폴리(에틸렌옥사이드)-에틸렌-D4옥사이드

Move container from fire area if you can do so without risk. Stay away from ends of tanks. Fight fire from maximum distance. For massive fire in cargo area, use unmanned hose holder or monitor nozzles; if this is impossible, withdraw from area and let fire burn. Withdraw immediately in case of rising sound from venting safety device or any discoloration of tank due to fire. Isolate for 1 mile in all directions if tank car or truck is involved in fire. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Wear positive pressure breathing apparatus and full protective clothing. Evacuate area endangered by gas.

Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with powder, alcohol-resistant foam, water spray, carbon dioxide. In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position.

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

Warning: Ethylene oxide is corrosive to moist tissues. Caution is advised.

General First Aid:

(General first aid procedures)

· Wear positive pressure self-contained breathing apparatus (SCBA).

Biological Exposure Indices (BEI) [ACGIH] - N-(2-hydroxyethyl)valine (HEV) hemoglobin adducts = 5000 pmol HEV/g globin. See urine BEI and further details. [TLVs and BEIs]

GAS: Poisonous gases are produced in fire. Do not estinguish the fire unless the flow of gas can be stopped and any remaining gas is out of the line. Specially trained personnel may use fog lines to cool exposures and let the fire burn itself out. Vapors are heavier than air and will collect in low areas. Vapors may travel long distances to ignition sources and flashback. Vapors in confined area may explode in fire. Storage containers and parts of containers may rocket great distances, in many directions. If materials or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows any signs of deforming), withdraw immediately to a secure position. If employees are expected to fight fires, they must be trained and equipped. LIQUID: Poisonous gases are produced in fire. Use dry chemical, carbon dioxide, or foam extinguishers. Although soluble in water, solutions will continue to burn until diluted to approximately 22 volumes of water to one volume of ethylene oxide. Vapors are heavier than air and will collect in low areas. Vapors may travel long distances to ignition sources and flashback. Vapors in confined area may explode in fire. Storage containers and parts of containers may rocket great distances, in many directions. If materials or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows any signs of deforming), withdraw immediately to a secure position. If employees are expected to fight fires, they must be trained and equipped.

Fire extinguishing agents: water.

Stop flow of gas if possible. Combat fires from behind barrier, with unmanned hose holder or monitor nozzle. Flood discharge area with water. Cool exposed containers and protect men effecting shut off with water.

Carbon dioxide and dry-chemical extinguishers are useful against small fire.

For more Fire Fighting Procedures (Complete) data for ETHYLENE OXIDE (8 total), please visit the HSDB record page.

Prior to working with this chemical you should be trained on its proper handling and storage. Before entering a confined space where this chemical may be present, check to make sure that an explosive concentration does not exist. It must be stored to avoid contact with even small amounts of acids (such as nitric or sulfuric acids); alkalis (such as sodium bydroxide or potassium hydroxide); cataylic anhydrous chlorides of iron, aluminum or tin; iron or aluminum oxide; or metallic potassium hydroxide); catalytic anhydrous chlorides of iron, aluminum or tin; iron or aluminum oxide; or metallic potassium hydroxide, since it may react by itself, liberating much heat and causing a possible explosion. Ethylene oxide should not contact oxidizers (such as perchlorates, perxoides, permanganates, chlorates, and nitrates) since an explosion could occur. Store in tightly closed containers in a cool, well-ventilated area away from heat, sparks, or sunlight. Sources of ignition such as smoking and open flames are prohibited where ethlyene oxide is handled, used, or stored. Metal containers involving the transfer of 5 gallons or more of ethylene oxide should br grounded and bonded. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only non-sparking tools and equipment, especially when opening and closing containers of ethylene oxide . Wherever ethylene oxide is used, handled, manufactured, or stored, use explosion-proof electrical equipment and fittings.

Store EtO in tightly closed cylinders or tanks in a cool, shaded, well-ventilated, explosion-proof area.

Temperature: ambient

Protect containers against physical damage, check for leakage intermittently. Store in distant outdoor tank or container protected from direct sunlight, lined with insulating material, equipped with an adequate refrigeration and water system. Indoor storage should be restricted to small quantities. Place material in a combustible liquid cabinet which is fireproof in conformity with regulations.

For more Storage Conditions (Complete) data for ETHYLENE OXIDE (7 total), please visit the HSDB record page.

