4-아미노-1-나프톨
4-아미노-1-나프톨 · 1-Amino-4-naphthol · 4-amino-1-naphthol · 4-Amino-1-naphthalenol · 4-azanylnaphthalen-1-ol · 1-Amino-4-hydroxynaphthalene
식별자 및 물리적 특성
| CAS No. | 2834-90-4 |
|---|---|
| 분자식 | C10H9NO |
| 평균 분자량 | 159.18 g/mol |
| 단동위원소 질량 | 159.06841391 g/mol |
| SMILES | Nc1ccc(O)c2ccccc12 |
| InChIKey | ABJQKDJOYSQVFX-UHFFFAOYSA-N |
| PubChem CID | 17815 |
| ChEMBL | CHEMBL576321 |
| EC No. | 621-191-2 |
| DTXSID | DTXSID30182580 |
| 현지명 | 4-아미노-1-나프톨 |
화학 및 물리적 성질
| XLogP | 2.6 |
|---|---|
| 극성 표면적 | 46.3 |
| 수소 결합 공여자 수 | 2 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 160 |
화학적 성질
Acicular crystals. Soluble in water.
안전 및 규제
| GHS 분류 | DangerH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| 신호 어 | Danger |
| 유해·위험 문구 | 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H302 |
용도
용도
Inhibitor of polymerization, chemical intermediate. Must be kept dry during storage to avoid oxidation and discoloration.
제조 및 합성 방법
생산 방법
Orange I in aqueous alkaline solution is treated with sodium dithionite at 40 – 50℃, and the resulting suspension is heated to 70℃ to complete the reaction. The crude product is collected by filtration and dissolved in hot aqueous hydrochloric acid in the presence of a reducing agent. On cooling, needles of the hydrochloride salt crystallize and can be isolated in 70 % yield. Alternatively, the crude paste may be dissolved in dilute alkali in the presence of a reducing agent and acylated with acetic anhydride or acryloyl chloride, for example, to give 4- acetylamino-1-naphthol or 4-acryloylamino-1- naphthol, which have been used as azo coupling components.