2,6-Dichloropyridine (HCID 16989)

이름 및 식별자

우선 이름: 2,6-Dichloropyridine
IUPAC: 2,6-dichloropyridine
현지명: 2,6-디클로로피리딘
영어명: 2,6-Dichloropyridine
분자식: C5H3Cl2N
분자량: 147.99

이름 및 동의어

2,6-DICHLOROPYRIDINE2402-78-0Pyridine, 2,6-dichloro-DTXSID2051895WM26PC2SBWNSC-76606DTXCID0030457RefChem:83196219-282-3MFCD000062442,6-Dichloro-pyridine2,6-Dichloropyridine, 98%

이름 더 보기

2,6-디클로로피리딘26DCLPYAURORA KA-64952,6-DichLoropyridineAKOS BBS-000043142,6-Dichloropyridinr2,6-dichloro-pyridinTrazodone Impurity 30

CCRIS 1727EINECS 219-282-3NSC 76606BRN 0108664NSC766062,6-dichlorpyridine2.6-dichloropyridineUNII-WM26PC2SBW

데이터베이스 식별자

CAS: 2402-78-0
PubChem CID: 16989
DTXSID: DTXSID2051895
ChEMBL: CHEMBL3561947
UNII: WM26PC2SBW
EC Number: 219-282-3
Nikkaji: J51.304K

물성

구조 계산 물성

XLogP: 2.2
극성 표면적: 12.9 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 68

실험 및 물리화학적 성질

Physical Description · 2건

Wet Solid

White crystalline solid; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: 83 · 83-86 °C (lit.)
끓는 점: 211 °C · 211 °C
밀도: 1.5159 · 1.5159 (rough estimate)
굴절률: 1.55 · 1.5500 (estimate)
인화점: 110 °C · 110°C
저장 조건: 2 · Inert atmosphere,2-8°C
용해도: 50 mg/mL, · 메탄올: 50mg/mL, 투명
물리적 상태: 결정성 분말
산도 계수 (pKa): -3.02 · -3.02±0.10(Predicted)
색상: 흰색에서 분홍색 또는 회백색
수소이온지수(pH): 6 · 6-7 (H2O, 20℃)(saturated solution)
수용성: 1 g/L · <1g/L(20℃)
BRN: 108664 · 108664
InChI: 1S/C5H3Cl2N/c6-4-2-1-3-5(7)8-4/h1-3H
InChIKey: FILKGCRCWDMBKA-UHFFFAOYSA-N
SMILES: Clc1cccc(Cl)n1
NIST: 2 · Pyridine, 2,6-dichloro-(2402-78-0)
EPA: 2 · 2,6-Dichloropyridine (2402-78-0)

화학적 성질

White to light yellow solid

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H301 (96.6%): Toxic if swallowed [Danger Acute toxicity, oral]；H315 (15.5%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (15.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 58 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryCauses somnolence and fatty liver degeneration in intraperitoneal lethal-dose studies of mice; [RTECS] An irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Pyridine.

Hazard Classes and CategoriesAcute Tox. 3 (96.6%)；Skin Irrit. 2 (15.5%)；Eye Irrit. 2A (15.5%)；STOT SE 3 (12.1%)

독성 정보

Adverse EffectsNeurotoxin - Other CNS neurotoxin；Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

규제 정보

Regulatory Information · 2건

Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: US8400000
ridadr: UN 2811 6.1/PG 2
독성: mouse,LD50,intraperitoneal,115mg/kg (115mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LIVER: FATTY LIVER DEGERATIONBEHAVIORAL: ANTIPSYCHOTIC,Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
HS 번호: 29333999
risk_code: 25-36/37/38-22-23/24/25
hazard_code: T,Xn
safety_code: 36/37/39-45-37/39-26-36
포장분류: III
위험 등급: 6.1
위험 참고 사항: Toxic
Hazard Classifications: Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2
스토리지 클래스: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

화학 및 산업

용도 및 제조

U.S. Production2023: 53,953 lb；2022: 186,928 lb；2021: 226,252 lb；2020: 232,841 lb

Industry UsesIntermediate

General Manufacturing Information · 2건

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing

Pyridine, 2,6-dichloro-: ACTIVE

응용 분야 · 2건

개요2,6-Dichloropyridine is an important intermediate that is widely used in the medicine and pesticide research field. It could be used as a starting material to synthesize the pirozadil (Pirozadil) which can be used for reducing blood-fat, and antiplatelet condensation. 2,6-dichloropyridine also can be used to synthetic musk pyridine with alternative natural musk. 2,3,5, 6-TCP produced by further chlorination of 2, 6-dichloropyridine is an important raw material for chlorpyrifos, which is widely used in the world with high efficiency, broad spectrum, and low residue.

용도2,6-Dichloropyridine is used in the preparation of triazolo and imidazo potassium channel antagonists as antiarrythmic agents.

상·하류 제품 정보

상류 원료

피리딘 2-CHLORO-6-FLUOROPYRIDINE

하류 제품

3-아미노-6-클로로피리딘-2-카르복실산 4-Amino-2,6-dichloropyridine 2-Amino-6-methoxypyridine 2,4,6-Trichloropyridine 2-Amino-6-chloro-3-nitropyridine 6-Chloropyridn-2-ol 2,6-DIETHYNYLPYRIDINE 2,6-Dichloro-1-fluoropyridinium triflate 2,6-디(1-피라졸릴)피리딘 4,6-Dichloropyrido[3,2-d]pyrimidine 2,6-디클로로-4-메톡시-피리딘 2,6-디클로로피리딘-3,4-디아민

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

山东艾利特生物科技有限公司0539-18853986-090 13053958157 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

연결된 노트

불러오는 중…

2,6-디클로로피리딘

기본 정보