GAS: Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Stop the flow of gas if it can be done safely. If source of leak us a cylinder and the leak cannot be stopped in place, remove leaking cylinder to a safe place in the open air, and repair leak or allow cylinder to empty. Keep this chemical out of a confined space, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build-up of explosive concentrations. LIQUID: For small spills flush area with flooding amounts of water. For large spills, dike spill for later disposal. Absorb liquids in vermiculite, dry sand, earth, or a similar non-organic materials and deposit in sealed containers. May also be covered with weak reducing agents; resulting sludge neutralized and flushed to sewer. Collect powdered material in the most convenient and safe manner and deposit in sealed containers. Ventilate area of spill or leak after clean-up is complete. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean-up spills, they must be properly trained and equipped.

Shut off ignition sources and call fire dept. Stop /flow/ if possible. Stay upwind and use water spray to "knock down" vapor. Isolate and remove discharged material. Notify local health and pollution control agencies.

PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. /Chemical Carcinogens/

Eliminate all ignition sources. Releases may require isolation or evacuation. Approach release from upwind. Stop or control the leak, if this can be done without undue risk. Use water spray to cool and disperse vapors, protect personnel, and dilute spills to form nonflammable mixtures. Water solutions no longer flammable in open areas when diluted as 1 part in 22 parts water. In enclosed areas such as sewers, dilution to 1 part in 100 parts water may be required to eliminate flash potential. Control runoff and isolate discharged material for proper disposal.

[40 CFR 240-280, 300-306, 702-799 (7/1/2006)] Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U115, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

Concentrated waste containing no peroxides-discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxides-perforation of a container of the waste from a safe distance followed by open burning.

A good candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A good candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.

Evaporation & open burning: A) Place on ground in an open area. Evaporate or burn by igniting from a safe distance. B) Dissolve in benzene, petroleum ether or higher alcohol such as butanol. Dispose by burning the soln. Recommendable method: Incineration. Peer review: Ethylene oxide boils @ 11 °C, therefore burning in an incinerator can cause difficulties unless a gas feed can be arranged. It is soluble in water or alcohol and these soln can be burned. (Peer-review conclusions of an IRPTC expert consultation (May 1985))

For more Disposal Methods (Complete) data for ETHYLENE OXIDE (9 total), please visit the HSDB record page.

Immune

[peritoneal cancer, leukemia]

Cell transformation in vitro of C3H/10T1/2 cells, using gamma-radiation and ethylene oxide, in both the absence and presence of the cancer promoter, 12-O-tetradecanoylphorbol-13- acetate, was studied. 12-O-tetradecanoylphorbol-13-acetate promotes transformation of C3H/10T1/2 cells to the same extent. In the dose ranges studied the average enhancement of the transformation frequency was 2.4 and 2.5 for ethylene oxide and gamma-radiation, respectively. The rad-equivalence of ethylene oxide in the presence of 12-O-tetradecanoylphorbol-13-acetate was calculated to be 75 + or - 52 rad/mMh (95% confidence interval) which is consistent with the value 78 + or - 14 rad/mMh (95% confidence interval) obtained without 12-O-teradecanoylphorbol-13-acetate treatment.

Cancer, Developmental (effects during periods when organs are developing) , Endocrine (Glands and Hormones), Hematological (Blood Forming), Neurological (Nervous System), Reproductive (Producing Children), Respiratory (From the Nose to the Lungs)

Eyes, skin, respiratory system, liver, central nervous system, blood, kidneys, reproductive system

At high doses (>200 ppm) ethylene oxide irritates mucous membranes of the nose and throat; higher concentrations cause damage to the trachea and bronchi, progressing into the partial collapse of the lungs. High concentrations can cause pulmonary edema and damage the cardiovascular system. Because the odor threshold for ethylene oxide varies between 250 and 700 ppm, the gas will already be at toxic concentrations when it can be smelled. Ethylene oxide is carcinogenic, mutagenic and an irritant. With chronic low doses, an increased incidence of brain tumors and mononuclear cell leukemia was found in rats that had inhaled ethylene oxide at concentrations of 10, 33, or 100 mL/m3 over a period of two years. Studies of workers exposed to ethylene oxide in ethylene oxide factories or hospital sterilizing rooms have shown an increased incidence of leukemia, stomach cancer, cancer of the pancreas and Hodgkin's disease.

