CASPASE-1

용도Caspase 1 human has been used in in vitro cleavage assay with Rab interacting lysosomal protein (RILP) and in the cleavage of caspases-3/7 in human monocyticcells (THP1).

일반 설명Caspase 1, also called interleukin (IL)-1-converting enzyme, is mapped to human 11q22.3. It belongs to the aspartate-specific cysteine proteases family and is primarily synthesized as procaspase-1 zymogen, which later become catalytically active post autoproteolysis. The enzymatically active caspase-1 comprises two p20/p10 heterodimer making it a tetramer.