2-Aminothiazole

HCID 178786969

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부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 361381-86-4
표준 SMILES: Nc1nccs1
InChIKey: RAIPHJJURHTUIC-UHFFFAOYSA-N
분자식: C3H4N2S
평균 분자량: 100.14 g/mol

개요

2-aminothiazole appears as light brown crystals or brown granular solid. (NTP, 1992)

이름 및 식별자

우선 이름: 2-Aminothiazole
IUPAC: 1,3-thiazol-2-amine
영어명: 2-Aminothiazole
분자식: C3H4N2S
분자량: 100.14226

이름 및 동의어

2-AMINOTHIAZOLEaminothiazole96-50-42-ThiazolamineAbadole2-ThiazolylamineAbadolBasedol2-Thiazylamine4-Thiazolin-2-onimineAminothiazolAminotiazol

이름 더 보기

Thiazole, 2-amino-AminothiazolumUSAF EK-P-5501RP 2921AminotiazoloDTXSID5024508NSC-19005K8WKN668K

데이터베이스 식별자

CAS: 361381-86-4
ChEMBL: CHEMBL344760
ChEBI: CHEBI:40782
UNII: 5K8WKN668K
EC Number: 202-511-6
Nikkaji: J3.972A

물성

구조 계산 물성

XLogP: 0.4
극성 표면적: 67.2 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 6
형식 전하: 0
복잡도: 48.1

실험 및 물리화학적 성질

SpringerMaterials PropertiesChemical shift

LogP0.38

Solubilityless than 1 mg/mL at 68 °F (NTP, 1992)

Boiling PointDecomposes (NTP, 1992)

Melting Point194 °F (NTP, 1992)

Physical Description2-aminothiazole appears as light brown crystals or brown granular solid. (NTP, 1992)

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P351+P338, P319, P330, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 87 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: 2-Thiazolamine

Status: Active Update: 11-12-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21653

2-Aminothiazole: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include nausea, headache and weakness. It may also cause irritation.

Reactive GroupAmines, Phosphines, and Pyridines

Reactivity Profile2-AMINOTHIAZOLE reacts violently when nitrated with nitric or nitric-sulfuric acids. It is also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. (NTP, 1992)

Air and Water ReactionsInsoluble in water.

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)