라미프릴디케토피페라진

Ramipril diketopiperazine

HCID 14520363

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 108731-95-9
표준 SMILES: CCOC(=O)[C@H](CCc1ccccc1)N1C(=O)[C@@H]2C[C@@H]3CCC[C@@H]3N2C(=O)[C@@H]1C
InChIKey: KOVMAAYRBJCASY-JBDAPHQKSA-N
분자식: C23H30N2O4
평균 분자량: 398.5 g/mol
단동위원소 질량: 398.22055744

이름 및 식별자

우선 이름: Ramipril diketopiperazine
IUPAC: ethyl (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoate
현지명: 라미프릴디케토피페라진
영어명: Ramipril Diketopiperazine
분자식: C23H30N2O4
분자량: 398.5

이름 및 동의어

Ramipril Diketopiperazine108731-95-9Ramipril-diketopiperazineUNII-U3O93H26WIU3O93H26WIRamipril specified impurity D [EP]Ethyl (2S)-2-((3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta(4,5)pyrrolo(1,2-a)pyrazin-2-yl)-4-phenylbutanoateRAMIPRIL IMPURITY D [EP IMPURITY]2H-Cyclopenta(4,5)pyrrolo(1,2-a)pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-, ethyl ester, (alphaS,3S,5aS,8aS,9aS)-2H-CYCLOPENTA(4,5)PYRROLO(1,2-A)PYRAZINE-2-ACETIC ACID, DECAHYDRO-3-METHYL-1,4-DIOXO-.ALPHA.-(2-PHENYLETHYL)-, ETHYL ESTER, (.ALPHA.S,3S,5AS,8AS,9AS)-RAMIPRIL IMPURITY D (EP IMPURITY)Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate

이름 더 보기

라미프릴디케토피페라진Ramipril EP Imp DRamipril Impurity 32Ramipril EP Imurity DRaMipril IMpurity-D (EP)Ramipril impurity D (R0145020)Ramipril USP Related Compound DRamipril Related Compound D/EP impurity DRamipril diketopiperazine (EP Impurity D)

RefChem:202838Ramipril specified impurity DRamipril EP Impurity Dethyl (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoateRamipril impurityEthyl (2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenyl butanoateEthyl (2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate (Ramipril Diketopiperazine)Ramipril impurity D CRS

데이터베이스 식별자

CAS: 108731-95-9
PubChem CID: 14520363
DTXSID: DTXSID001312563
UNII: U3O93H26WI
EC Number: 642-122-2
Nikkaji: J1.380.340D

물성

구조 계산 물성

XLogP: 3.4
극성 표면적: 66.9 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 7
무거운 원자 수: 29
형식 전하: 0
복잡도: 645

물리화학적 성질

끓는 점: 597.4 · 597.4±50.0 °C(Predicted)
밀도: 1.22 · 1.22±0.1 g/cm3(Predicted)
저장 조건: 2 · 2-8°C
용해도: DMSO: soluble,Ethanol: soluble
산도 계수 (pKa): -1.16 · -1.16±0.40(Predicted)
안정성: 흡습성
주요 응용: 제약
InChIKey: KOVMAAYRBJCASY-JBDAPHQKSA-N
SMILES: N21[C@@H]3[C@H](C[C@H]2C(=O)N([C@H](C1=O)C)[C@@H](CCc4ccccc4)C(=O)OCC)CCC3

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (100%)

안전 데이터

wgk: WGK 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

Tissue LocationsKidney

Cellular LocationsCytoplasm

응용 분야

용도Ramipril Diketopiperazine (Ramipril EP Impurity D) is a metabolite of Ramipril (R111000).

공급사48 곳

上海策嵘生物科技有限公司[email protected]

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]

济南百隆化学有限公司[email protected] · [email protected]

成都超九八生物科技有限公司13348960310 13348960310 · [email protected]

艾吉析科技（上海）有限公司17717235263 · [email protected]

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