데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다
기본 정보
- CAS
405911-17-3- 표준 SMILES
Cl.O=C(O)Cc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1- InChIKey
NMPUWJFHNOUNQU-UHFFFAOYSA-N- 분자식
- C33H32Cl2F3NO3
- 평균 분자량
- 618.5 g/mol
- 단동위원소 질량
- 617.1711339
개요
GW3965 hydrochloride is an organic molecular entity. It has a role as a liver X receptor agonist.
이름 및 식별자
- 우선 이름
- GW3965 hydrochloride
- IUPAC
- 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid;hydrochloride
- 현지명
- GW3965염산염
- 영어명
- GW 3965 hydrochloride
- 분자식
- C33H31ClF3NO3.HCl
- 분자량
- 0
이름 및 동의어
GW3965 hydrochlorideRefChem:783288637-023-6405911-17-3GW3965 HClGW 3965 HYDROCHLORIDE2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochlorideGW3965 (hydrochloride)2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid;hydrochlorideMFCD082769202-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid hydrochloride
이름 더 보기
GW3965염산염CS-742GW3965 HCl SaltGW3965 HCl ，S2630W 3965 HYDROCHLORIDEGW3965 hydrochloride, >=98%GW-3965 hydrochloride GW3965GW 3965 hydrochloride, LXR agonistGW3965 hydrochloride, 10 mM in DMSO
3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid HydrochlorideC33H32Cl2F3NO3405911-17-3 (HCl)2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy)-phenyl)acetic acid hydrochloride salt2-(3-{3-[[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy}-phenyl)acetic acid hydrochloride saltGW-3965 hydrochlorideGW-3965 hydrochloride?MLS006011227
물성
구조 계산 물성보충 중
- 극성 표면적
- 49.8 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 13
- 무거운 원자 수
- 42
- 형식 전하
- 0
- 복잡도
- 753
물리화학적 성질
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 20 mg/mL · DMSO: ≥20mg/mL
- 물리적 상태
- 가루
- 색상
- 하얀색
- InChIKey
- NMPUWJFHNOUNQU-UHFFFAOYSA-N
- SMILES
- Cl[H].OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c3ccccc3)Cc4cccc(c4Cl)C(F)(F)F)c1
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P273, P280, P301+P317, P305+P354+P338, P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 4 (100%)
안전 데이터
- wgk
- 3
- risk_code
- 22-41
- hazard_code
- Xn
- safety_code
- 26-39
- Hazard Classifications
- Acute Tox. 4 OralAquatic Chronic 4Eye Dam. 1
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
용도GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
공급사100 곳
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]
泰州葛林美克医药科技有限公司15366892466 · [email protected]
武汉布林科技有限公司3456065315 13260619011 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海冬洋生物科技有限公司0512-13601744364 13601744364 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
관련 반응
3건
화합물 노트
불러오는 중…