (miotic) effects of anticholinesterases in glaucoma. ... Antihistamines with anticholinergic effects antagonize the miotic (antiglaucoma) & CNS effects of anticholinesterases. Anticholinesterases potentiate tranquilizing & behavioral changes induced by antihistamines. The actions of anticholinesterase agents on autonomic effector cells, & to some extent those on CNS, are antagonized by atropine, an antidote of choice. Barbiturates are potentiated by anticholinesterases. ... Dexpanthenol potentiates the effects of anticholinesterases. Fluorophosphate insecticides potentiate the effects of other anticholinesterases. /Anticholinesterases/

...To examine the therapeutic effect of combined use of obidoxime and atropine with artificial ventilation on respiratory muscle paralysis caused by omethoate poisoning... rats were exposed to 2 times the dose of LD50 omethoate and treated with atropine (10 mg/kg) to counteract cholinergic symptoms. When the rats' respiratory frequency became slower and /breathing labored/, trachea intubation and artificial ventilation was carried out. The rats in group A were continuously treated with atropine. The dose of obidoxime for Group B, C and D were 8, 15, 20 mg/kg respectively, given at the same time as artificial ventilation and 1, 2, 3 hours later. The doses of atropine was reduced to 1/3 - 2/3 of the first dose so as to maintain the rats atropinized. If the rat survival was beyond 60 minutes after withdrawal of artificial ventilation, the combined treatment was considered successful. The function of isolated phrenic diaphragm of the rats was observed with MS-302 physiological and pharmacological analysis instrument. None of the rats in Group A was successful after withdrawal from artificial ventilation and the function of phrenic diaphragm appeared poor; whereas >80% of the rats in B, C, D Group were successful after withdrawal from artificial ventilation in 3 hr and the function of phrenic diaphragm remained well. The survival rate in B, C and D groups were higher after withdrawal from artificial ventilation than that in Group A(P<0.01). The function of phrenic diaphragm in Group B, C and D were gradually decreased after ACh was added into the container. /The authors concluded that/ combined use of suitable dose of obidoxime and atropine with artificial ventilation for respiratory muscle paralysis caused by omethoate poisoning could promote the recovery of diaphragm function and reduce the death rate in poisoned rats.

Barbiturates are potentiated by anticholinesterases. Although barbiturates may be used cautiously in treating convulsions, extreme care is essential in handling poisonings due to anticholinesterases, particularly organophosphorus pesticides. Echothiophate, a cholinesterase inhibitor used as miotic, potentiates other such inhibitors ... Used for other purposes (additive effects) or possibly synergistic. Those exposed to organophosphate insecticides must take strict precautions. ... Organophosphorus insecticides: additive anticholinesterase effects. Hazardous. Patients on anticholinesterases (even topical, such as eye drops) should avoid areas where organophosphorus insecticides ...recently ...used. /Anticholinesterase/

LC50 Goldfish 10-100 mg/L/96 hr /Conditions of bioassay not specified/

LD50 Male Japanese quail acute oral 79.7 mg/kg

LD50 Female Japanese quail acute oral 83.4 mg/kg

LC50; Species: Daphnia magna (Water flea); Conditions: freshwater; renewal, 19 °C, pH 7.9, hardness 98.45 mg/L CaCO3, dissolved oxygen >6.5 mg/L; Concentration: 4.2 ug/L for 26 days /96.3% formulated product/

For more Ecotoxicity Values (Complete) data for OMETHOATE (16 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 9.4(SRC), determined from a log Kow of -0.74(2) and a regression-derived equation(3), indicates that omethoate is expected to have very high mobility in soil(SRC). Volatilization of omethoate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.6X10-14 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Omethoate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 2.48X10-5 mm Hg(2). Biodegradation in soil may be an important fate process in soil based on rapid rates for analogous dimethoate(SRC); dimethoate exhibited 77% degradation in clay loam soil in 2 wks compared to 18 and 20% degradation in the same soil that had been autoclaved or irradiated(5).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 9.4(SRC), determined from a log Kow of -0.74(2) and a regression-derived equation(3), indicates that omethoate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 4.6X10-14 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Omethoate undergoes 50% decomposition in 26 days by hydrolysis in water at 24 °C and pH 7(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). By analogy to dimethoate, which exhibited half-lives of 171, 173 and 219 days for river water, filtered river water and sea water, respectively(8), biodegradation of omethoate in water may be an important environmental fate process(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), omethoate, which has a vapor pressure of 2.48X10-5 mm Hg at 20 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase omethoate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 15 hours(SRC), calculated from its rate constant of 2.6X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase omethoate may be removed from the air by wet or dry deposition(SRC).

