기본 정보
- CAS
31059-54-8- 표준 SMILES
C[N+](C)(C)CCC(=O)c1ccc2ccccc2c1.[I-]- InChIKey
LIFHUGCXEAQKRZ-UHFFFAOYSA-M- 분자식
- C16H20INO
- 평균 분자량
- 369.24 g/mol
- 단동위원소 질량
- 369.05896226
개요
structure given in first source; RN given refers to iodide
이름 및 식별자
- 우선 이름
- 2-Naphthoylethyltrimethylammonium
- IUPAC
- trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium iodide
- 현지명
- 2-나프토일에틸트리메틸암모늄
- 영어명
- 2-naphthoylethyltrimethylammonium
- 분자식
- C16H20NO.I
- 분자량
- 369.24
이름 및 동의어
31059-54-82-NaphthoylethyltrimethylammoniumRefChem:88641beta-NETAtrimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium;iodide-NETAbeta-NETA, 98%2-(beta-Naphthoyl)ethyltrimethylammonium iodideorb1308670SCHEMBL11253161DTXSID60953164AKOS040741094
이름 더 보기
2-나프토일에틸트리메틸암모늄α-NETAβ-NETAβ-NETA, 10 mM in DMSOalpha-NETA, Fluorescent ChAT inhibitor2-Dimethylaminoethyl 2-naphthyl ketone methiodidetrimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodidehistamine,Cholinesterase (ChE),Apoptosis,ChE,β-NETA,KCl,β NETA,ChA,choline acetyltransferase,βNETA,Inhibitor,cholinesterase,inhibit
MS-25926HY-124957CS-0089727T141942-Naphthalenepropanaminium, N,N,N-trimethyl-gamma-oxo-, iodide2-Naphthalenepropanaminium, N,N,N-trimethyl-|A-oxo-, iodide (1:1)N,N,N-trimethyl-3-(naphthalen-2-yl)-3-oxopropan-1-aminium iodide2-Naphthalenepropanaminium, N,N,N-trimethyl-gamma-oxo-, iodide (1:1)
물성
구조 계산 물성
- 극성 표면적
- 17.1 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 19
- 형식 전하
- 0
- 복잡도
- 292
물리화학적 성질
- 저장 조건
- -20 °C, · Store at -20°C, protect from light, stored under nitrogen
- 용해도
- 3 mg/ml; · DMSO: 3mg/ml; Methanol: Soluble
- 물리적 상태
- 고체
- 색상
- White to off-white
화학 및 산업
응용 분야
개요Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.
용도Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.[Cayman Chemical]
공급사17 곳
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Aladdin Scientific[email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…