데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다
기본 정보
- CAS
60756-83-4- 표준 SMILES
OC1CCC(c2ccccc2)(N2CCCCC2)CC1- InChIKey
KPRUAZBLIREHPD-UHFFFAOYSA-N- 분자식
- C17H25NO
- 평균 분자량
- 259.393 g/mol
- 단동위원소 질량
- 259.19361442
이름 및 식별자
- 우선 이름
- 4-Phenyl-4-piperidinocyclohexanol
- IUPAC
- 4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol
- 현지명
- (트랜스)-4-PPC
- 영어명
- (trans)-4-PPC
- 분자식
- C17H25NO
- 분자량
- 259.39
이름 및 동의어
(트랜스)-4-PPC(trans)-4-PPCKPRUAZBLIREHPD-QAQDUYKDSA-Nac trans-4’-Hydroxy Phencyclidinerac trans-4'-Hydroxy Phencyclidinetrans-4-Phenyl-4-piperidinocyclohexanol4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol2H5]-trans-4-Phenyl-4-piperidinocyclohexanoltrans-4-Phenyl-4-(1-piperidinyl)cyclohexanoltrans-1-(1-Phenyl-4-hydroxycyclohexyl)piperidinerac trans-4-Phenyl-4-(1-piperidinyl)cyclohexanol
데이터베이스 식별자
- CAS
60756-83-4、78165-06-7、78165-07-8- PubChem CID
- 162171
- DTXSID
DTXSID60209577- ChEMBL
CHEMBL266562、CHEMBL273446- ChEBI
CHEBI:183505- UNII
- TAJ3PEY6RN
- Nikkaji
- J1.002.574E、J390.379F、J438.408C
물성
물리화학적 성질
- 끓는 점
- 382.5 · 382.5±42.0 °C(Predicted)
- 밀도
- 1.093 · 1.093±0.06 g/cm3(Predicted)
- 용해도
- 5 mg/ml; · DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 15.1 · 15.10±0.40(Predicted)
화학 및 산업
응용 분야
개요trans-4-phenyl-4-Piperidinocyclohexanol (Item No. 20565) is an analytical reference standard that is structurally categorized as an arylcyclohexylamine. It is a metabolite of phencyclidine (PCP; ). trans-4-phenyl-4-Piperidinocyclohexanol inhibits dopamine uptake in rat striatal synaptosomes to a similar extent as PCP. This product is intended for research and forensic applications.
용도trans-4-Phenyl-4-(1-piperidinyl)cyclohexanol [(trans)-4-PPC] is the trans-isomer of the 4-hydroxy(cyclo) metabolite of Phencyclidine (P295502). Studies show that (trans)-4-PPC elicits dose-related increases in locomotor activity and rearing in mice, and (trans)-4-PPC may also be involved in psychotomimetic effects of PCP due to its inhibitory effect on DA uptake.
관련 반응
3건
화합물 노트
불러오는 중…