기본 정보
- CAS
1808-12-4- 표준 SMILES
C[NH+](C)CCOC(c1ccccc1)c1ccc(Br)cc1.[Cl-]- InChIKey
ZQDJSWUEGOYDGT-UHFFFAOYSA-N- 분자식
- C17H21BrClNO
- 평균 분자량
- 370.7 g/mol
- 단동위원소 질량
- 369.0495
개요
Bromazine hydrochloride is the hydrochloride salt of bromazine. An antihistamine with antimicrobial properties, it is used in the control of cutaneous allergies. It has a role as an antimicrobial agent, a H1-receptor antagonist, a histamine antagonist and a muscarinic antagonist. It is a hydrochloride and an organobromine compound.
이름 및 식별자
- 우선 이름
- bromazine HCl
- IUPAC
- 2-[(4-bromophenyl)-phenylmethoxy]ethyl-dimethylazanium chloride
- 현지명
- 브로모디펜히드라민염화물(200MG)
- 영어명
- Bromazine Hydrochloride
- 분자식
- C17H21BrClNO
- 분자량
- 370.71174
이름 및 동의어
bromazine HCl2-[(4-bromophenyl)-phenylmethoxy]ethyl-dimethylazanium;chlorideBromanyl (TN)orb1305367Diphenhydramine Impurity C hydrochlorideNS00082892D03166T251802-(p-bromo-alpha-phenylbenzyloxy)-N,N-dimethylethylamine hydrochloride2-[(4-bromophenyl)(phenyl)methoxy]-N,N-dimethylethanaminium chloride2-[(4-bromophenyl)(phenyl)methoxy]-N,N-dimethylethanamine hydrochloride (1:1)브로모디펜히드라민염화물(200MG)
이름 더 보기
deserolbromazinCetirizine-dbromo-benzdrylEINECS 204-238-8ambodrylhydrochloridebromazine hydrochlorideBromodiphenhydramine HClDIPHENHYDRAMINE EP IMP C
데이터베이스 식별자
- CAS
물성
구조 계산 물성
- 극성 표면적
- 13.7 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 21
- 형식 전하
- 0
- 복잡도
- 258
물리화학적 성질
- 녹는점
- 144 · 144-145°
- 저장 조건
- Refrigerator
- 용해도
- 아세톤(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 고체
- 색상
- 옅은 노랑
- BRN
- 3754363 · 3754363
- 주요 응용
- 의약품(소분자)
- InChI
- InChI=1S/C17H20BrNO.ClH/c1-19(2)12-13-20-17(14-6-4-3-5-7-14)15-8-10-16(18)11-9-15;/h3-11,17H,12-13H2,1-2H3;1H
- InChIKey
- ZQDJSWUEGOYDGT-UHFFFAOYSA-N
- SMILES
- C(OCCN(C)C)(C1=CC=CC=C1)C1=CC=C(Br)C=C1.Cl
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- WGK 1
- HS 번호
- 2922190900
- Hazard Classifications
- Acute Tox. 4 Oral
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
개요Bromodiphenhydramine is a histamine H1 receptor antagonist. It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 μg/ml. Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats. It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg.
용도Antihistaminic.
일반 설명Bromodiphenhydraminehydrochloride, 2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine hydrochloride(Ambodryl Hydrochloride), is a white to pale buff crystallinepowder that is freely soluble in water and in alcohol.Relative to diphenhydramine, bromodiphenhydramine ismore lipid soluble and was twice as effective in protectingagainst the lethal effects of histamine aerosols.
공급사67 곳
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北京华美互利生物化工010-56205725 · [email protected]
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武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
怀化元研达生物技术有限责任公司18711085600 · [email protected]
山东艾莎科技有限公司15092135101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
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