기본 정보
- CAS
182683-50-7- 표준 SMILES
CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@@H](C)O- InChIKey
KNTBAGOTDJPUJV-XMTFRXHISA-N- 분자식
- C37H65N9O13
- 평균 분자량
- 844 g/mol
- 단동위원소 질량
- 843.47018316
이름 및 식별자
- 우선 이름
- Epsilon-V1-2
- IUPAC
- (4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
- 영어명
- PKCε Inhibitor Peptide
- 분자식
- C37H65N9O13
- 분자량
- 843.96
이름 및 동의어
Epsilon-V1-2182683-50-7PKCepsilon Inhibitor PeptideL-alpha-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonine(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acidCHEMBL3261358Peptide epsilonV1-2Epsilon-V1-2?PKC|A Inhibitor Peptideorb1694277SCHEMBL30544033GLXC-21454
이름 더 보기
ε-V1-2epsilonV1-2KNTBAGOTDJPUJV-XMTFRXHISA-NL-a-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonineL-α-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonineL-Threonine, L-α-glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-
HY-P0154BDBM50012948MFCD01076534AKOS040754861L-|A-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonineH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OHDA-63243MS-31563
데이터베이스 식별자
- CAS
182683-50-7- PubChem CID
- 10147482
- ChEMBL
CHEMBL3261358- Nikkaji
- J1.664.260F
물성
구조 계산 물성
- XLogP
- -6.9
- 극성 표면적
- 362 Ų
- 수소 결합 공여자 수
- 12
- 수소 결합 수용자 수
- 15
- 회전 가능 결합 수
- 26
- 무거운 원자 수
- 59
- 형식 전하
- 0
- 복잡도
- 1,480
물리화학적 성질
- 끓는 점
- 1280.1 · 1280.1±65.0 °C(Predicted)
- 밀도
- 1.288 · 1.288±0.06 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 10 mg/ml; · DMSO: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 3.28 · 3.28±0.10(Predicted)
- 색상
- White to off-white
화학 및 산업
응용 분야
용도L-α-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonine selectively and reversibly inhibits the translocation of PKC to intracellular membranes, blocking activation. It is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase.
공급사29 곳
Aladdin Scientific[email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
杭州专肽生物技术有限公司17342063383 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
风咏生物（AbMole）021-10000000 13000000000 · [email protected]
成都云希化工有限公司+86-17380623303 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
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杭州肽佳生物科技有限公司0571-87213919 15967184799 · [email protected]
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浙江杰坤生物科技有限公司15397062932 · [email protected]
雷丁科技0510-85629785 18013409632 · [email protected]
南京源肽生物科技有限公司13357818155 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
南京肽研生物科技有限公司19961912513 19941518170 · [email protected]
武汉科斯坦生物科技有限公司027-65317797 15926423062 · [email protected]
北京索莱宝科技有限公司17801761073 18101056239 · [email protected]
绍兴市均宇生物科技有限公司0571-0571-88211921 19105816207 · [email protected]
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