슈퍼사이퍼메트린

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Refer for medical attention .

Use dry powder, carbon dioxide, alcohol-resistant foam, sand, or earth for dealing with fires. Do not use water. Cool nearby drums with water spray. If pyrethroid products are involved in a major fire or in a fire involving other products, advise the fire service that protective clothing and breathing apparatus should be worn. Also, warn the authorities that pyrethroids are highly toxic for fish, and that the use of water should be confined to the cooling of unaffected stock, thus avoiding the accumulation of polluted run-off from the site.

Extinguish fire using agent suitable for type of surrounding fire. /Pyrethrins/

Store technical material and formulations away from heat, under lock and key, and out of the reach of children, animals, and unauthorized personnel. Store in an area designated for insecticide storage, preferably without drains. Store away from other chemicals, foodstuffs, and animal feed.

Pyrethrins with piperonyl butoxide topical preparations should be stored in well-closed containers at a temperature less than 40 °C, preferably between 15-30 °C. /Pyrethrins/

Avoid exposure, if possible by the use of appropriate protective clothing and masks. Empty any product remaining in damaged or leaking containers into a clean empty drum and label. Absorb spillage with lime, damp sawdust, sand, or earth and dispose of safely (see below). If spillage is large, contain it by building a barrier of earth or sandbags. Decontaminate empty, damaged, or leaking containers with a 10% sodium carbonate solution added at the rate of at least 1 litre per 20 L drum. Puncture containers to prevent reuse.

/Transportation/ accident procedures: Avoid exposure - if possible by the use of appropriate protective clothing and masks. Keep spectators away from leaking or spilled product and prevent smoking or the use of naked flames in the immediate vicinity. Extinguish fires with dry powder, carbon dioxide, alcohol-resistant foam, sand, or earth. Prevent liquid from spreading to other cargo, vegetation, or waterways by containing it with the most readily available barrier material, e.g., earth or sand. Absorb spilled liquid and cover contaminated areas with earth, lime, sand, or other absorbent material. Sweep up and place in a secure container for subsequent safe disposal.

Spillages of pesticides at any stage of their storage or handling should be treated with great care. Liquid formulations may be reduced to solid phase by evaporation. Dry sweeping of solids is always hazardous: these should be removed by vacuum cleaning, or by dissolving them in water, or other solvent in the factory environment. /Pesticides/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Incinerate cypermethrin in a unit with effluent gas scrubbing. (Peer-review conclusions of an IRPTC expert (May 1985)).

Incineration would be an effective disposal procedure where permitted. If an efficient incinerator is not available, the product should be mixed with large amounts of combustible material and contact with the smoke should be avoided. /Pyrethrin products/

Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Do NOT wash away into sewer. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Avoid contact with skin. Keep out of any body of water. Do not contaminate water by cleaning of equipment or disposal of waste. Do not reuse empty container. Destroy it by perforating or crushing. /Pyrethrum/

If /pyrethrins/ are not involved in a fire: keep /pyrethrins/ out of water sources and sewers. Build dikes to contain flow as necessary. /Pyrethrins/

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

Following oral exposure, the treatment is symptomatic and supportive and includes monitoring for the development of hypersensitivity reactions with respiratory distress. Provide adequate airway management when needed. Gastric decontamination is usually not required unless the pyrethrin product is combined with a hydrocarbon. Following inhalation exposure, move patient to fresh air. monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If the contamination occurs through dermal exposure, Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. Vitamin E topical application is highly effective in relieving parenthesis. (L363)

The effects of dissolved organic carbon in the form of Aldrich humic acid on the accumulation and acute toxicities of three synthetic pyrethroids - fenvalerate, deltamethrin, and cyhalothrin - to Daphnia magna in laboratory experiments were investigated. Concn of dissolved organic carbon as low as 2.6 mg/L, 3.2 mg/L, and 3.1 mg/L for deltamethrin fenvalerate, and cyhalothrin, respectively, resulted in a significant decrease in bioaccumulation. Acute toxicities of all three pyrethroids were found to decrease as dissolved organic carbon concn increased; eg, at a dissolved organic carbon concn of 15.5 mg/L, the acute toxicity of fenvalerate was reduced by a factor of 17. The percentages of deltamethrin and fenvalerate bound to dissolved organic carbon increased as dissolved organic carbon concn increased after 2 hr and 24 hr contact times. At low concn of dissolved organic carbon (eg, 1.7 mg/L), as much as 40% of fenvalerate and 20% of deltamethrin were found sorbed to the dissolved material. After 24 hr contact times, 76.4 and 80.8% of fenvalerate and deltamethrin, respectively, were bound to dissolved organic carbon. Reverse-phase partition coefficients for both fenvalerate and deltamethrin were found to vary with dissolved organic carbon concn and were in the range 1.0 to 4.8 to 5.6.

The acute administration of 1R,cis, alpha S-cypermethrin, deltamethrin fenvalerate and permethrin produced a dose-dependent lowering of the dose of pentylenetetrazol required to elicit a seizure in rats. The proconvulsant action of cypermethrin displayed stereospecificity in that the 1R, cis, alpha S isomer of cypermethrin was the most potent compound tested, while the non-insecticidal isomer, 1S,cis, alpha R-cypermethrin, was devoid of proconvulsant activity. Pretreatment of rats with PK 11195, an antagonist of the peripheral-type benzodiazepine binding site, elicited a complete reversal of the proconvulsant actions of both deltamethrin and permethrin. In contrast, pretreatment with phenytoin did not alter the pyrethroid-induced proconvulsant activity. These results suggest that the effects of pyrethroids on pentylenetetrazol seizure threshold are mediated via an interaction with peripheral-type benzodiazepine binding sites.

/Pyrethroid/ detoxification ... important in flies, may be delayed by the addition of synergists ... organophosphates or carbamates ... to guarantee a lethal effect. ... /Pyrethroid/

Piperonyl butoxide potentiates /insecticidal activity/ of pyrethrins by inhibiting the hydrolytic enzymes responsible for pyrethrins' metabolism in arthropods. When piperonyl butoxide is combined with pyrethrins, the insecticidal activity of the latter drug is increased 2-12 times /Pyrethrins/

For more Interactions (Complete) data for CYPERMETHRIN (9 total), please visit the HSDB record page.

At high doses, signs of poisoning attributable to cypermethrin include profuse salivation and pulmonary edema, clonic seizures, opisthotonos (i.e., the spine is bent forward such that a supine body rests on its head and heels), coma, and death. At lower doses, commonly observed effects include paresthesia and erythema (L863).

LD50; Species: Anas platyrhynchos (Mallard duck, male) oral >9520 mg a.i./kg bw /92.9% a.i. technical/ /from table/

LD50; Species: Anas platyrhynchos (Mallard duck, female) oral >11227 mg a.i./kg bw /92.9% a.i. technical/ /from table/

LC50; Species: Anas platyrhynchos (Mallard duck, juvenile) diet >2634 ppm for 8 days

LD50; Species: Colinus virginianus (bobwhite quail) oral >2000 mg a.i./kg /97.1% a.i. Beta cypermethrin/ /from table/

For more Ecotoxicity Values (Complete) data for CYPERMETHRIN (67 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of 20,800 to 503,000(2-4), indicate that cypermethrin is expected be immobile in soil(SRC). Volatilization of cypermethrin from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.4X10-7 atm-cu m/mole(SRC), based upon its vapor pressure, 1.7X10-9 mm Hg(2), and water solubility, 4X10-3 mg/L(2). Cypermethrin is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(2). The photodegradation of the cis- and trans-isomers of cypermethrin were studied by exposing various soil surface applications to sunlight for 7-10 days(5); half-lives on soil surfaces exposed to sunlight ranged from 0.6-1.9 days while half-lives on dark soil were >7 days(5). The half-lives were 4.1 to 17.6 days for trans-cypermethrin and 12.5 to 56.4 days for the cis-cypermethrin under aerobic conditions in an incubated soil(5), indicating rapid biodegradation. After spray applications in an orchard, the half-life of cypermethrin on vegetation under pear and apricot trees ranged from 14-17 days(6); soil contained no detectable cypermethrin after 100-120 days(6). After spraying wheat herbage, cypermethrin residues fell to 50% after 1 day and to 5% after 27 days(7).

