기본 정보
- CAS
2210-63-1- 표준 SMILES
CCCCC1C(=O)NN(c2ccccc2)C1=O- InChIKey
REOJLIXKJWXUGB-UHFFFAOYSA-N- 분자식
- C13H16N2O2
- 평균 분자량
- 232.28 g/mol
- 단동위원소 질량
- 232.12117776
개요
Mofebutazone is a pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain. It has a role as a non-steroidal anti-inflammatory drug and a non-narcotic analgesic.
이름 및 식별자
- 우선 이름
- Mofebutazone
- IUPAC
- 4-butyl-1-phenylpyrazolidine-3,5-dione
- 현지명
- 모페부타존
- 영어명
- MOFEBUTAZONE
- 분자식
- C13H16N2O2
- 분자량
- 232.28
이름 및 동의어
Mofebutazone2210-63-14-butyl-1-phenylpyrazolidine-3,5-dioneMonophenylbutazoneMophebutazone2 FdbpMofebutazonaMofebutazonumMonazone4-Butyl-1-phenyl-3,5-pyrazolidinedione4-Butyl-1-phenyl-3,5-dioxopyrazolidineSPW36WUI5Z
이름 더 보기
모페부타존monobutyl2fdbpmonazanmobuzonreumatoxmobutazonmonorheumettenarcomonoltablets
2-Phenyl-3,5-dihydroxy-4-butylpyrazolidineNSC-73725DTXSID4023331CHEBI:762521-phenyl-4-n-butyl-3,5-dioxopyrazolidineRefChem:159305DTXCID203331M01AA02
데이터베이스 식별자
- CAS
2210-63-1- PubChem CID
- 16639
- DTXSID
DTXSID4023331- ChEMBL
CHEMBL1892201- ChEBI
CHEBI:76252- UNII
- SPW36WUI5Z
- EC Number
- 218-641-1
- Nikkaji
- J7.362H
물성
구조 계산 물성
- XLogP
- 2.7
- 극성 표면적
- 49.4 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 17
- 형식 전하
- 0
- 복잡도
- 298
물리화학적 성질
- 녹는점
- 102 · 102-103°
- 끓는 점
- 374.44 °C · 374.44°C (rough estimate)
- 밀도
- 1.1099 · 1.1099 (rough estimate)
- 굴절률
- 1.645 · 1.6450 (estimate)
- 저장 조건
- Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 5.22 · 5.22±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 1 notifications to the ECHA C&L Inventory.
유해성 정보
Other Safety InformationIMAP assessments - 3,5-Pyrazolidinedione, 4-butyl-1-phenyl-: Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (100%)
안전 데이터
- 독성
- LD50 i.v. in mice: 600 mg/kg (Schoetensack)
화학 및 산업
약리 정보
ATC Code
M - Musculo-skeletal system
M - Musculo-skeletal system
QM - Musculo-skeletal system
QM - Musculo-skeletal system
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
응용 분야
용도Mofebutazone is an anti-inflammatory drug used on the gastrointestinal and renal tissues.
상·하류 제품 정보
상류 원료
공급사33 곳
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉鹏垒生物科技有限公司15871464247 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
佛山宝诺生物科技有限公司0757-85921206 18520245316 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
PT CHEM GROUP LIMITED+86-85511178; +86-85511178 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
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上海前衍生物科技有限公司02781293128 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
山东西亚化学有限公司4009903999 13395398332 · [email protected]
成都华纯科技有限公司400-1166-196 15982826727 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
上海百舜生物科技有限公司021-37581181 · [email protected]
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Aladdin Scientific[email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
武汉鹏垒生物科技有限公司15871464247 17307245989 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
广州市震霖医药科技有限公司020-18102736 13622807357 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
广州奥司汀生物技术有限公司15918640830 13268843209 · [email protected]
추가 설명
정의ChEBI: A pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain.
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