The Food and Drug Administration's (FDA) Los Angeles District Laboratory analyzed 6,391 domestic agricultural commodities during surveillance sampling for the period 10/81 to 9/86(1). The percentage of domestic commodities with omethoate concentrations in the 0.05, 0.1, 0.5, 1.0, and 2.0 ppm ranges were 3.7, 1.2, 1.4, 0.06, and 0.03%, respectively(1). The Food and Drug Administration's (FDA) Los Angeles District Laboratory analyzed 12,044 imported agricultural commodities during surveillance sampling for the period 10/81 to 9/86(1). The percentage of imported commodities with omethoate concentrations in the 0.05, 0.1, 0.5, 1.0, 2.0, and >2.0 ppm ranges were 1.6, 0.9, 1.2, 0.1, 0.06 and 0.04%, respectively(1). Omethoate was not detected in canned peaches from the 1999 season or fresh peaches form 8/2000 in 210 samples from Imathia and Pella, Greece(2). In a 1995 monitoring program in Egypt omethoate was not detected in cauliflower, carrot, courgette, cucumber, eggplant, cantaloupe, guava, mango, orange, or strawberry(3). Omethoate was found in cabbage, green beans, green peas, lettuce, tomato, apple grape and peach in the same 1995 monitoring program(3). In a 1996 monitoring program in Egypt omethoate was not detected in cabbage, melokhia, lettuce, watercress, artichoke, board bean, cauliflower, cantaloupe, cucumber, okra, onion, pepper, squash, tomato, carrot, sweet potato, taro, apple, apricot, mango, orange, pear, plum, pomegranate or strawberry(4). Omethoate was found in grape leaf, spinach, eggplant, green bean, green pea and peach in the same 1996 monitoring program(4). Omethoate was not detected in grapefruit, lemon, mandarin/clementine, orange, apple, pear, apricot, cherries, peach, nectarine, plum, grape, strawberry, blackberry, boysenberry, elderberry, raspberry, rowanberry, bilberry, red current, black current, gooseberry, banana, fig, pomegranate, beetroot, carrot, celeriac, horseradish, parsnip, parsley root, radish, garlic, onion, spring onion, tomato, pepper, eggplant, cucumber, melon, watermelon, squash, sweet corn, broccoli, cauliflower, brussels sprout, white cabbage, red cabbage, spring cabbage, oxheart cabbage, Chinese cabbage, kale, lettuce, spinach, chive, dill, marjoram, oregano, parsley, rosemary, thyme, bean, pea, celery, leek, rhubarb, mushroom, sunflower seed, or potato in the 1995-1996 Danish national pesticide monitoring program(5).

Using monitoring data from the FDA's Market Basket Survey during the period of 1982-1984, the average daily intake of omethoate in 6-11 month old infants, 2 year old toddlers, 14-16 year old females, 14-16 year old males, 25-30 year old females, 25-30 year old males, 60-65 year old females, and 60-65 year old males, was 1.8, 2.4, 1.8, 1.2, 4.4, 3.3, 4.6, and 4.0 ng/kg-body weight/day, respectively(1).

/AQUATIC SPECIES/ The acute toxicities of two organophosphorodithioate (dimethoate and disulfoton) and two organophosphorothioate (omethoate and demeton-S-methyl) insecticides were evaluated individually and in binary combination with the herbicide atrazine using fourth-instar larvae of the aquatic midge, Chironomus tentans. Atrazine alone up to 1,000 ug/L did not show significant toxicity to the midges in a 48-hr bioassay. However, atrazine concentrations as low as 1 ug/L in combination with dimethoate at EC25 (concentration to affect 25% of tested midges), 100 ug/L in combination with disulfoton (EC25), and 10 ug/L in combination with demeton-S-methyl (EC25) significantly enhanced the toxicity of each organophosphate insecticide. In contrast, atrazine concentrations of 10 ug/L and above in combination with omethoate (EC25) significantly decreased the toxicity of the insecticide. Biochemical analysis indicated that increased toxicity of dimethoate, disulfoton, and demeton-S-methyl in binary combination with atrazine correlated to the increased inhibition of acetylcholinesterase. Furthermore, cytochrome P450-dependent O-deethylation activity in the midges exposed to atrazine at 1,000 ug/L was 1.5-fold higher than that in the control midges. Thus, atrazine appeared to induce cytochrome P450 monooxygenases in the midges. Elevated cytochrome P450 monooxygenase activity may increase the toxicities of dimethoate, disulfoton, and demeton-S-methyl by enhancing the oxidative activation of dimethoate into omethoate, and disulfoton and demeton-S-methyl into their sulfoxide analogs with increased anticholinesterase activity. In contrast, atrazine reduced the toxicity of omethoate possibly by enhancing the oxidative metabolic detoxification since omethoate does not require oxidative activation.

/OTHER TERRESTRIAL SPECIES/ The actions on the honeybees of the insecticide-acaricides azinphos-methyl and omethoate, the insecticide diazinon, were investigated by ingestion and indirect contact in laboratory tests. The results of the trials revealed that the organophosphates azinphos-methyl, omethoate, and diazinon were highly toxic by ingestion and contact. Due to their high toxicity even at doses many times lower than those suggested for crop treatments, the organophosphorus compounds azinphos-methyl, omethoate, diazinon, and the heterocyclic dicarbonitrile dithianon appeared very dangerous to foraging and pollinating honeybees.

Workers handling & applying pesticides must undergo an annual medical examination at the beginning of each agricultural season. Contraindications for work with /organophosphorus pesticides/ are organic diseases of the central nervous system, mental disorders & epilepsy, pronounced endocrine & vegetative disorders, pulmonary tuberculosis, bronchial asthma, chronic respiratory diseases, cardiovascular diseases & circulatory disorders, gastrointestinal diseases (peptic ulcer), gastroenterocolitis, diseases of liver & kidneys, eye diseases (chronic conjunctivitis & keratitis). The blood cholinesterase activity must be determined before work starts. In the event of prolonged work periods, this activity should be determined at intervals of 3-4 days. Persons exhibiting a fall in cholinesterase activity of 25% or more must be transferred to other work where they are not exposed to organophosphorus pesticides until this activity is completely restored. Persons with initial signs of indisposition should cease work with pesticides. /Organophosphorus pesticides/

A final diagnosis of mild to moderate acute organophosphate pesticide poisoning is rarely justified unless all of the following five conditions are present: 1. A definite history of exposure to an organophosphate pesticide. 2. A latent interval of not more than a few hours between that last exposure and the onset of illness. 3. A clinical picture in which most or all of the following signs or symptoms are present: headache, blurred vision, weakness, tightness in chest, and constricted pupils. 4. Reduction of plasma and RBC cholinesterase activity to a level substantially below 50% of baseline values. Because of the wide normal range of RBC cholinesterase in the population, symptoms may be present with reported "normal" levels. 5. An acute illness that is not substantially longer than 48 hours. The classic presentation for acute organophosphate toxicity includes history, evidence of exposure to organophosphate (garlic odor), signs/symptoms of cholinergic excess, improvement with atropine or pralidoxime, and inhibition of cholinesterase in blood. /Organophosphate pesticide poisoning/

The assessment of exposure to the organophosphate pesticides, bromophos and dicrotophos can be accomplished through measurement of these compounds in the blood. However, since organophosphate pesticides are rapidly cleared from the blood, it is difficult to be able to detect the pesticides in blood unless very large quantities have been absorbed. This test may be useful for identification of the compound in cases of severe exposure, although documented tests for measurement of specific organophosphate pesticides in blood are very limited. Whole Blood Reference Ranges: Normal - none detected; Exposed - not established; Toxic -not established. Serum or Plasma Reference Ranges: Normal - not established; Exposed - not established; Toxic - not established. Urine Reference Ranges: Normal - not established; Exposed - not established; Toxic - not established. /Organophosphate pesticides/

The Koc of omethoate is estimated as 9.4(SRC), using a log Kow of -0.74(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that omethoate is expected to have very high mobility in soil(SRC). Aged leaching studies revealed that metabolites have only a low leaching potential(1).

Dimethoxon (CAS # 1113-02-6) was evaluated for acute oral toxicity in groups of fasted Wistar albino rats (15/sex/group) administered single doses of 0, 5, 10, 20, 22,5, 25, 30, 35, and 50 mg/kg bodyweight by oral gavage. Mortality from 18 minutes to 24 hours post-treatment was consistent with oral LD50's of 27.3 and 25.6 mg/kg, respectively, for male and female rats, based on probit analysis of Fink and Hund and 7-day post-treatment observation. Treated rats exhibited general behavioral disturbances (unspecified), dyspnea, and cholinergic effects from 5 to 25 minutes post-gavage, which persisted among survivors for up to 1 day, 1-3 days, and 3-6 days, respectively. In adjunctive study, the specific influence (doses unspecified) of dimethoxon (CAS # 1113-02-6) on cholinesterase was assessed in groups of female rats (15/group) receiving gavage doses of 0.3, 0.6, 1.3, 2.6, 7.7, and 17.8 mg/kg bodyweight. The effects on cholinesterase levels of brain, plasma, and erythrocytes were determined in 3 rats of each dose group at 0, 2, 5, 24, and 72 hours post-treatment. At sublethal doses from 1.3-17.7 mg/kg bodyweight, the anti-cholinergic effect was characterized by transient, but significant, inhibition of acetylcholinesterase of all tested samples. No such enzymatic response relative to controls was noted at doses below 1.3 mg/kg bodyweight. General behavioral disturbances (unspecified), with increased secretions, labored breathing, muscle tremors, and tonic and clonic convulsions were observed in association with the 2 highest doses. Earlier corroborative studies were also included with this submission.

