2-(2-히드록시-5-메틸페닐)벤조트리아졸

Drometrizole

HCID 17113CAS 2440-22-4

기본 정보

표준 SMILES
Cc1ccc(O)c(-n2nc3ccccc3n2)c1
InChIKey
MCPKSFINULVDNX-UHFFFAOYSA-N
분자식
C13H11N3O
평균 분자량
225.25 g/mol
단동위원소 질량
225.09021198

이름 및 식별자

우선 이름
Drometrizole
IUPAC
2-(benzotriazol-2-yl)-4-methylphenol
현지명
2-(2-히드록시-5-메틸페닐)벤조트리아졸
영어명
Drometrizole
분자식
C13H11N3O
분자량
225.25

이름 및 동의어

Drometrizole2440-22-42-(2-HYDROXY-5-METHYLPHENYL)BENZOTRIAZOLE2-(2H-Benzotriazol-2-yl)-4-methylphenolDrometrizol2-(2'-Hydroxy-5'-methylphenyl)benzotriazoleDrometrizolumPhenol, 2-(2H-benzotriazol-2-yl)-4-methyl-DTXSID10274795X93W9OFZLNSC-91885DTXCID207479
이름 더 보기
2-(2'-하이드록시-5'-메틸페닐)벤조트리아암모니아2-(2'-히드록시-5'-메틸페닐)벤조트리아암모니아2-(2-히드록시-5-메틸페닐)벤조트리아졸2-(2H-벤조트라이아졸-2-일)-4-메틸페놀2-2(-하이드록시-5-메틸페닐벤조트라이아졸드로메트리졸2-(2'-하이드록시-5'-메틸페닐)벤조트리아암모니아(2-(2'-HYDROXY-5'-METHYLPHENYL)B...페놀, 2-(2H-벤조트라이아졸-2-일)-4-메틸-UV-PUV-712-(2H-1,2,3-Benzotriazol-2-yl)-4-methylphenolBenazol IIRIASORB UV-P
219-470-5RefChem:590441607-063-9Benazol P2-(2H-Benzotriazol-2-yl)-p-cresolTinuvin P2-(2H-benzo[d][1,2,3]triazol-2-yl)-4-methylphenol2-(2-Benzotriazolyl)-p-cresol

데이터베이스 식별자

CAS
2440-22-4
PubChem CID
17113
DTXSID
DTXSID1027479
ChEMBL
CHEMBL1564747
ChEBI
CHEBI:134926
UNII
5X93W9OFZL
EC Number
219-470-5、607-063-9
Nikkaji
J7.899I

물성

구조 계산 물성

XLogP
4.3
극성 표면적
50.9 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
1
무거운 원자 수
17

실험 및 물리화학적 성질

Physical DescriptionDry Powder; Other Solid; Large Crystals
Collision Cross Section155.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID1027479]

물리화학적 성질

녹는점
125.5 · 125.5-129.5 °C(lit.)
끓는 점
10 · bp10 225°
밀도
1.38 · 1.38
증기압
0 Pa · 0Pa at 20℃
굴절률
1.56 · 1.5600 (estimate)
인화점
54 °C · 54°C

화학적 성질

Light yellow powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 0.8% (7 of 885) of reports.

Warning

H317 (97.1%): May cause an allergic skin reaction [Warning Sensitization, Skin];H410 (47%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard];H413 (46%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 885 reports by companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 7 of 885 reports by companies.;There are 18 notifications provided by 878 of 885 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 4건

Chemical: Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-

Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13300

Drometrizole: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phenolic benzotriazoles: Environment tier II assessment
Hazard Classes and Categories · 2건

Skin Sens. 1 (97.1%);Aquatic Chronic 1 (47%);Aquatic Chronic 4 (46%)

Skin sensitization - Category 1B;Specific target organ toxicity - Single exposure - Category 1 (respiratory organs);Specific target organ toxicity - Repeated exposure - Category 2 (kidney);Hazardous to the aquatic environment (Long-term) - Category 1

독성 정보

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

규제 정보

Regulatory Information · 4건

Chemical: Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-

Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13300

Drometrizole: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
GO6860000
독성
LD50 oral in mouse: 6500mg/kg
HS 번호
29339900
risk_code
36/37/38-53-43

화학 및 산업

용도 및 제조

Uses · 2건

CIR ingredient: Drometrizole

Plastics -> Typical concentration range in plastic materials -> 0.0015 - 0.5%

U.S. Production2023: 100,000 - <250,000 lb;2022: 700,000 - <850,000 lb;2021: 700,000 - <850,000 lb;2020: 550,000 - <700,000 lb
Consumer UsesOther;UV stabilizer;Antioxidant
Industry UsesUV stabilizer;Antioxidant
Household ProductsInformation on 1 consumer products that contain Drometrizole in the following categories is provided:;• Home Maintenance
Use Classification · 5건

Fragrance Ingredients

Plastics -> Light stabilisers

Plastics -> Other functions -> Other stabiliser

Cosmetics -> Uv absorber

Plastics -> Polymer Type -> Polyolefin-I; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PMMA; (E)PS

응용 분야

용도Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海创欣化学有限公司021-54253545

추가 설명

정의Drometrizole is a member of triazoles.

관련 반응

52건

연결된 노트

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