기본 정보
- CAS
98717-15-8- 표준 SMILES
CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl- InChIKey
NDNSIBYYUOEUSV-RSAXXLAASA-N- 분자식
- C17H27ClN2O
- 평균 분자량
- 310.9 g/mol
- 단동위원소 질량
- 310.1811912
이름 및 식별자
- 우선 이름
- Ropivacaine Hydrochloride
- IUPAC
- (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride
- 현지명
- 로피바카인염산염
- 영어명
- Ropivacaine hydrochloride
- 분자식
- C17H26N2O.ClH
- 분자량
- 310.86
이름 및 동의어
Ropivacaine hydrochlorideROPIVACAINE HCl98717-15-8Ropivacaine monohydrochlorideDTXSID204837935504LBE2TDTXCID2028353ROPIVACAINE HYDROCHLORIDE [MI]ROPIVACAINE HYDROCHLORIDE [MART.]ROPIVACAINE HYDROCHLORIDE ANHYDROUSROPIVACAINE HYDROCHLORIDE [WHO-DD]2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride, (S)-
이름 더 보기
로피바카인염산염S-ROPIVACAINE HCLRopivacaine mesilateRopivacaine hydrochlROPIVCACAINE HYDROCHLORIDERopivacaine HCl (anhydrous)(S)-ROPIVACAINE HYDROCHLORIDE
(S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE(S)-(-)-1-PROPYLPIPERIDINE-2-CARBOXYLIC ACID (2,6-DIMETHYLPHENYL)AMIDE HYDROCHLORIDEROPIVACAINE HYDROCHLORIDE (MART.)ROPIVACAINE HYDROCHLORIDE [VANDF]ROPIVACAINE HYDROCHLORIDE [ORANGE BOOK]ROPIVACAINE HYDROCHLORIDE (USP MONOGRAPH)ROPIVACAINE HYDROCHLORIDE [USP MONOGRAPH]ROPIVACAINE HYDROCHLORIDE MONOHYDRATE [MI]
데이터베이스 식별자
- CAS
98717-15-8- PubChem CID
- 175804
- DTXSID
DTXSID2048379- ChEMBL
CHEMBL1889140- UNII
- 35504LBE2T
- EC Number
- 691-259-4
물성
구조 계산 물성
- 극성 표면적
- 32.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 21
- 형식 전하
- 0
- 복잡도
- 308
물리화학적 성질
- 녹는점
- 260 · 260-262°
- 저장 조건
- -20 °C · Store at -20°C
- 물리적 상태
- Solid
- 색상
- White to off-white
- 수용성
- 10.1 mg/mL · ≥ 10.1mg/mL in Water
- 주요 응용
- 소분자 약용
- InChI
- InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H
- InChIKey
- NDNSIBYYUOEUSV-UHFFFAOYSA-N
- SMILES
- N1(CCC)CCCCC1C(NC1=C(C)C=CC=C1C)=O.[H]Cl
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
안전 데이터
- wgk
- WGK 3
- Hazard Classifications
- Eye Dam. 1
- 스토리지 클래스
- 13 - Non Combustible Solids
화학 및 산업
약리 정보
FDA Pharmacological Classification
ROPIVACAINE HYDROCHLORIDE
Amide Local Anesthetic [EPC]; Amides [CS]; Local Anesthesia [PE]
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
응용 분야
용도anesthetic
상·하류 제품 정보
하류 제품
공급사101 곳
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
江苏艾康生物医药研发有限公司
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