기본 정보
- 표준 SMILES
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1.Cl.Cl- InChIKey
JINNGBXKBDUGQT-UHFFFAOYSA-N- 분자식
- C35H40Cl2N4O6
- 평균 분자량
- 683.6 g/mol
- 단동위원소 질량
- 682.23249036
개요
Manidipine dihydrochloride is a diarylmethane.
이름 및 식별자
- 우선 이름
- Manidipine dihydrochloride
- IUPAC
- 5-O-[2-(4-benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;dihydrochloride
이름 및 동의어
Manidipine dihydrochloride89226-75-5manidipine hydrochlorideCalslotManidipine HClDTXSID9020796ZL507UZ6QLCV4093DTXCID30796RefChem:1556593-(2-(4-(Diphenylmethyl)piperazin-1-yl)ethyl) 5-methy (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochlorideManidipine 2HCl
이름 더 보기
CV-4093Franidipine hydrochloride3-(2-(4-Benzhydrylpiperazin-1-yl)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochlorideManidipine.2HCl126229-12-7Manidipine (dihydrochloride)MFCD00896434CV 4093
데이터베이스 식별자
- CAS
89226-75-5- PubChem CID
- 150762
- DTXSID
DTXSID9020796- ChEMBL
CHEMBL2362693- ChEBI
CHEBI:31800- UNII
- ZL507UZ6QL
- EC Number
- 680-304-3
물성
구조 계산 물성
- 극성 표면적
- 117 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 9
- 회전 가능 결합 수
- 11
- 무거운 원자 수
- 47
- 형식 전하
- 0
- 복잡도
- 1,090
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 16.7% (1 of 6) of reports.
Danger
H301+H311+H331 (16.7%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
P203, P260, P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P304+P340, P316, P318, P319, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 6 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 3 (83.3%)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
관련 반응
2건
연결된 노트
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