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크롬칼륨황산염12HYDR

Sulfuric acid, chromium(3+) potassium salt (2:1:1)

HCID 178709144
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
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기본 정보

CAS
10141-00-1
표준 SMILES
O=S(=O)([O-])[O-].O=S(=O)([O-])[O-].[Cr+3].[K+]
InChIKey
OIDPCXKPHYRNKH-UHFFFAOYSA-J
분자식
CrKO8S2
평균 분자량
283.22 g/mol
단동위원소 질량
282.80767

개요

Chromium(III) potassium sulfate is a sulfate of chromium and potassium. It can be used for leather tanning. Chromium is a chemical element which has the symbol Cr and atomic number 24. It is found naturally occuring in rocks, animals, plants, and soil, and is usually mined as chromite ore. Chromium is most toxic in its +6 oxidation state (chromium(VI)) due to its greater ability to enter cells and higher redox potential. Trivalent chromium (chromium(III)) however, is biologically necessary for sugar and lipid metabolism in humans. (L17, L514)

이름 및 식별자

우선 이름
Sulfuric acid, chromium(3+) potassium salt (2:1:1)
IUPAC
potassium;chromium(3+);disulfate
현지명
크롬칼륨황산염12HYDR
영어명
CHROMIUM POTASSIUM SULFATE 12HYDR
분자식
CrKO8S2
분자량
283.2196

이름 및 동의어

10141-00-1Potassium chromic sulfateChromic potassium sulphatePotassium chromic sulphateCHROMIC POTASSIUM SULFATE0% Basicity chrome alumSulfuric acid, chromium(3+) potassium salt (2:1:1)Chromium potassium sulfate (CrK(SO4)2)579U79PAICPotassium chromium disulfate (KCr(SO4)2)DTXSID00890645chromalum
이름 더 보기
크롬칼륨황산염12HYDRCHROMIUM POTASSIUM SULFATE 12HYDR
RefChem:576866DTXCID301030930233-401-6Chrome alumChromium potassium sulfateChromium potassium bis(sulphate)10279-63-7Chromium(III) potassium sulfate

데이터베이스 식별자

CAS
10141-00-1、10279-63-7、7788-99-0
PubChem CID
61489
UNII
579U79PAIC
EC Number
233-401-6、233-627-5、616-539-5

물성

구조 계산 물성

극성 표면적
177 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
8
회전 가능 결합 수
0
무거운 원자 수
12
형식 전하
0
복잡도
62.2

실험 및 물리화학적 성질

Chemical ClassesMetals -> Chromium Compounds, Inorganic
Food Contact Substances · 2건

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physical DescriptionViolet-red crystals; soluble in water; [Hawley] Red-violet odorless granules; [Mallinckrodt Baker MSDS]

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 75% (3 of 4) of all reports.

Warning

유해성 정보

Regulatory Information · 4건

Chemical: Sulfuric acid, chromium(3+) potassium salt (2:1:1)

REACH registered substance: Chromium potassium bis(sulphate) (EC: 233-401-6)

Sulfuric acid, chromium(3+) potassium salt (2:1:1): Does not have an individual approval but may be used under an appropriate group standard

Sulfuric acid, chromium potassium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1건

CrIII compounds do not cause chrome ulcerations but may cause allergic dermatitis in workers with prior sensitization to CrVI compounds. [ILO Encyclo] CrIII is an essential trace mineral in the human diet. [ATSDR Case Studies] An irritant that may causes skin ulcerations and eye injury on prolonged contact; Harmful by ingestion and inhalation; [Mallinckrodt Baker MSDS] See Chromium.

Hazard Classes and Categories · 2건

Skin Irrit. 2 (100%)

Skin Irrit. 2 (25%)

안전 및 보호

Threshold Limit Values (TLV)

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Chromium is absorbed from oral, inhalation, or dermal exposure and distributes to nearly all tissues, with the highest concentrations found in kidney and liver. Bone is also a major storage site and may contribute to long-term retention. Hexavalent chromium's similarity to sulfate and chromate allow it to be transported into cells via sulfate transport mechanisms. Inside the cell, hexavalent chromium is reduced first to pentavalent chromium, then to trivalent chromium by many substances including ascorbate, glutathione, and nicotinamide adenine dinucleotide. Chromium is almost entirely excreted with the urine. (A12, L16)

용도 및 제조

Uses · 3건

Used in dyeing (mordant), tanning, printing calico, developing photographs, and producing glue, gum, waterproof fabrics, inks, and other chromium compounds; [Merck Index]

Leather Tanning and Processing [Category: Industry]

Chromium(III) potassium sulfate can be used for leather tanning. (L514)

General Manufacturing Information · 2건

Sulfuric acid, chromium(3+) potassium salt (2:1:1): ACTIVE

Sulfuric acid, chromium potassium salt (1:?:?): ACTIVE

관련 반응

0건
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화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
0.003 [mg/m3], as Cr(III), inhalable particulate matter
Permissible Exposure Limit (PEL)0.5 [mg/m3]

독성 정보

TreatmentThere is no know antidote for chromium poisoning. Exposure is usually handled with symptomatic treatment. (L16)
Health EffectsChromium in its trivalent state is not very toxic. It may be oxidized to hexavalent chromium, a known carcinogen. Hexavalent chromium has also been shown to affect reproduction and development. (A12)
Adverse EffectsACGIH Carcinogen - Not Classifiable.
Exposure RoutesOral (L16) ; inhalation (L16) ; dermal (L16)
Toxicity Summary · 1건

Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36)

Signs and Symptoms · 1건

Chromium in its trivalent state is not very toxic, but it may be oxidized to hexavalent chromium. Breathing hexavalent chromium can cause irritation to the lining of the nose, nose ulcers, runny nose, and breathing problems, such as asthma, cough, shortness of breath, or wheezing. Ingestion of hexavalent chromium causes irritation and ulcers in the stomach and small intestine, as well as anemia. Skin contact can cause skin ulcers. (L16)

Carcinogen Classification3, not classifiable as to its carcinogenicity to humans. (L135)