Amonafide

H <1 (mg/mL)

pH 4 acetate buffer ~10 (mg/mL)

pH 9 carbonate buffer < 1 (mg/mL)

0.1 N HC1 ~20 (mg/mL)

0.1 N NaOH < 1 (mg/mL)

10% Ethanol < 1 (mg/mL)

Substances that inhibit or prevent the proliferation of NEOPLASMS.

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.