(2R,3aR,6aR)-라미프릴

(2R,3aR,6aR)-1-((2S)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid

HCID 15923014
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기본 정보

CAS
129939-63-5
표준 SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@@H](C(=O)O)C[C@H]2CCC[C@H]21
InChIKey
HDACQVRGBOVJII-ABHMUUKNSA-N
분자식
C23H32N2O5
평균 분자량
416.5 g/mol
단동위원소 질량
416.23112213

이름 및 식별자

우선 이름
(2R,3aR,6aR)-1-((2S)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
IUPAC
(2R,3aR,6aR)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
현지명
(2R,3aR,6aR)-라미프릴
영어명
(2R,3aR,6aR)-Ramipril
분자식
C23H32N2O5
분자량
416.51

이름 및 동의어

129939-63-5Ramipril EP Impurity N(2R,3aR,6aR)-RamiprilRamipril impurity N [EP]Ramipril isomer, (S,S,R,R,R)-MFY4AI76OW(2R,3aR,6aR)-1-((2S)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid(2R,3aR,6aR)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid(+)-Cyclopenta(b)pyrrole-2-carboxylic acid, 1-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2R,3aR,6aR)-(2R,3aR,6aR)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acidCyclopenta(b)pyrrole-2-carboxylic acid, 1-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2R,3aR,6aR)-UNII-MFY4AI76OW
이름 더 보기
(2R,3aR,6aR)-라미프릴(2R,3αR,6αR)-RamiprilRemipril EP Impurity NRaMipril IMpurity-N(EP)Ramipril EP Impurity N HClRamipril Impurity 14(Ramipril EP Impurity N)Ramipril EP Impurity N (Ramipril (S,S-R,R,R)-Isomer)(2R,3aR,6aR)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta [b] pyrrole-2-carboxylic acid(2R,3aR,6aR)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic Acid
C23H32N2O5(2R,3aR,6aR)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic Acid; [2R-[1[S*(S*)],2alpha,3abeta,6abeta]]-1-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic Acid; Ramipril EP Impurity N;(2R,3?R,6?R)-Ramiprilorb3215609SCHEMBL3533199FR27675RAMIPRIL IMPURITY N [EP IMPURITY]Q27284008

데이터베이스 식별자

CAS
129939-63-5
PubChem CID
15923014
UNII
MFY4AI76OW
Nikkaji
J1.380.336F

물성

구조 계산 물성

XLogP
1.4
극성 표면적
95.9 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
6
회전 가능 결합 수
10
무거운 원자 수
30

물리화학적 성질

녹는점
40 · 40 - 50°C
끓는 점
616.166 · 616.166±55.00 °C(Press: 760.00 Torr)(predicted)
밀도
1.201 · 1.201±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
저장 조건
-20 °C · -20°C Freezer, Under inert atmosphere
용해도
아세토니트릴(약간), 메탄올(약간)에 용해됨
산도 계수 (pKa)
3.148 · 3.148±0.20(predicted)

화학 및 산업

응용 분야

용도(2R,3aR,6aR)-Ramipril (Ramipril EP Impurity N) is an isomer of the angiotensin-converting enzyme (ACE) inhibitor Ramipril (R111000). Ramipril impurity N.

상·하류 제품 정보

공급사26 곳

天津始加生物医药科技有限公司15022261580 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]

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