기본 정보
- CAS
52430-65-6- 표준 SMILES
CC1CCC(NC(=O)NS(=O)(=O)c2ccc(CCNC(=O)N(C)c3ccccn3)cc2)CC1- InChIKey
UIXYQZIHFQKFOZ-UHFFFAOYSA-N- 분자식
- C23H31N5O4S
- 평균 분자량
- 473.6 g/mol
- 단동위원소 질량
- 473.20967566
개요
Glisamuride is a second-generation sulfonylurea with antihyperglycemic activity. Like other larger sulfonylurea compounds, glisamuride appears to exert greater binding affinity for peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity among most of the first and second-generation agents.
이름 및 식별자
- 우선 이름
- Glisamuride
- IUPAC
- 1-methyl-3-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-1-pyridin-2-ylurea
- 현지명
- N-[[(4-메틸시클로헥실)아미노]카르보닐]-4-[2-[[(메틸-2-피리딜아미노)카르보닐]아미노]에틸]벤젠술폰아미드
- 영어명
- N-[[(4-methylcyclohexyl)amino]carbonyl]-4-[2-[[(methyl-2-pyridylamino)carbonyl]amino]ethyl]benzenesulphonamide
- 분자식
- C23H31N5O4S
- 분자량
- 473.59
이름 및 동의어
Glisamuride74680-07-252430-65-6Glisamuride [INN]HB 1801-methyl-3-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-1-pyridin-2-ylurea4-(2-(3-Methyl-3-(pyridin-2-yl)ureido)ethyl)-N-((4-methylcyclohexyl)carbamoyl)benzenesulfonamideT4C1IE36L01-Methyl-3-(p-((3-(4-methylcyclohexyl)ureido)sulfonyl)phenethyl)-1-(2-pyridyl) ureaUNII-T4C1IE36L0GlisamuridaEINECS 277-965-1
이름 더 보기
N-[[(4-메틸시클로헥실)아미노]카르보닐]-4-[2-[[(메틸-2-피리딜아미노)카르보닐]아미노]에틸]벤젠술폰아미드N-[[(4-Methylcyclohexyl)amino]carbonyl]-4-[2-[[[methyl(2-pyridyl)amino]carbonyl]amino]ethyl]benzenesulfonamideN-[[(4-methylcyclohexyl)amino]carbonyl]-4-[2-[[(methyl-2-pyridylamino)carbonyl]amino]ethyl]benzenesulphonamideN-[[(4-methylcyclohexyl)amino]carbonyl]-4-[2-[[(methyl-2-pyridylamino)carbonyl]amino]ethyl]benzenesulphonamideBenzenesulfonamide, N-[[(4-methylcyclohexyl)amino]carbonyl]-4-[2-[[(methyl-2-pyridinylamino)carbonyl]amino]ethyl]-
물성
구조 계산 물성
- XLogP
- 3.5
- 극성 표면적
- 129 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 33
- 형식 전하
- 0
- 복잡도
- 740
물리화학적 성질
- 밀도
- 1.3 · 1.30±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 5.13 · 5.13±0.10(Predicted)
화학 및 산업
공급사1 곳
Lanospharma Laboratories Co.,Ltd13440048448 · [email protected]
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