LC50; Species: Artemia sp. (Brine shrimp); Conditions: saltwater, static; Concentration: 350000 ug/L for 24 hr /formulated product/

LC50; Species: Artemia sp. (Brine shrimp); Conditions: saltwater, static; Concentration: 490000 ug/L for 48 hr /formulated product/

LC50; Species: Daphnia magna (Water flea); Conditions: freshwater, static; Concentration: 260000 ug/L for 24 hr /formulated product/

LC50; Species: Daphnia magna (Water flea); Conditions: freshwater, static; Concentration: 137000 ug/L for 48 hr (95% confidence interval: 83000-179000 ug/L) /formulated product/

For more Ecotoxicity Values (Complete) data for ETHYLENE OXIDE (10 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), a Koc value of 2.2(2), indicates that ethylene oxide is expected to have very high mobility in soil(SRC). Volatilization of ethylene oxide from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 1.48X10-4 atm-cu m/mole(3). Ethylene oxide is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 1.31X10+3 mm Hg(4). Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in the environment is not able to be accurately assessed(3).

AQUATIC FATE: Based on a classification scheme(1), a Koc value of 2.2(2), indicates that ethylene oxide is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 1.48X10-4 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 6 hours and 4 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 3(SRC), from its log Kow of -0.30(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in the environment is not able to be accurately assessed(4).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethylene oxide, which has a vapor pressure of 1.13X10+3 mm Hg at 25 °C(2), is expected to exist solely as a gas in the ambient atmosphere. Gas-phase ethylene oxide is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 57 days(SRC), calculated from its rate constant of 7.6X10-14 cu cm/molecule-sec at 25 °C(3). Ethylene oxide does not contain chromophores that absorb at wavelengths >290 nm(4) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC). In a smog chamber experiment, 20% of the ethylene oxide degraded in 5.3 hr(5).

The substance can be absorbed into the body by inhalation and through the skin.

inhalation, ingestion, (liquid), skin and/or eye contact

Inhalation, Dermal

IDENTIFICATION: Ethylene oxide is a colorless, high reactive gas at room temperature and pressure. It used in the manufacture of ethylene glycol and surfactants. It used in the manufacture of surfactants. Ethylene oxide is also used as a sterilant for health care materials and other heat-sensitive products. HUMAN EXPOSURE: Ethylene oxide is rapidly taken up via the lungs, distributed, and metabolized to ethylene glycol and to glutathione conjugates. Ethylene oxide can be absorbed though the skin from the gas phase or from aqueous solutions and is uniformly distributed throughout the body. Ethylene oxide is an alkylating agent and forms protein and DNA adducts. Hemoglobin adducts have been used for biomonitoring. Based on studies primarily in occupationally exposed populations, ethylene oxide is an ocular, respiratory, and dermal irritant and a sensitizing agent. Neurological effects (primarily sensorimotor polyneuropathy) have been observed in workers exposed to relatively high concentrations. The route of likely greatest exposure and focus of the human health is inhalation from air. There is some evidence of an association between exposure to ethylene oxide and the development of haematological cancers in epidemiological studies of occupationally exposed populations, limitations of the data preclude definitive conclusions. There is consistent evidence that ethylene oxide has induced clastogenic changes in exposed workers. ANIMAL/PLANT STUDIES: The acute inhalation toxicity of ethylene oxide in rodents and dogs is low. In inhalation studies, ethylene oxide has induced a wide range of tumours (e.g., leukaemia, lymohoma, brain, lung). Ethylene oxide induces gene mutations at all phylogenetic levels tested in vitro and in vivo. It also induces germ cell mutations and clastogenic effects in experimental animals. In experimental animals, ethylene oxide is fetotoxic in the presence and absence of maternal toxicity at concentrations higher than those associated with cancer and other non-cancer (i.e., neurological) effects; it is teratogenic only at very high concentrations (above about 1600 mg/m3). Evidence from epidemiological studies of reproductive effects (primarily spontaneous abortions) of ethylene oxide in humans is limited. In experimental animals, among non-neoplastic effects, reproductive effects occur at lowest concentration (>90 mg/m3). These include reductions in litter size, increased post-implantation losses, alterations in sperm morphology, and changes in sperm count and motility. Available data on the non-neoplastic effects of repeated exposure to ethylene oxide in studies are limited, with past focus being primarily on the carcinogenicity of the compound. Reported effects in studies in animals were restricted primarily to those on the hematological and nervous systems.