TERRESTRIAL FATE: Cypermethrin degradation in soil was rapid, the trans-isomer degraded more rapidly than the cis-isomer. Thirty to 60% of cypermethrin applied was converted to (14)CO2. Hydrolysis of the ester was the primary pathway and produced the carboxylic acid plus 3-phenoxybenzyl alcohol or 3-phenoxybenzaldehyde cyanohydrin. Both of the latter compounds were converted to 3-phenoxybenzoic acid. Another pathway produced the 3-(4-hydroxyphenoxy)benzyl ester which was in turn hydrolyzed. The degradation rate of trans-cypermethrin and cis-cypermethrin was most rapid on sandy clay and sandy loam. About 50% of trans-cypermethrin and cis-cypermethrin applied to the soils decomposed in 2 weeks and 4 weeks, respectively. Six degradation products were observed in soil: the 3-(4-hydroxyphenoxy)benzyl ester; 3-(4-hydroxyphenoxy)benzoic acid; 3-phenoxybenzoic acid; and (+ or -)-cis- and (+ or -)-trans-3-(2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylic acid. Carbon dioxide was also observed.

AQUATIC FATE: Based on a classification scheme(1), Koc values of 20,800 to 503,000(2-4), indicate that cypermethrin is expected to adsorb to suspended solids and sediment(SRC). In a pond experiment, surface applications of cypermethrin gradually partitioned to sediment with sediment concentrations exceeding surface and subsurface water concentrations after 13 days(5); in another pond experiment, dispersion of surface applications to subsurface water and sediment was very slow(5); however, after 4 wks, the concentration in the sediment exceeded the water concentrations(5). Volatilization from water surfaces is not expected(6) based upon an estimated Henry's Law constant of 2.4X10-7 atm-cu m/mole(SRC), derived from its vapor pressure, 1.7X10-9 mm Hg(2), and water solubility, 0.004 mg/L(2). According to a classification scheme(7), BCFs of 420 in golden ide fish (Leuciscus idus melanotus)(8), 430 in rainbow trout (Oncorhynchus mykiss)(9) and 468 in bluegill (Lepomis macrochirus)(10) suggest bioconcentration in aquatic organisms is high(SRC). Cypermethrin was found to be stable to hydrolysis at pH 5 and 7, and had a half-life of 1.8 to 2.5 days at pH 9(3). The photodegradation of the cis- and trans-isomers of cypermethrin was studied by exposing various aqueous solutions to sunlight for 7-10 days; the half-lives in distilled water solution were 2.6-3.6 days in sunlight and >10 days in dark controls(11); the half-lives in river and seawater were 0.6-1.0 days and >10 days in dark controls(11). Cypermethrin is expected to biodegrade based on biodegradation half-lives of 11.6 to 30.4 days in water at 15 to 19 °C, pH 7.7, and biological oxygen demand of 2.2 mg/L(12). Anaerobic and aerobic half-lives of cypermethrin in water of 9 to 17 days were also reported(2).

According to compiled results of the US Food and Drug Administration's pesticide residue monitoring programs (including the Total Diet Study) for fiscal years 1978-1990, cypermethrin has been detected as a pesticide residue in American foods(1-4). As part of the FDA Total Diet Study, the concentrations of cypermethrin detected in boiled collards, raw iceberg lettuce, and boiled broccoli were 0.442 ppm (range, 0.052-1.247 ppm), 0.0185 ppm (range, 0.013-0.024 ppm), and 0.013 ppm, respectively(5). During a 5-yr period from 1982-1986, FDA's Los Angeles District Laboratory analyzed 19,581 samples of domestic and imported food and feed commodities for pesticide residues(2); cypermethrin was detected in only 2 samples at concentrations of 0.1-0.5 ppm(2). For fiscal years 1988 and 1989, 27,065 food samples were collected and analyzed for pesticide residues by 10 state laboratories (CA, NY, FL, IN, MA, MI, NC, OR, VA and WI)(6); cypermethrin was detected in only 1 sample (concentration not reported)(7). Fruits (802) and vegetables (1536) collected by the food inspection branch from farms, food terminals, warehouses and points of consumer purchase in Ontario, Canada 1991 to 1995 had 221 reported detections of cypermethrin at <5 ug/g(8).

Between July 1988 and June 1990 in Pakistan, foods were tested for cypermethrin residues(1). Cypermethrin was not detected in fenugreek, aubergine(brinjal), sweet potato, potato, green pepper, capsicum, radish, garlic, peas, french beans, mustard, ginger, arum, gourd, cow pea, radish seeds, parsley, long cucumber, cluster bean, lemon, peach, apple, persimmon (amlok), banana, pomegranate, grapes, musk melon, orange, grapefruit, papaya, sapota, Ziziphus, cherry, plum, apricot, pear, watermelon, sugar cane, or cheeko in the same study(1).

Cypermethrin was analyzed in 397 samples collected in 8 local markets from 6 Egyptian governorates (Cairo, Giza, Qualubiya, Beni Suef, Minufiya and Ismailia) in 1995 and was reported not detected in cabbage, cauliflower, carrot, courgette, cucumber, eggplant, green beans, green peas, lettuce, onion, pepper, apple, cantaloupe, grape, guava, mango, orange, peach or strawberry, but was detected in 1 of 62 tomato samples at a concentration of 1.1 mg/kg(1). Cypermethrin was also analyzed in 1579 samples collected in the same Egyptian governorates in 1996 and was not detected in cabbage, grape leaf, lettuce, melokhia, spinach, watercress, artichoke, broad bean, cauliflower, cantaloupe, cucumber, eggplant, green beans, green peas, okra, onion, pepper, squash, carrot, sweet potato, taro, banana, fig, lemon, lime, mango, peach, pear, plum, or pomegranate(2). Cypermethrin was detected in 8 of 86 tomato at 0.28 mg/kg, 1 of 49 apple at 0.14 mg/kg, 1 of 5 apricot at 0.57 mg/kg, 4 of 54 date at 0.37 mg/kg, 3 of 47 grape at 0.46 mg/kg, 1 of 72 guava at 0.12 mg/kg, 1 of 64 orange at 0.05 mg/kg and 2 of 38 strawberry at 0.35 mg/kg(2). Cypermethrin was detected in 20% of 30 tomato samples and 30% of 20 grape samples at 2.4 to 19.1 and 4.1 to 30.1 ppb, respectively, in samples taken from Alexandria City, Egypt from June 1997 to August 1998(4). Cypermethrin was undetected (detection limit 1.0 ppb) in 10 eggplant, 20 cucumber, 18 potato, 12 apple and 12 orange samples taken in the same survey(3).

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Inhalation (L857) ; oral (L857) ; dermal (L857) ; eye contact (L857).

ENVIRONMENTAL: Pyrethroids (permethrin, cyfluthrin, cypermethrin and deltamethrin) were found in the breastmilk of nursing mothers in 3 South African towns. Average levels in breastmilk ranged from 8.3 to 48.4 mcg/L in the 3 towns. The source was thought to be from a dusting powder widely available and used in gardening. The dosage and route of exposure (i.e., topical, inhalation, oral) could not be determined. All milk levels were below the allowable daily limit for permethrin.

A study was undertaken to determine residues of cypermethrin in the milk of cows wearing ear tags impregnated with cypermethrin (to control horn flies and other insects)(1); 60 milk samples were collected from 10 cows over a 21-day period(1); 49 samples were below detection limits of 4 ug/kg(1); concentrations in the butterfat of the other samples ranged from 4.0 to 9.6 ug/kg(1).

Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in the immediate vicinity of the sodium channel, thus modifying the channel kinetics. This blocks the closing of the sodium gates in the nerves, and thus prolongs the return of the membrane potential to its resting state. The repetitive (sensory, motor) neuronal discharge and a prolonged negative afterpotential produces effects quite similar to those produced by DDT, leading to hyperactivity of the nervous system which can result in paralysis and/or death. Other mechanisms of action of pyrethroids include antagonism of gamma-aminobutyric acid (GABA)-mediated inhibition, modulation of nicotinic cholinergic transmission, enhancement of noradrenaline release, and actions on calcium ions. They also inhibit calium channels and Ca2+, Mg2+-ATPase. (T10, T18, L857)

/BIRDS and MAMMALS/ Results of reproductive studies in mallard ducks and bobwhite quail show no treatment-related effects on adult birds, reproductive parameters, or offspring at the highest dietary concentrations tested in these studies (50 mg a.i/kg diet).

