CAS 547-32-0 Sulfadiazine Sodium (HCID 15899898)

기본 정보

CAS: 547-32-0
표준 SMILES: Nc1ccc(S(=O)(=O)[N-]c2ncccn2)cc1.[Na+]
InChIKey: JLDCNMJPBBKAHH-UHFFFAOYSA-N
분자식: C10H9N4NaO2S
평균 분자량: 272.26 g/mol
단동위원소 질량: 272.03439081

개요

Sulfadiazine Sodium is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

이름 및 식별자

우선 이름: Sulfadiazine Sodium
IUPAC: sodium (4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
현지명: 설파다이아진소듐
영어명: Sodium sulfadiazine
분자식: C10H11N4NaO2S
분자량: 274.27

이름 및 동의어

SULFADIAZINE SODIUMSodium sulfadiazine547-32-0SoludiazineSuthogenSodium sulfapyrimidineSulfadiazina sodicaSoluble sulfadiazineMonosodium 2-sulfanilamidopyrimidine2-Sulfanilamidopyrimidine sodium saltEINECS 208-919-0NSC 117870

이름 더 보기

설파다이아진소듐SULFADIAZINE SODIUM SALTsolublesulfadiazineSODIUMSULPHADIAZINESPS AGAR SUPPLEMENTSulfadiazin-natriumSULFADIAZINE SODIUNSULFADIAZINE SODIDUMsodiumsulfapyrimidine

UNII-84CS1P306FN(sup 1)-2-Pyrimidinylsulfanilamide monosodium salt84CS1P306FSulfadiazina sodica [INN-Spanish]Sulfadiazine sodique [INN-French]Sulfadiazinum natricum [INN-Latin]NSC117870Sodium, (N(sup 1)-2-pyrimidinylsulfanilamido)-

데이터베이스 식별자

CAS: 547-32-0
PubChem CID: 15899898
DTXSID: DTXSID20203152

물성

구조 계산 물성

극성 표면적: 95.3 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 6
회전 가능 결합 수: 3
무거운 원자 수: 18
형식 전하: 0
복잡도: 332

실험 및 물리화학적 성질

Human Drugs · 2건

FDA approved drugs -> Active ingredient

Animal DrugsActive Ingredients (Sulfadiazine Sodium) -> FDA Greenbook

물리화학적 성질

녹는점: 300 °C · >300°C
저장 조건: 2 · Keep in dark place,Inert atmosphere,2-8°C
용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태: Solid
색상: 흰색에서 황백색까지
BRN: 4068213 · 4068213
안정성: 흡습성
주요 응용: 법의학 및 독성학의약품(소분자)
InChI: InChI=1S/C10H10N4O2S.Na.H/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;;/h1-7H,11H2,(H,12,13,14);;
InChIKey: JLDCNMJPBBKAHH-UHFFFAOYSA-N
SMILES: S(C1C=CC(N)=CC=1)(=O)(=O)NC1=NC=CC=N1.[NaH]

화학적 성질

White to yellow crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 2% (1 of 49) of reports.

Danger

H302 (93.9%): Harmful if swallowed [Warning Acute toxicity, oral]

P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Other Safety InformationIMAP assessments - Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosodium salt: Human health tier I assessment

Hazard Classes and CategoriesAcute Tox. 4 (93.9%)

안전 데이터

wgk: 3
rtecs: WP2000000
ridadr: 3249
risk_code: 22-36/37/38-42/43
hazard_code: Xn
safety_code: 22-26-36/37-45
포장분류: III
위험 등급: 6.1(b)
F 고인화성물질: 10-21
Hazard Classifications: Acute Tox. 4 OralAquatic Chronic 2Eye Irrit. 2Skin Irrit. 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

응용 분야 · 2건

용도Sulfadiazine Sodium Salt can be used as reactant/reagent in preparation and crystal structure of aminophenyl sulfonamide tetrahalides, hydrochloride and hydrobromide cocrystals with iodine.

일반 설명Soluble sulfadiazine is an anhydrous, white, colorless, crystallinepowder soluble in water (1:2) and slightly soluble inalcohol. Its water solutions are alkaline (pH 9–10) and absorbcarbon dioxide from the air, with precipitation of sulfadiazine.It is administered as a 5% solution in sterile waterintravenously for patients requiring an immediately highblood level of the sulfonamide.

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

湖北金梭生物科技有限公司00123456789 · [email protected]

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