기본 정보
- CAS
198774-27-5- 표준 SMILES
C#CC[C@H](N)C(=O)O- InChIKey
DGYHPLMPMRKMPD-BYPYZUCNSA-N- 분자식
- C5H7NO2
- 평균 분자량
- 113.11 g/mol
- 단동위원소 질량
- 113.04767846
개요
L-propargylglycine is a non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens has been replaced by an ethynyl group. It causes the irreversible inactivation of gamma-cystathionase (also known as cystathionine gamma-lyase) and is used as an affinity labeling reagent for gamma-cystathionase and other enzymes. It has a role as an EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor, an EC 1.4.3.2 (L-amino-acid oxidase) inhibitor and an EC 2.6.1.2 (alanine transaminase) inhibitor. It is a terminal acetylenic compound and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a L-propargylglycine zwitterion.
이름 및 식별자
- 우선 이름
- L-Propargylglycine
- IUPAC
- (2S)-2-aminopent-4-ynoic acid
- 영어명
- L-Propargylglycine HCL
- 분자식
- C5H7NO2.ClH
- 분자량
- 149.58
이름 및 동의어
L-PROPARGYLGLYCINE23235-01-0(2s)-2-aminopent-4-ynoic acid(S)-2-PropargylglycineL-2-Propynylglycine(S)-2-Amino-4-pentynoic acidL-C-Propargylglycine4-Pentynoic acid, 2-amino-, (2S)-(S)-Propargylglycine(S)-alpha.Propargylglycine(S)-alpha-propargylglycine8R9U8RVT6V
이름 더 보기
D-PropargylglycineH-GLY(PROPARGYL)-OHH-PROPARGYL-GLYCINEH-PRA-OHH-PROPARGYL-GLY-OHL-PROPARGYL-GLY-OHN-PropargylglycineRARECHEM BK PT 0255
CHEBI:437974-Pentynoic acid, 2-amino-, (S)-PROPARGYLGLYCINE, L-(2S)-2-azaniumylpent-4-ynoateRefChem:797390812-854-9(S)-2-Aminopent-4-ynoic acid(2S)-2-amino-4-Pentynoic acid
데이터베이스 식별자
- CAS
198774-27-5、23235-01-0- PubChem CID
- 168091
- DTXSID
DTXSID60941728- ChEMBL
CHEMBL50483
물성
구조 계산 물성
- XLogP
- -2.8
- 극성 표면적
- 63.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 2
- 무거운 원자 수
- 8
- 형식 전하
- 0
- 복잡도
- 133
물리화학적 성질
- 녹는점
- 265 · 265-266 °C
- 저장 조건
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- 물리적 상태
- solid
- InChI
- InChI=1/C5H7NO2.ClH/c1-2-3-4(6)5(7)8;/h1,4H,3,6H2,(H,7,8);1H/t4-;/s3
- InChIKey
- UAMBUICGODABQY-NDILARRWNA-N
- SMILES
- [C@@H](N)(C(=O)O)CC#C.Cl |&1:0,r|
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
안전 데이터
- wgk
- 3
- safety_code
- 22-24/25
- F 고인화성물질
- 10
화학 및 산업
공급사100 곳
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
江苏生康迈翔科技有限公司18217475093 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
郑州鸿晟医药科技有限公司0371-55695890 15637198702 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
苏州新瑞生物科技有限公司13401437572 · [email protected]
嘉兴市艾森化工有限公司0573-85285100 18627885956 · [email protected]
VDM Biochemicals0330-2528181 · [email protected]
관련 반응
1건
화합물 노트
불러오는 중…