기본 정보
- CAS
125251-66-3- 표준 SMILES
Cl.Oc1ccc(CCCCNC[C@H](O)c2ccc(O)c(O)c2)cc1- InChIKey
ATBUNPBAFFCFKY-FERBBOLQSA-N- 분자식
- C18H24ClNO4
- 평균 분자량
- 353.8 g/mol
- 단동위원소 질량
- 353.1393859
개요
Arbutamine Hydrochloride is the hydrochloride salt form of arbutamine, a synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease.
이름 및 식별자
- 우선 이름
- Arbutamine Hydrochloride
- IUPAC
- 4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
- 영어명
- Arbutamine Hydrochloride
- 분자식
- C18H24ClNO4
- 분자량
- 353.84
이름 및 동의어
Arbutamine hydrochlorideGenesaArbutamine HCl125251-66-3K0NF2CPJ7FGP-2-121-3DTXSID40154718RefChem:56704DTXCID2077209Arbutamine hydrochloride [USAN]ARBUTAMINE (Hydrochloride)4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
이름 더 보기
1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-, hydrochloride (1:1) (ACI)
Arbutamine hydrochloride (USAN)UNII-K0NF2CPJ7FGenesa (TN)(R)-3,4-Dihydroxy-alpha-(((4-(p-hydroxyphenyl)butyl)amino)methyl)benzyl alcohol hydrochlorideSCHEMBL40757orb1698351CHEMBL1200385ARBUTAMINE HYDROCHLORIDE [MI]
데이터베이스 식별자
- CAS
125251-66-3- PubChem CID
- 166551
- DTXSID
DTXSID40154718- ChEMBL
CHEMBL1200385- UNII
- K0NF2CPJ7F
물성
구조 계산 물성
- 극성 표면적
- 93 Ų
- 수소 결합 공여자 수
- 6
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 8
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 320
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
물리화학적 성질
- 녹는점
- 55 · 55-58°
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that selectively bind to and activate beta-adrenergic receptors.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
상·하류 제품 정보
상류 원료
공급사6 곳
Chongqing jooe co., ltd+86-15223382610 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
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