Dimethylthexylsilyl chloride
TDSCL · Chloro(dimethyl)thexylsilane 95% · Chloro(2,3-diMethylbutan-2-yl)diMethylsilane · TDSCI · DK359 · THEXYLDIMETHYLCHLOROSILANE · Thexyldimethylsilylchlorid · Chlorothexyldimethylsilane
식별자 및 물리적 특성
| CAS No. | 67373-56-2 |
|---|---|
| 분자식 | C8H19ClSi |
| 평균 분자량 | 178.77 g/mol |
| 단동위원소 질량 | 178.09445482 g/mol |
| SMILES | CC(C)C(C)(C)[Si](C)(C)Cl |
| InChIKey | KIGALSBMRYYLFJ-UHFFFAOYSA-N |
| PubChem CID | 144239 |
| EC No. | 629-449-6 |
| DTXSID | DTXSID70217729 |
화학 및 물리적 성질
| 극성 표면적 | 0 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 0 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 116 |
| SpringerMaterials Properties | 29Si nuclear magnetic resonance spectrum |
| 녹는점 | 15 °C |
| 끓는 점 | 55-56 °C10 mm Hg(lit.) |
| 밀도 | 0.909 g/mL at 25 °C(lit.) |
| 굴절률 | n20/D 1.449(lit.) |
| 인화점 | 125 °F |
| 저장 조건 | Sealed in dry,2-8°C |
| 용해도 | THF, DMF, CH2Cl2에 용해됨 |
| 물리적 상태 | 투명한 액체 |
| 색상 | 무색 내지 거의 무색 |
| 비중 | 0.911 |
| BRN | 3647960 |
| InChI | 1S/C8H19ClSi/c1-7(2)8(3,4)10(5,6)9/h7H,1-6H3 |
| InChIKey | KIGALSBMRYYLFJ-UHFFFAOYSA-N |
| SMILES | CC(C)C(C)(C)[Si](C)(C)Cl |
화학적 성질
clear colorless to almost colorless liquid
안전 및 규제
| GHS 분류 | DangerH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 44 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Silane, chlorodimethyl(1,1,2-trimethylpropyl)-: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 3 (100%) |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | No |
| 운송 번호(UN) | UN 2986 8/PG 2 |
| 관세 코드 | 29319090 |
| 위험 문구(R) | 10-34-37 |
| 위험 표시 | C |
| 안전 문구(S) | 26-36/37/39-45 |
| 포장분류 | II |
| 위험 등급 | 8Flam. Liq. 3Skin Corr. 1B |
| F 고인화성물질 | 10-21 |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Silylating reagent for the protection of 1 and 2 alcohols and N-silylation of amines and amides; used in the preparation of thexyldimethylsilyl triflate; formation of α-silyl hydrazones; formylation of polyfluoroalkyl halides. Thexyldimethylsilyl chloride (TDS-Cl) was first introduced as a more easily prepared alternative to the more commonly used t-butyldimethylsilyl chloride for the protection of alcohols.
제조 및 합성 방법
제조 방법
To a mixture of dimethylchlorosilane (10 mL, 92 mmol) and AlCl3 (0.680 g, 5 mmol) at 25°Cwas added 2,3-dimethyl-2-butene (11 mL, 91 mmol). After stirring for 4 h at ambient temperature, the mixture was filtered and distilled to yield 15.2 g of TDS-Cl (93%).