/AQUATIC SPECIES/ ... A freshwater fish Channa punctatus was exposed to subacute concentrations of ... cypermethrin ... for 96 hr ... Significant enhancement in the level of DNA was recorded in all tissues of the fish at high concentration of cypermethrin, whereas RNA and protein contents increased in tissues at all concentrations of cypermethrin tested. ... Cypermethrin treatment induced RNA/DNA ratio in all fish organs tested ... . Protein/DNA ratios were found to be tissue specific in treatments ...

/AQUATIC SPECIES/ ... This paper investigate/s/ the response of GST activity in the /shore crab, Carcinus maenas exposed to cypermethrin/, and also the time course of the induction process. GST activity is significantly increased in Carcinus exposed to nominal concentrations of 50 and 500 ng/L of water-borne cypermethrin. Carcinus demonstrate a significant elevation in GST activity following intra-cephalothoracic injection with 10 ng of cypermethrin. GST activity returns to basal levels after 36 hr. The potential application of GST activity in Carcinus as a biomarker of cypermethrin exposure is discussed. 206409

/AQUATIC SPECIES/ The effect of exposure to sub-lethal concentrations of cypermethrin ... on biochemical parameters of muscle, blood and enzyme activities in brain, liver and kidney of the Indian major carp, Labeo rohita was studied. The sub-lethal exposure studies were done for up to 45 days at 1/10 and 1/50 of 96 hr LC50 of cypermethrin. The 96 hr LC50 was found to be 0.139 ppm. RNA levels decreased while DNA levels were elevated. Acid phosphatase was unchanged while alkaline phosphatase was depleted. Brain acetylcholinesterase activity was decreased significantly (P<0.05) over a period of 45 days at both cypermethrin concentrations. Lactate dehydrogenase activity in brain and liver was elevated, but inhibited in kidney. Succinate dehydrogenase and ATPase activities were depleted in brain, kidney and liver. There was a decrease in serum protein level over control at both concentrations of the pyrethroid. Blood glucose level and total leucocytes were elevated compared with controls at either concentration from day 15 to day 45. Hemoglobin percentage and total erythrocytes decreased in both sub-lethal concentrations. ...

For more Ecotoxicity Excerpts (Complete) data for CYPERMETHRIN (44 total), please visit the HSDB record page.

Tolerances are established for residues of the insecticide cypermethrin (+/-)alpha cyano-(3-phenoxyphenyl)methyl(+/-)cis,trans-3(2,2-dichloroethenyl-2,2-dimethylcyclopropanecarboxylate in or on the following commodities: [Table#6094]

Tolerances are established for residues of the insecticide Z-cypermethrin (S-cyano(3-phenoxyphenyl) methyl (+/-))(cis-trans 3-(2,2-dichloroethenyl)-2,2 dimethylcyclopropanecarboxylate and its inactive R-isomers in or on the following raw agricultural commodities: /zeta-Cypermethrin/ [Table#6095]

The Agency has completed its assessment of the dietary, residential, occupational and ecological risk associated with the use of cypermethrin. Based on this assessment the Agency has sufficient information to make decisions as part of the tolerance reassessment process under FFDCA and reregistration process under FIFRA, as amended by FQPA. The Agency has determined that cypermethrin containing products are eligible for reregistration provided that label amendments are made as outlined in this RED. ... Based on its evaluation of cypermethrin, the Agency has determined that cypermethrin products, unless labeled and used as specified in this document, would present risks inconsistent with FIFRA and FQPA. Accordingly, should a registrant fail to implement any of the reregistration requirements identified in this document, the Agency may take regulatory action to address the risk concerns from the use of cypermethrin. If all changes outlined in this document are incorporated into the product labels, then all current risks for cypermethrin will be adequately mitigated for the purposes of this determination.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their continued use. Under this pesticide reregistration program, EPA examines newer health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether the use of the pesticide does not pose unreasonable risk in accordance to newer saftey standards, such as those described in the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA '88 were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern than those on List C, and with List C containing pesticides of greater concern than those on List D. Cypermethrin is found on List B. Case No: 2130; Pesticide type: Insecticide (Acaricide); Case Status: OPP is reviewing data from the pesticide's producers regarding its human health and/or environmental effects, or OPP is determining the pesticide's eligibility for reregistration and developing the Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): alpha-cyano(3-phenoxyphenyl)methyl(+-)cis,trans-3-(2,2-dichlorovinyl- 2,2-dimethylcyclopropanecarboxylate; Data Call-in (DCI) Date(s): 07/01/91, 03/03/95, 10/13/95; AI Status: The producers of the pesticide have made commitments to conduct the studies and pay the fees required for reregistration, and are meeting those commitments in a timely manner.

Pyrethrins are insecticides used mainly in households; Also used to kill insects on pets and in grain storage bins and poultry pens. Dusts containing 0.3% to 0.5% pyrethrins are used on crops. [EXTOXNET]

Farming (Pesticides) [Category: Industry]

For cypermethrin (USEPA/OPP Pesticide Code: 109702) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Insecticides (pyrethroid ester insecticides) (Compend Pest Common Names available at

For zeta-cypermethrin (USEPA/OPP Pesticide Code: 129064) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ /zeta-Cypermethrin/

Cypermethrin is registered for agricultural use as a foliar application on food and feed crops including cotton, pecans, peanuts, broccoli and other Brassicas, and sweet corn. Cypermethrin can be applied to livestock in eartags, and to horses. Cypermethrin is also registered for use on industrial, commercial, and residential sites. It is registered for outdoor use as a soil residual termiticide and to control insect pests such as ants in and on structures, impervious surfaces (in perimeter and crack and crevice treatments) and lawns. Cypermethrin can also be applied indoors to control ants, cockroaches, fleas, and other insects.

Emulsifiable concentrate, ULV, wettable powder.

PREMIX PARTNERS: Acetamiprid; Amitraz; Chlorpyrifos; Chlorpyrifos-methyl; Dichlorvos; Dimethoate; Endosulfan; Ethion; Fenitrothion; Malathion; Phenthoate; Piperonyl Butoxide; Profenofos; Quinalphos; Tetramethrin.

Emulsifiable concentrate. /zeta-Cypermethrin/

PREMIX PARTNERS: Bifenthrin. /zeta-Cypermethrin/

For more Formulations/Preparations (Complete) data for CYPERMETHRIN (111 total), please visit the HSDB record page.

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

Insecticides

Environmental transformation -> Pesticides (parent, predecessor)

The WHO Recommended Classification of Pesticides by Hazard identifies cypermethrin (technical grade) as Class IB: highly hazardous; Main Use: insecticide.

Natural pyrethrins, the insecticidal ingredient occurring in the flowers of Tanacetum cinerariaefolium (also known as Chrysanthemum cinerariaefolium or Pyrethrum cineratiae-folium), have been used widely for human and animal health protection by controlling indoor pest insects such as cockroaches, houseflies, and mosquitoes. Natural pyrethrins consist of six compounds (pyrethrin I and II; jasmolin I and II; and cinerin I and II). ... Extensive efforts on modification of chemical structures have been made ... to improve chemical properties in terms of stability in the environment (air, light, and heat) as well as better biological performance (higher selective toxicology). From these investigations, many synthetic pyrethroids have been elaborated ... . They can be classified into the so-called first-generation pyrethroids, which are esters of chrysanthemic acid and alcohols having furan ring and terminal side chain moieties, is to be he highly sensitive to light, air, and temperature. Therefore, these pyrethroids have been used mainly for control of indoor pests. On the other hand, the second generation pyrethroids, which commonly have 3-phenoxybenzyl alcohol derivatives in the alcohol moiety, have excellent insecticidal activity as well as sufficient stability in outdoor conditions by replacement of photolabile moieties with dichlorovinyl, dibromovinyl substituent and aromatic rings. Thus, the second generation pyrethroids are used worldwide for agricultural pests.

The WHO Recommended Classification of Pesticides by Hazard identifies alpha-cypermethrin (technical grade) as Class II: moderately hazardous; Main Use: insecticide. /alpha-Cypermethrin/

alpha-Cypermethrin ... Insecticide ... US: Currently not registered. Outside US: in Jordan. /alpha-Cypermethrin/

For more General Manufacturing Information (Complete) data for CYPERMETHRIN (12 total), please visit the HSDB record page.