Ethylene oxide is an alkylating agent. The addition of alkyl groups to proteins, DNA, and RNA by binding to the sulfhydryl and hydroxyl, amino, and carboxyl groups, prevents normal cellular metabolism and ultimately kills cells. It is likely that the carcinogenicity of ethylene oxide in laboratory animals arises primarily as a result of its direct alkylation of DNA and RNA. In vivo exposure to ethylene oxide induced mutations (5- to 5.6-fold) at the Hprt locus in splenic T-lymphocytes in rats and mice.

U115; As stipulated in 40 CFR 261.33, when ethylene oxide, as a commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate, becomes a waste, it must be managed according to Federal and/or State hazardous waste regulations. Also defined as a hazardous waste is any residue, contaminated soil, water, or other debris resulting from the cleanup of a spill, into water or on dry land, of this waste. Generators of small quantities of this waste may qualify for partial exclusion from hazardous waste regulations (40 CFR 261.5).

Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. Oxirane is included on this list. Effective date: 10/4/82; Sunset date: 10/4/92.

Tolerances are established for residues of the antimicrobial agent and insecticide ethylene oxide, when used as a postharvest fumigant in or on the following food commodities: [Table#606]

Ethylene oxide may be safely used as a fumigant for the control of microorganisms and insect infestation in ground spices and other processed natural seasoning materials, except mixtures to which salt has been added, in accordance with the following prescribed conditions: (i) Ethylene oxide, either alone or admixed with carbon dioxide or dichlorodifluoromethane, shall be used in amounts not to exceed that required to accomplish the intended technical effects. If used with dichlorodifluoromethane, the dichlorodifluoromethane shall conform with the requirements prescribed by 21 CFR 173.355 of this chapter. (ii) To assure safe use of the fumigant, its label and labeling shall conform to that registered with the U.S. Environmental Protection Agency and it shall be used in accordance with such label or labeling. (iii) Residues of ethylene oxide in ground spices from both postharvest application to whole spices and application to the ground spices shall not exceed the established tolerance of 50 parts per million for residues in whole spices in paragraph (a)(1) of this section.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Ethylene oxide is found on List A, which contains most food use pesticides and consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA, as amended in 1988. Case No: 2275; Pesticide type: insecticide, fungicide, rodenticide, antimicrobial; Case Status:In Pre-Special Review. The pesticide is in or has completed the reregistration process and, meanwhile, is also the subject of an in-depth Special Review.; Active ingredient (AI): Ethylene oxide; Data Call-in (DCI) Date(s): 05/24/91; AI Status: The producers of the pesticide has made commitments to conduct the studies and pay the fees required for reregistration, and are meeting those commitments in a timely manner.

This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Ethylene oxide is produced, as an intermediate or a final product, by process units covered under this subpart.

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Ethylene oxide is included on this list.

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 10 lb or 4.54 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Ethylene oxide is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 1,000 lbs.

Ethylene oxide

1

10000

Flammable chemical that can be released at a facility.

Ethylene oxide is used mainly as a chemical intermediate in the manufacture of ethylene glycol (antifreeze), textiles, detergents, polyurethane foam, solvents, medicine, adhesives, and other products.

Ethylene oxide sterilizers are used by medical and dental staff to sterilize heat-sensitive instruments. [p. 736, Harber] Occupational asthma from ethylene oxide has been reported in a nurse. [Malo]

Sterilizing Equipment [Category: Clean]

/In the/ manufacture of ethylene glycol and higher glycols, surfactants, acrylonitrile, ethanolamines; petroleum demulsifier; fumigant; rocket propellant; industrial sterilant (e.g., medical plastic tubing); fungicide.

For Ethylene oxide (USEPA/OPP Pesticide Code: 042301) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

ETO is an antimicrobial and conventional chemical. It is a biocide, Pesticide: fungicide, fumigant, herbicide, insecticide, rodenticide used to control the following pests: American foulbrood disease (Bacillus larvae), animal pathogenic bacteria, animal pathogenic fungi, bacteria, bacterial spores, Candida albicans, European foulbrood disease (Streptoccus pluton), Herpes simplex virus, Hew (FDA/BVM), unspecified microorganisms, Mycobacterium spp., Nosema apis, Pseudomonas spp., Rhinoviruses, storage microorganisms, stored product insects, wax moth. ... ETO is used to sterilize medical or laboratory equipment, pharmaceuticals, and aseptic packaging ... or to reduce microbial load on musical instruments, cosmetics, whole and ground spices or other seasoning materials ... and artifacts, archival material or library objects. In North Carolina, ETO is also used to fumigate beehive equipment (eg, woodenware boxes and frames) and wax or plastic combs that are contaminated with the bacteria Paenibacillus larvae, the cause of American Foulbrood Disease.