The specific influence (doses unspecified) of dimethoxon (CAS # 1113-02-6) on cholinesterase was assessed in groups of female rats (15/group) receiving gavage doses of 0.3, 0.6, 1.3, 2.6, 7.7, and 17.8 mg/kg bodyweight. The effects on cholinesterase levels of brain, plasma, and erythrocytes were determined by a modified method of Ellmann in 3 rats of each dose group, respectively, at 0, 2, 5, 24, and 72 hours post-treatment. At sublethal doses from 1.3-17.7 mg/kg bodyweight, the anti-cholinergic effect was characterized by mild inhibition of acetylcholinesterase of the erythrocytes, and moderate to severe dose-related, transient inhibition of brain and plasma cholinesterase. No such enzymatic response relative to controls was noted at doses below 1.3 mg/kg bodyweight. General behavioral disturbances (unspecified), with increased secretions, labored breathing, muscle tremors, and tonic and clonic convulsions were also observed in association with the 2 highest doses. Cholinesterase levels returned to normal by Day 7 of 14-day post-gavage observation. Earlier corroborative studies were also included with this submission.

Dimethoxon (CAS # 1113-02-6) was evaluated for acute dermal toxicity in groups of Wistar albino rats (10/sex/group) administered single undiluted applications of 100, 500, 750, 1000, and 1500 ug/kg bodyweight upon occluded, clipped and intact skin of the back for 24 hours. Additional groups of 10 males received doses of 850 and 1250 mg/kg bodyweight, while a female group of 10 also received a dose of 900 mg/kg bodyweight. Mortality from Day 1 to Day 6 was consistent with dermal LD50's, by probit method of Fink and Hund and based on 14-day post-treatment observation, of 1018 and 865 mg/kg bodyweight for male and female rats, respectively. Rats at all dose levels exhibited clinical signs of toxicity, including behavioral disturbances (unspecified), dyspnea, and cholinergic symptoms, of 2-10, 2-6, and 2-3 days' duration, respectively. Earlier corroborative studies were also included with this submission.

Tolerances are established for total residues of the insecticide dimethoate (O,O-dimethyl S-(N-methylcarbamoylmethyl) phosphorodithioate) including its oxygen analog (O,O-dimethyl S-(N-methylcarbamoylmethyl) phosphorothioate) in or on the following raw agricultural commodities: [Table#6214]

Tolerances with regional registration, as defined in 180.1(n), are established for total residues of dimethoate including its oxygen analog in or on the following food commodities: asparagus; Brussels sprouts; and cherries.

This chemical ingredient is not found in any products. [NPIRS] The major metabolite of dimethoate; Has been used as an insecticide in vegetable and forage crops to control aphids and red spider mites; Has active international registrations; [HSDB]

Not registered for use in the US, but has active registrations internationally; [Reference #1]

Farming (Pesticides) [Category: Industry]

ANNEX VIII: Pesticides which shall not be used in agricultural production intended for the production of processed cerealbased foods and baby foods - omethoate /From table/

Omethoate, the major toxic degradate of dimethoate, is registered as an active ingredient internationally, but not in the United States.

Insecticide used extensively in vegetable and forage crop production /Dimethoate/

Omethoate is produced by reaction of O,O-dimethylphosphorylmercaptoacetic acid with methyl isocyanate

Omethoate may be prepared by the reaction of O,O-dimethylphosphorothioic acid with 2-chloro-N-methylacetamide.

Aerosol dispenser; emulsifiable concentrate; soluble concentrate; ultra-low volume liquid

Mixtures: (omethoate+) tetradifon; dicofol + tetradifon; cyfluthrin

...Technical omethoate has the following composition: Omethoate min 94.5%, O-desmethyl-omethoate max 2.0%, Dimethyl phosphite max 2.0%, Solvents max 2.0%.

Transformation products, Acaricides, Insecticides

Environmental transformation -> Pesticide transformation products (metabolite, successor)

The WHO Recommended Classification of Pesticides by Hazard identifies Omethoate (technical grade) as Class IB: highly hazardous; Main Use: insecticide.

Not registered for use in U.S.

P-O analogue of dimethoate