4-Hydroxybenzoic acid hydrazide (HCID 1742)

개요

4-hydroxybenzohydrazide is a carbohydrazide obtained by formal condensation of the carboxy group of 4-hydroxybenzoic acid with hydrazine. It is a member of phenols and a carbohydrazide. It is functionally related to a 4-hydroxybenzoic acid.

이름 및 식별자

우선 이름: 4-Hydroxybenzoic acid hydrazide
IUPAC: 4-hydroxybenzohydrazide
영어명: 4-Hydroxybenzhydrazide
분자식: C7H8N2O2
분자량: 152.15

이름 및 동의어

4-hydroxybenzhydrazide4-Hydroxybenzohydrazide5351-23-54-Hydroxybenzoic acid hydrazide4-Hydroxybenzoylhydrazinep-Hydroxybenzoic acid hydrazideY4G7G6U5GQpara-Hydroxybenzoic acid hydrazideNSC-647DTXSID90201721RefChem:524006DTXCID20124212

이름 더 보기

PAHBAHDK841NSC647NSC 647ST50461904OHPhCON2AIDS009023EU-0100568(4-Hydroxyb

226-326-54-Hydroxybenzoic hydrazidep-HydroxybenzhydrazideBenzoic acid, 4-hydroxy-, hydrazide(p-Hydroxybenzoyl)hydrazinep-Hydroxybenzoic hydrazideMFCD000076054-Oxidanylbenzohydrazide

데이터베이스 식별자

CAS: 5351-23-5
PubChem CID: 1742
DTXSID: DTXSID90201721
ChEMBL: CHEMBL124267
ChEBI: CHEBI:195425
UNII: Y4G7G6U5GQ
EC Number: 226-326-5
Nikkaji: J5.203E

물성

구조 계산 물성

XLogP: -0.3
극성 표면적: 75.4 Å²
수소 결합 공여자 수: 3
수소 결합 수용자 수: 3
회전 가능 결합 수: 1
무거운 원자 수: 11
형식 전하: 0
복잡도: 141

실험 및 물리화학적 성질

LogP-0.33

Solubility22.4 [ug/mL] (The mean of the results at pH 7.4)

Endocrine DisruptorsPotential endocrine disrupting compound

물리화학적 성질

녹는점: 264 · 264-266 °C (dec.)(lit.)
끓는 점: 274.61 °C · 274.61°C (rough estimate)
밀도: 1.2804 · 1.2804 (rough estimate)
굴절률: 1.52 · 1.5200 (estimate)
저장 조건: 15 °C · Store at +15°C to +25°C.
용해도: 26.5 g/L · 26.5g/L
물리적 상태: 미세 결정성 분말
산도 계수 (pKa): 8.57 · 8.57±0.15(Predicted)
색상: 흰색에서 약간 베이지색
생물학적 소스: synthetic
수용성: 26.5 g/L · 26.5g/L
BRN: 473052 · 473052
InChI: 1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)
InChIKey: ZMZGIVVRBMFZSG-UHFFFAOYSA-N
SMILES: NNC(=O)c1ccc(O)cc1
NIST: P-hydroxybenzoic acid, hydrazide(5351-23-5)

화학적 성질

white to slightly beige fine crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 08-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22867

Benzoic acid, 4-hydroxy-, hydrazide: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (98%)

안전 데이터

wgk: 3
HS 번호: 29280090
risk_code: 36/37/38
hazard_code: Xi,C
safety_code: 26-36-37/39
위험 등급: IRRITANT
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 1건

용도4-Hydroxybenzhydrazide is a reagent for the rapid automated determination of serum glucose.It can be used as an indicator for the determination of carbohydrates. The acid-hydrolyzable side chains of tissue (liver) bound 4-Hydroxybenzhydrazide can be used as markers to monitor its residues in chickens.