(1978) 3.46X10+10 G

(1983) 6.27X10+9 G

(1985) 2.82X10+10 g

CHEMICAL PROFILE: Ethylene Oxide. US Exports: 1994: 27 million pounds

For more U.S. Exports (Complete) data for ETHYLENE OXIDE (8 total), please visit the HSDB record page.

(1977) 1.15X10+10 G

(1982) 4.30X10+9 G

(1985) 1.03X10+10 g

CHEMICAL PROFILE: Ethylene Oxide. US Imports: 1994: 32 million pounds

For more U.S. Imports (Complete) data for ETHYLENE OXIDE (8 total), please visit the HSDB record page.

2023: 7,000,000,000 - <8,500,000,000 lb

(1977) 2.03X10+12 G

(1982) 2.26X10+12 G

(1986) 2.49X10+12 g /Estimated/

(1985) 2.58X10+12 g

For more U.S. Production (Complete) data for ETHYLENE OXIDE (20 total), please visit the HSDB record page.

CHEM INT FOR ETHYLENE GLYCOL, 60.5%; CHEM INT FOR NONIONIC SURFACTANTS (ACYCLIC), 7.1%; CHEM INT FOR NONIONIC SURFACTANTS (CYCLIC), 4.6%; CHEM INT FOR GLYCOL ETHERS, 7.2%; CHEM INT FOR ETHANOLAMINES, 7.1%; CHEM INT FOR DIETHYLENE GLYCOL, 5.1%; CHEM INT FOR TRIETHYLENE GLYCOL, 2.1%; CHEM INT FOR POLYETHYLENE GLYCOL, 1.6%; OTHER, 4.7% (1981)

Monoethylene glycol, 59%; higher glycols, 15%; ethoxylates, 10%; ethanolamines, 6%; glycol ethers, 5%; miscellaneous, 5% (1984)

CHEMICAL PROFILE: Ethylene oxide. End-use Pattern for Ethylene Oxide in 1987

CHEMICAL PROFILE: Ethylene oxide. US Demand: 1986: 5.7 billion pounds; 1987: 5.8 billion pounds; 1991: 6.4 billion pounds /projected/

For more Consumption Patterns (Complete) data for ETHYLENE OXIDE (18 total), please visit the HSDB record page.

(1) Oxidation of ethylene in air or oxygen with silver catalyst; (2) action of an alkali on ethylene chlorohydrin.

Prepared from ethylene chlorohydrin and potassium hydroxide ... manufactured by catalytic oxidation of ethylene.

Direct oxidation ... utilizes the catalytic oxidation of ethylene with oxygen over a silver-based catalyst ... .

The process involves the reaction of ethylene with hypochlorous acid followed by dehydrochlorination of the resulting chlorohydrin with lime .... . /Chlorohydrin process/

Ethylene oxide was first produced in the United States in 1921. Until 1937, ethylene oxide was produced by the chlorohydrin process, in which ethylene was treated with hypochlorous acid to produce ethylene chlorohydrin. Calcium hydroxide or sodium hydroxide was used to convert ethylene chlorohydrin to ethylene oxide. Currently in the United States, essentially all production of ethylene oxide uses the direct vapor phase oxidation process. This process oxidizes ethylene with air or oxygen in the presence of a silver catalyst to produce ethylene oxide.

ETO is formulated and marketed as a gas or a pressurized liquid. The end use formulations are all gas mixtures of ETO and inert gases (eg, carbon dioxide) in varying concentrations.

/ETHYLENE OXIDE/ IS MIXED WITH EITHER CARBON DIOXIDE OR FLUOROCARBON 12 ... TO ELIMINATE FLAMMABILITY ... . CARBOXIDE IS NONFLAMMABLE MIXTURE OF 10% BY WT ETHYLENE OXIDE IN CARBON DIOXIDE ... STERILANT 12 IS NONFLAMMABLE MIXT OF 12% BY WT ... IN FLUOROCARBON 12 ... .

Grades or purity: commercial: 100% must contain no acetylene.

GRADES: TECHNICAL; PURE (99.7%).

For more Formulations/Preparations (Complete) data for ETHYLENE OXIDE (35 total), please visit the HSDB record page.

Cosmetics product ingredient: Ethylene oxide (Oxirane)

Information on 66 consumer products that contain Ethylene oxide in the following categories is provided: