palladium(II) acetate

HCID 167845CAS 19807-27-3

기본 정보

표준 SMILES: CC(=O)[O-].CC(=O)[O-].[Pd+2]
InChIKey: YJVFFLUZDVXJQI-UHFFFAOYSA-L
분자식: C4H6O4Pd
평균 분자량: 224.51 g/mol
단동위원소 질량: 223.93009467

개요

Palladium acetate is a chemical compound of palladium. It is used as a catalyst for many organic reactions and as a precursor to other palladium(II) compounds. Palladium is a chemical element with the chemical symbol Pd and an atomic number of 46. It is found as a free metal alloyed with gold and other platinum group metals and in the rare minerals cooperite and polarite. (L794, L804)

이름 및 식별자

우선 이름: palladium(II) acetate
IUPAC: palladium(2+) diacetate

이름 및 동의어

Palladium(II) acetate3375-31-3Palladium diacetateDiacetatopalladiumDiacetoxypalladiumBis(acetato)palladiumBisacetylpalladiumPalladous acetatePalladium(2+) acetatePd(OAc)2Acetic acid palladium saltAcetic acid, palladium salt

이름 더 보기

0LTG3460Y5DTXSID10890575(ACETYLOXY)PALLADIO ACETATERefChem:169636DTXCID601030789222-164-4243-333-9Palladium acetate

데이터베이스 식별자

CAS: 19807-27-3、3375-31-3
PubChem CID: 167845
DTXSID: DTXSID10890575
UNII: 0LTG3460Y5
EC Number: 222-164-4、243-333-9
Nikkaji: J10.642I

물성

구조 계산 물성

극성 표면적: 80.3 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 25.5

실험 및 물리화학적 성질

Chemical ClassesMetals -> Organic Acids, Metal Salts

Physical DescriptionReddish-brown solid; Insoluble in water; [Hawley] Powder; [MSDSonline]

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H302 (11.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 265 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: Acetic acid, palladium(2+) salt

Status: Active Update: 21-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17957

Palladium (II) acetate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Acetic acid, palladium(2+) salt: Environment tier I assessment

Hazards SummaryCorrosive to eyes; [eChemPortal: ERMA] An irritant; May cause serious injury to eyes; [MSDSonline]

Hazard Classes and CategoriesAcute Tox. 4 (11.3%)

독성 정보

Health EffectsContact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)

Toxicity Summary · 1건

Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)

Signs and SymptomsSkin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)