알에이치-올리고펩타이드-1
Nepidermin
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기본 정보
- CAS
62253-63-8- 표준 SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O- InChIKey
GVUGOAYIVIDWIO-UFWWTJHBSA-N- 분자식
- C270H401N73O83S7
- 평균 분자량
- 6,222.075 g/mol
- 단동위원소 질량
- 6,217.74465029
이름 및 식별자
- 우선 이름
- Nepidermin
- 현지명
- 알에이치-올리고펩타이드-1
- 영어명
- Epidermal Growth Factor
- 분자식
- C270H401N73O83S7
- 분자량
- 6221.96724
이름 및 동의어
알에이치-올리고펩타이드-1에스에이치-올리고펩타이드-1표피성장인자EGFsh-Oligopeptide-1HEGFRHEGFHUMAN EGFNepiderMinrh-Oligopeptide-1HUMAN EPIDERMAL GROWTH FACTOREPIDERMAL GROWTH FACTOR (EGF) HUMAN
이름 더 보기
EGP
데이터베이스 식별자
- CAS
62253-63-8- PubChem CID
- 16143379
- DTXSID
DTXSID80211314- EC Number
- 810-845-4
물성
물리화학적 성질
- 저장 조건
- -20 °C · -20°C
- 용해도
- 0.19 · water: soluble 0.190-0.210, clear, colorless
- 물리적 상태
- 가루
- 색상
- 하얀색
- 생물학적 소스
- rabbit
- 수용성
- water: soluble, clear, colorless
- 화장품 원료 기능
- 피부 컨디셔닝피부 보호
- InChIKey
- GVUGOAYIVIDWIO-UFWWTJHBSA-N
화학적 성질
Endotoxin
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- rtecs
- KB4518000
- HS 번호
- 2937190000
- F 고인화성물질
- 10-21
- 스토리지 클래스
- 13 - Non Combustible Solids
화학 및 산업
응용 분야
개요An ophthalmic formulation of epidermal growth factor (urogastrone) has been launched for stimulation of healing of the corneal epithelium following various corneal diseases.
용도Epidermal Growth Factor, human, animal component free has been used: as a supplement in in LHC-8 medium to culture liver cell lines in the fetal bovine serum (FBS)-Dulbecco′s modified essential medium (DMEM) /F12 medium for primary culture of human glioma cells as an additive in the conditional medium of normal fibroblasts (NFs) to study its effect on the migration and invasion of endometrial cancer (EC) cellsas a component in tumorsphere medium
일반 설명Epidermal Growth Factor (EGF) is a small mitogenic polypeptide (～6 kDa), which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family, which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is homologous to a sequence contained in a 19 kDa protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cell EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
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