CAS 351-50-8 D-Histidine (HCID 178511802)

이름 및 식별자

우선 이름: D-Histidine
IUPAC: (2R)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
영어명: D-Histidine
분자식: C6H9N3O2
분자량: 155.15

이름 및 동의어

D-Histidine351-50-8(R)-2-Amino-3-(1H-imidazol-4-yl)propanoic acidD-Histidin(2R)-2-amino-3-(1H-imidazol-4-yl)propanoic acid(2R)-2-amino-3-(1H-imidazol-5-yl)propanoic acidD-Histamine4JE5HRM5CH(r)-histidineCHEBI:27947HISTIDINE, D-EINECS 206-513-8

이름 더 보기

D-HISD-HIS-OHD-Histdine99.0%(T&HISTIDINE, D-D-Histidine>D-Histidine,99%D-Histidine ,98%

DTXSID70889344(R)-alpha-Amino-1H-imidazole-4-propionic acidRefChem:583868DTXCID101028606(2R)-2-azaniumyl-3-(1H-imidazol-5-yl)propanoate(2R)-2-amino-3-(1H-imidazol-4-yl)propanoic acid;D-histidineH-D-His-OHMFCD00065963

데이터베이스 식별자

CAS: 351-50-8
PubChem CID: 71083

물성

구조 계산 물성

XLogP: -3.2
극성 표면적: 92 Å²
수소 결합 공여자 수: 3
수소 결합 수용자 수: 4
회전 가능 결합 수: 3
무거운 원자 수: 11
형식 전하: 0
복잡도: 151

물리화학적 성질

녹는점: 280 °C · 280 °C
끓는 점: 278.95 °C · 278.95°C (rough estimate)
밀도: 1.3092 · 1.3092 (rough estimate)
굴절률: -13 ° · -13 ° (C=11, 6mol/L HCl)
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
용해도: 1 M · 1M HCl: 용해성
물리적 상태: 자유 유동 분말
산도 계수 (pKa): 1.91 · 1.91±0.10(Predicted)
색상: 하얀색
수용성: 42 g/L · 42g/L(25℃)
Merck: 14 · 14,4720
BRN: 84089 · 84089
안정성: 흡습성
주요 응용: 발각펩타이드 합성
InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m1/s1
InChIKey: HNDVDQJCIGZPNO-RXMQYKEDSA-N
SMILES: N[C@H](Cc1c[nH]cn1)C(O)=O
LogP: -1.27 · -1.270
EPA: D-Histidine (351-50-8)

화학적 성질

white crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 80% (4 of 5) of all reports.

Warning

H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (20%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (20%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 4 of 5 reports by companies.；There is 1 notification provided by 1 of 5 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (20%)；Eye Irrit. 2A (20%)；STOT SE 3 (20%)

안전 데이터

wgk: 3
tsca: TSCA listed
HS 번호: 29332900
hazard_code: Xn
safety_code: 22-24/25-36/37-26
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing InformationD-Histidine: INACTIVE

응용 분야

용도D-Histidine is the unnatural, biologically inactive isomer of L-Histidine (H456010). D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine.