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기본 정보
- CAS
28115-68-6- 표준 SMILES
COc1cc(C[C@H]2C(=O)OC[C@@H]2Cc2ccc3c(c2)OCO3)ccc1O- InChIKey
OCTZTNYFALPGHW-LSDHHAIUSA-N- 분자식
- C20H20O6
- 평균 분자량
- 356.374 g/mol
- 단동위원소 질량
- 356.12598836
이름 및 식별자
- 우선 이름
- 4-[(2H-1,3-Benzodioxol-5-yl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
- IUPAC
- (3R,4R)-4-[(2H-1,3-Benzodioxol-5-yl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
- 현지명
- 플루비아톨리드
- 영어명
- pluviatolide
- 분자식
- C20H20O6
- 분자량
- 356.37
이름 및 동의어
플루비아톨리드pluviatolidetrans-Pluviatolide3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-(3R,4R)-4-[(1,3-Benzodioxol-5-yl)methyl]-4,5-dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]furan-2(3H)-one
데이터베이스 식별자
- CAS
28115-68-6- PubChem CID
- 168759
- DTXSID
DTXSID00950854- ChEMBL
CHEMBL63962- ChEBI
CHEBI:90896- Nikkaji
- J17.298G
물성
물리화학적 성질
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- 물리적 상태
- 고체
- 색상
- White to off-white
- LogP
- 2.59 · 2.590 (est)
화학 및 산업
응용 분야
개요Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties. It scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in cell-free assays (IC50s = 23.2 and 88.5 μM, respectively). Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 μM. It decreases contractions induced by acetylcholine in isolated guinea pig ileum when used at concentrations of 30 and 100 μM.
공급사22 곳
成都乐美天医药科技有限公司17308096051 17308096051 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
雷丁试剂0510-85629785 18013409632 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
武汉天植生物技术有限公司18607101326 15172504745 · [email protected]
四川精萃天成药物科技有限公司028-87865381 18108190480 · [email protected]
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