기본 정보
- CAS
127-35-5- 표준 SMILES
CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1- InChIKey
ZQHYKVKNPWDQSL-UHFFFAOYSA-N- 분자식
- C22H27NO
- 평균 분자량
- 321.5 g/mol
- 단동위원소 질량
- 321.20926449
개요
Phenazocine is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence. It is a Opiates substance.
이름 및 식별자
- 우선 이름
- Phenazocine
- IUPAC
- 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
- 현지명
- 페나조신
- 영어명
- phenazocine
- 분자식
- C22H27NO
- 분자량
- 321.46
이름 및 동의어
PHENAZOCINEPhenethylazocineFenazocinaPhenobenzorphanPhenazocinum127-35-52,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-IDS-NP-008DTXSID908607362'-Hydroxy-5,9-dimethyl-2-phenethyl-6,7-benzomorphanHydrobromide, PhenazocinePhenbenzorphan
이름 더 보기
페나조신SKF-6574PrinadolZQHYKVKNPWDQSL-NKDCDXMNSA-N1,2,3,4,5,6-Hexahydro-6,11-diMethyl-3-phenethyl-2,6-Methano-3-benzazocin-8-ol1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol
J0ND6N0AQCCHEBI:8056RefChem:172642DTXCID20197320N02AD021,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo(7.3.1.02,7)trideca-2(7),3,5-trien-4-ol204-835-3NIH 7519
데이터베이스 식별자
- CAS
127-35-5、58073-76-0- PubChem CID
- 14707
물성
구조 계산 물성
- XLogP
- 3.8
- 극성 표면적
- 23.5 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 432
실험 및 물리화학적 성질
Drugs
DEA NFLIS-Drug Category -> Narcotic Analgesics
DEA Schedule II Controlled Substance -> Opiates
Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
Human DrugsPharmaceuticals
Endocrine DisruptorsPotential endocrine disrupting compound
물리화학적 성질
- 녹는점
- 181 °C · 181 °C
- 끓는 점
- 460.995 · 460.995±45.00 °C(Press: 760.00 Torr)(predicted)
- 밀도
- 1.097 · 1.097±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- 산도 계수 (pKa)
- 8.5 · pKa 8.50(50% aq EtOH) (Uncertain)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
유해성 정보
Regulatory InformationDEA schedule II controlled substance
안전 데이터
- DEA Controlled Substances
- CSCN: 9715CSA SCH: Schedule IINARC: Yes
화학 및 산업
약리 정보
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.
용도 및 제조
Use ClassificationPharmaceuticals
응용 분야
용도Phenazocine is an opioid analgesic drug related to Pentazocine (P274300) and has a similar profile of effects. The use of Phenazocine results in analgesia and euphoria and in some cases dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors. Phenazocine is a much more potent analgesic than morphine with about 4 times the potency and very little side effects making it a better treatment option for biliary or pancreatic pain. Controlled Substance.
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