기본 정보
- CAS
1685-91-2- 표준 SMILES
COC1=C(C2=C(OC)C(=O)c3cc4c(c(O)c3C2=O)C(=O)OC(C)C4)C(=O)c2c(cc3c(c2O)C(=O)OC(C)C3)C1=O- InChIKey
WICHONPZVIYWIJ-UHFFFAOYSA-N- 분자식
- C30H22O12
- 평균 분자량
- 574.5 g/mol
- 단동위원소 질량
- 574.11112613
개요
Xanthomegnin is a mutagenic mycotoxin isolated from Penicillium citreo-viride. It is known to cause nephropathy and death in farm animals exposed to food-borne Penicillium (and Aspergillus fungi). In humans and animals, oral intake of xanthomegnin leads to kidney and liver abnormalities, often first presenting as jaundice. Death may result. The compound has been shown to interfere with cellular respiratory processes and has given positive results in tests for genotoxic potential.
이름 및 식별자
- 우선 이름
- 10,10'-Dihydroxy-7,7'-dimethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-(8,8'-binaphtho(2,3-c)pyran)-1,1',6,6',9,9'-hexone
- IUPAC
- 10-hydroxy-8-(10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3,4-dihydrobenzo[g]isochromen-8-yl)-7-methoxy-3-methyl-3,4-dihydrobenzo[g]isochromene-1,6,9-trione
- 현지명
- 잔토메그닌
- 영어명
- xanthomegnin
- 분자식
- C30H22O12
- 분자량
- 574.49
이름 및 동의어
DTXSID6093750010,10'-Dihydroxy-7,7'-dimethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-(8,8'-binaphtho(2,3-c)pyran)-1,1',6,6',9,9'-hexone10,10'-Dihydroxy-7,7'-dimethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-[8,8'-binaphtho[2,3-c]pyran]-1,1',6,6',9,9'-hexoneRefChem:1057176DTXCID60136606310-hydroxy-8-(10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3,4-dihydrobenzo[g]isochromen-8-yl)-7-methoxy-3-methyl-3,4-dihydrobenzo[g]isochromene-1,6,9-trioneNSC264720C30H22O12MFCD00902622NS001263153,3'-bis(2-methoxy-5-hydroxy-7-(2-hydroxypropyl)-8- carboxyl-1,4-naphthoquinone lactone)[8,2-c]pyran]-1,1',7,7',10,10'-hexone, 3,3',4,4'-tetrahydro-6,6'-dihydroxy-9,9'-dimethoxy-3,3'-dimethyl-, (3R,3'R)-
이름 더 보기
잔토메그닌NSC 264720xanthomegninXanthomegnineModafinil Impurity 16Xanthomegnin, iNOS inhibitor(3R,3'R)-3,3'-Dimethyl-7,7'-dimethoxy-10,10'-dihydroxy-3,3',4,4'-tetrahydro-8,8'-bi[1H-naphtho[2,3-c]pyran]-1,1',6,6',9,9'-hexone
물성
구조 계산 물성
- XLogP
- 4
- 극성 표면적
- 180 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 12
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 42
- 형식 전하
- 0
- 복잡도
- 1,260
물리화학적 성질
- 끓는 점
- 943.7 · 943.7±65.0 °C(Predicted)
- 밀도
- 1.63 · 1.63±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 5.61 · 5.61±0.40(Predicted)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
독성 정보
Exposure RoutesOral, dermal, inhalation, and parenteral (contaminated drugs). (A3101)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
화학 및 산업
용도 및 제조
UsesXanthomegnin is a mutagenic mycotoxin isolated from Penicillium citreo-viride.
응용 분야
용도Xanthomegnin is a napthoquinone mycotoxin and its presence in the epidermis is used in the diagnosis of a Trichophyton rubrum infections.
공급사9 곳
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Aladdin Scientific[email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
西安莱茵生物科技有限公司86-(0)29-85992781 17792393971 · [email protected]
Novachemistry44-20819178-90 02081917890 · [email protected]
上海同田生物技术有限公司021-51320588 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
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